ACUTE EFFECT OF CIGARETTE SMOKING ON VENTRICULAR REPOLARIZATION PARAMATERS

Abstract

Background: Acute cigarette smoking has been reported to increase heart rate and blood pressure as a consequence of sympathetic stimulation. In this study we sought to determine if single dose cigarette smoking influences ventricular repolarization paramaters in habitual smokers. Method and Results: The study population consisted of twenty-four long-term heavy smokers. A 12-lead surface ECG recorded at a paper speed of 50 ms/s was obtained from all participants before and average 15 min. after cigarette smoking. Maximum QT (QTmax), minimum QT (QTmin) intervals, QT dispersion (QTd) and corrected QT dispersion (QTcd) were calculated on each ECG record. QT and RR intervals in V2 leads (QTV2 and RRV2) were also measured before and after smoking. Hart rate and RRV2 significantly increased after smoking a cigarette (67±7 vs. 72±8 beat/min, 984±169ms vs. 875±150ms, respectively p

Keywords

• Cigarette smoking, ventricular repolarization, andarrhythmia.

ACUTE EFFECT OF CIGARETTE SMOKING ON VENTRICULAR REPOLARIZATION PARAMATERS

Abstract

Background: Acute cigarette smoking has been reported to increase
heart rate and blood pressure as a consequence of sympathetic
stimulation. In this study we sought to determine if single dose
cigarette smoking influences ventricular repolarization paramaters
in habitual smokers.
Method and Results:The study population consisted of twenty-four
long-term heavy smokers. A 12-lead surface ECG recorded at a
paper speed of 50 ms/s was obtained from all participants before and
average 15 min. after cigarette smoking. Maximum QT (QTmax),
minimum QT (QTmin) intervals, QT dispersion (QTd) and
corrected QT dispersion (QTcd) were calculated on each ECG
record. QT and RR intervals in V2 leads (QTV2 and RRV2) were
also measured before and after smoking. Hart rate and RRV2
significantly increased after smoking a cigarette (67±7 vs. 72±8
beat/min, 984±169ms vs. 875±150ms, respectively p<0.05).
However, the other parameters including QTmax, QTmin, QTd,
QTcd and QTV2 did not alter compared to baseline values.
Concusion:Single dose cigarette smoking does not seem to be
associated with ventricular heterogeneity both in habitual smokers
although it leads to sympathetic hyperactivity.

Keywords

• Cigarette smoking,ventricular repolarization,and arrhythmia

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