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Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması ve İnflamasyon İlişkisi

Year 2014, Volume: 17 Issue: 1, 11 - 14, 01.01.2013
https://doi.org/10.4274/khj.6648

Abstract

AMAÇ: Coronary artery aneurysm is generally presented as an asymptomatic, incidental angiographic finding and is often associated with atherosclerosis. In this study we investigated the relation of non-atherosclerotic isolated coronary artery aneurysm with inflammation.YÖNTEMLER: SİAGHP enfeksiyonu olan 60 kişi, sitotoksin ilişkili A geni negatif H. pylori (SAİGNHP) enfeksiyonlu 40 kişi ve enfeksiyonu olmayan 50 kişi ile akım aracılı dilatasyon (AAD), endotele bağımlı olmayan dilatasyon (EBOD) ve CRP düzeyleri yönünden karşılaştırıldı.BULGULAR: SİAGHP'li bireylerde ortalama AAD'nin yüzdesi (6.3±2.7) SİAGNHP olanlardan (9.8±3.3, p

References

  • Boles U, Eriksson P, Zhao Y, Henein MY. Coronary artery ectasia: remains a clinical dilemma. Coron Artery Dis 2010;21:318-20.
  • Akcakoyun M, Pala S, Esen O, Acar G, Kargin R, Emiroglu Y, et al. Dilatation of the ascending aorta is associated with low serum prolidase activity. Tohoku J Exp Med 2010;220:273-7.
  • Bakuy V, Gursoy M, Hokenek F, Gedikbasi A, Atay M, Nurdag A, et al. Prolidase Activity in Patients With Coronary Artery Aneurysm. Angiology 2013. (Epub ahead of print)
  • Işık T, Ayhan E, Uyarel H, Tanboğa IH, Kurt M, Uluganyan M, et al. Association of neutrophil to lymphocyte ratio with presence of isolated coronary artery ectasia. Turk Kardiyol Dern Ars 2013;41:123-30.
  • Erdoğan T, Kocaman SA, Çetin M, Durakoğlugil ME, Kırbaş A, Canga A, et al. Increased YKL-40 levels in patients with isolated coronary artery ectasia: an observational study. Anadolu Kardiyol Derg 2013; 13:465-70.
  • 6- Triantafyllis AS, Kalogeropoulos AS, Rigopoulos AG, Sakadakis EA, Toumpoulis IK, Tsikrikas S, et al. Coronary artery ectasia and inflammatory cytokines: Link with a predominant Th-2 immune response? Cytokine 2013;64:427-32.
  • Kurt M, Karakaş MF, Büyükkaya E, Büyükkaya Ş, Karakaş E, Motor S, et al. The relation of serum Pentraxin-3 levels with coronary artery ectasia. Kosuyolu Kalp Derg 2013;16:87-92.
  • Ruggiero C, Cherubini A, Ble A, Bos AJ, Maggio M, Dixit VD, et al. Uric acid and inflammatory markers. Eur Heart J 2006;27:1174-81.
  • Pahlavan PS, Niroomand F. Coronary artery aneurysm: a review. Clin Cardiol 2006;29:439-43.
  • Antoniadis AP, Chatzizisis YS, Giannoglou GD. Pathogenetic mechanisms of coronary ectasia. Int J Cardiol 2008;130:335-43.
  • Akyel A, Sahinarslan A, Kiziltunc E, Yıldız U, Alsancak Y, Akboga MK, et al. Neutrophil gelatinase-associated lipocalin levels in isolated coronary artery ectasia. Can J Cardiol 2011;27:773-8.
  • Ramos-Mozo P, Madrigal-Matute J, Martinez-Pinna R, Blanco-Colio LM, Lopez JA, Camafeita E, et al. Proteomic analysis of polymorphonuclear neutrophils identifies catalase as a novel biomarker of abdominal aortic aneurysm: potential implication of oxidative stress in abdominal aortic aneurysm progression. Arterioscler Thromb Vasc Biol 2011;31:3011-9.
  • Koc F, Kalay N, Ardic I, Ozbek K, Celik A, Ceyhan K, et al. Antioxidant status and levels of antioxidant vitamins in coronary artery ectasia. Coron Artery Dis 2011;22:306-10.
  • Sezen Y, Bas M, Polat M, Yildiz A, Buyukhatipoglu H, Kucukdurmaz Z, et al. The relationship between oxidative stress and coronary artery ectasia. Cardiol J 2010;17:488-94.
  • Esen AM, Akcakoyun M, Esen O, Acar G, Emiroglu Y, Pala S, et al. Uric acid as a marker of oxidative stress in dilatation of the ascending aorta. Am J Hypertens 2011;24:149-54.
  • Piechota-Polanczyk A, Goraca A, Demyanets S, Mittlboeck M, Domenig C, Neumayer C, et al. Simvastatin decreases free radicals formation in the human abdominal aortic aneurysm wall via NF-κB. Eur J Vasc Endovasc Surg 2012;44:133-7.
  • Hasan DM, Chalouhi N, Jabbour P, Dumont AS, Kung DK, Magnotta VA, et al. Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results. J Am Heart Assoc 2013;2:e000019.
  • Dopp JM, Philippi NR, Marcus NJ, Olson EB, Bird CE, Moran JJ, et al. Xanthine oxidase inhibition attenuates endothelial dysfunction caused by chronic intermittent hypoxia in rats. Respiration 2011;82:458-67.
  • George J, Struthers AD. Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress. Vasc Health Risk Manag 2009;5:265- 72.
  • Tausche AK, Christoph M, Forkmann M, Richter U, Kopprasch S, Bielitz C, et al. As compared to allopurinol, urate lowering therapy with febuxostat has superior effects on oxidative stres and pulse velocity in patients with severe chronic tophaceous gout. Rheumatol Int 2014;34:101-9.

Inflammation and Non-atherosclerotic Coronary Artery Aneurysm

Year 2014, Volume: 17 Issue: 1, 11 - 14, 01.01.2013
https://doi.org/10.4274/khj.6648

Abstract

OBJECTIVE: Cytotoxin associated gene (Cag) A+ Helicobacter pylori (HP) is the most virulent HP strain, and its association with endothelial dysfunction remains unclear. Thus we investigated the effects of CagA+ HP on endothelial dependent dilatation and its relationship with C-reactive protein (CRP) in normotensive subjects. METHODS: Sixty individuals with CagA+ HP infection were compared with 40 individuals with CagA(-) HP infection and 50 individuals with no infection in terms of flow-mediated dilatation (FMD), non-endothelium-dependent dilatation (NED) and CRP.RESULTS: In the CagA+ subjects the mean percentage of FMD was 6.3±2.7, which was significantly lower than that of the CagA- subjects (9.8±3.3, p

References

  • Boles U, Eriksson P, Zhao Y, Henein MY. Coronary artery ectasia: remains a clinical dilemma. Coron Artery Dis 2010;21:318-20.
  • Akcakoyun M, Pala S, Esen O, Acar G, Kargin R, Emiroglu Y, et al. Dilatation of the ascending aorta is associated with low serum prolidase activity. Tohoku J Exp Med 2010;220:273-7.
  • Bakuy V, Gursoy M, Hokenek F, Gedikbasi A, Atay M, Nurdag A, et al. Prolidase Activity in Patients With Coronary Artery Aneurysm. Angiology 2013. (Epub ahead of print)
  • Işık T, Ayhan E, Uyarel H, Tanboğa IH, Kurt M, Uluganyan M, et al. Association of neutrophil to lymphocyte ratio with presence of isolated coronary artery ectasia. Turk Kardiyol Dern Ars 2013;41:123-30.
  • Erdoğan T, Kocaman SA, Çetin M, Durakoğlugil ME, Kırbaş A, Canga A, et al. Increased YKL-40 levels in patients with isolated coronary artery ectasia: an observational study. Anadolu Kardiyol Derg 2013; 13:465-70.
  • 6- Triantafyllis AS, Kalogeropoulos AS, Rigopoulos AG, Sakadakis EA, Toumpoulis IK, Tsikrikas S, et al. Coronary artery ectasia and inflammatory cytokines: Link with a predominant Th-2 immune response? Cytokine 2013;64:427-32.
  • Kurt M, Karakaş MF, Büyükkaya E, Büyükkaya Ş, Karakaş E, Motor S, et al. The relation of serum Pentraxin-3 levels with coronary artery ectasia. Kosuyolu Kalp Derg 2013;16:87-92.
  • Ruggiero C, Cherubini A, Ble A, Bos AJ, Maggio M, Dixit VD, et al. Uric acid and inflammatory markers. Eur Heart J 2006;27:1174-81.
  • Pahlavan PS, Niroomand F. Coronary artery aneurysm: a review. Clin Cardiol 2006;29:439-43.
  • Antoniadis AP, Chatzizisis YS, Giannoglou GD. Pathogenetic mechanisms of coronary ectasia. Int J Cardiol 2008;130:335-43.
  • Akyel A, Sahinarslan A, Kiziltunc E, Yıldız U, Alsancak Y, Akboga MK, et al. Neutrophil gelatinase-associated lipocalin levels in isolated coronary artery ectasia. Can J Cardiol 2011;27:773-8.
  • Ramos-Mozo P, Madrigal-Matute J, Martinez-Pinna R, Blanco-Colio LM, Lopez JA, Camafeita E, et al. Proteomic analysis of polymorphonuclear neutrophils identifies catalase as a novel biomarker of abdominal aortic aneurysm: potential implication of oxidative stress in abdominal aortic aneurysm progression. Arterioscler Thromb Vasc Biol 2011;31:3011-9.
  • Koc F, Kalay N, Ardic I, Ozbek K, Celik A, Ceyhan K, et al. Antioxidant status and levels of antioxidant vitamins in coronary artery ectasia. Coron Artery Dis 2011;22:306-10.
  • Sezen Y, Bas M, Polat M, Yildiz A, Buyukhatipoglu H, Kucukdurmaz Z, et al. The relationship between oxidative stress and coronary artery ectasia. Cardiol J 2010;17:488-94.
  • Esen AM, Akcakoyun M, Esen O, Acar G, Emiroglu Y, Pala S, et al. Uric acid as a marker of oxidative stress in dilatation of the ascending aorta. Am J Hypertens 2011;24:149-54.
  • Piechota-Polanczyk A, Goraca A, Demyanets S, Mittlboeck M, Domenig C, Neumayer C, et al. Simvastatin decreases free radicals formation in the human abdominal aortic aneurysm wall via NF-κB. Eur J Vasc Endovasc Surg 2012;44:133-7.
  • Hasan DM, Chalouhi N, Jabbour P, Dumont AS, Kung DK, Magnotta VA, et al. Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results. J Am Heart Assoc 2013;2:e000019.
  • Dopp JM, Philippi NR, Marcus NJ, Olson EB, Bird CE, Moran JJ, et al. Xanthine oxidase inhibition attenuates endothelial dysfunction caused by chronic intermittent hypoxia in rats. Respiration 2011;82:458-67.
  • George J, Struthers AD. Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress. Vasc Health Risk Manag 2009;5:265- 72.
  • Tausche AK, Christoph M, Forkmann M, Richter U, Kopprasch S, Bielitz C, et al. As compared to allopurinol, urate lowering therapy with febuxostat has superior effects on oxidative stres and pulse velocity in patients with severe chronic tophaceous gout. Rheumatol Int 2014;34:101-9.
There are 20 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Mete Gürsoy This is me

Abdulkadir Faruk Hökenek This is me

Vedat Bakuy This is me

Egemen Duygu This is me

Murat Şener This is me

Publication Date January 1, 2013
Published in Issue Year 2014 Volume: 17 Issue: 1

Cite

APA Gürsoy, M. ., Hökenek, A. F. ., Bakuy, V. ., Duygu, E. ., et al. (2013). Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması ve İnflamasyon İlişkisi. Koşuyolu Kalp Dergisi, 17(1), 11-14. https://doi.org/10.4274/khj.6648
AMA Gürsoy M, Hökenek AF, Bakuy V, Duygu E, Şener M. Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması ve İnflamasyon İlişkisi. Koşuyolu Kalp Dergisi. January 2013;17(1):11-14. doi:10.4274/khj.6648
Chicago Gürsoy, Mete, Abdulkadir Faruk Hökenek, Vedat Bakuy, Egemen Duygu, and Murat Şener. “Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması Ve İnflamasyon İlişkisi”. Koşuyolu Kalp Dergisi 17, no. 1 (January 2013): 11-14. https://doi.org/10.4274/khj.6648.
EndNote Gürsoy M, Hökenek AF, Bakuy V, Duygu E, Şener M (January 1, 2013) Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması ve İnflamasyon İlişkisi. Koşuyolu Kalp Dergisi 17 1 11–14.
IEEE M. . Gürsoy, A. F. . Hökenek, V. . Bakuy, E. . Duygu, and M. . Şener, “Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması ve İnflamasyon İlişkisi”, Koşuyolu Kalp Dergisi, vol. 17, no. 1, pp. 11–14, 2013, doi: 10.4274/khj.6648.
ISNAD Gürsoy, Mete et al. “Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması Ve İnflamasyon İlişkisi”. Koşuyolu Kalp Dergisi 17/1 (January 2013), 11-14. https://doi.org/10.4274/khj.6648.
JAMA Gürsoy M, Hökenek AF, Bakuy V, Duygu E, Şener M. Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması ve İnflamasyon İlişkisi. Koşuyolu Kalp Dergisi. 2013;17:11–14.
MLA Gürsoy, Mete et al. “Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması Ve İnflamasyon İlişkisi”. Koşuyolu Kalp Dergisi, vol. 17, no. 1, 2013, pp. 11-14, doi:10.4274/khj.6648.
Vancouver Gürsoy M, Hökenek AF, Bakuy V, Duygu E, Şener M. Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması ve İnflamasyon İlişkisi. Koşuyolu Kalp Dergisi. 2013;17(1):11-4.