Koroner Arter Baypas Cerrahisi Sonrası Hastalarda Mortalite Belirteci Olarak Preoperatif Kırmızı Küre Dağılım Hacmi

Year 2013, Volume: 16 Issue: 1, 1 - 6, 01.01.2012

İrfan Taşoğlu Osman Turak Fırat Özcan Yunus Nazlı Ersin Kadiroğulları Murat Songur Doğan Sert Metin Yılmaz Aslı Demir Alper Uzun

https://doi.org/10.5578/kkd.4603

Abstract

Giriş: Biz kırmızı küre dağılım hacmi (RDW)'nin koroner arter hastalarında cerrahi revaskülarizasyon sonrası sonuçlarda belirleyici olduğunu düşündük. Gereç ve Yöntem: Ciddi koroner arter hastalığı olan koroner baypas cerrahisi geçirmiş 94 hasta çalışmaya dahil edildi. Toplam 94 hasta RDW değerlerine göre üç gruba ayrıldı (mean RDW: tertile 1, 12.68 ± 0.60; tertile 2: 13.64 ± 0.49; tertile 3, 16.47 ± 2.04). Bulgular: Ortalama 51 aylık takipte toplam 18 (%19.1) ölüm gözlendi. Yüksek RDW'li hastalar orta (%10) ve düşük (%13) RDW'li hastalara kıyasla yüksek mortalite gösterdi. Değişkenli regresyon analizinde RDW > 14.6 beş yıllık sonuçlar için önemli bağımsız risk faktörüdür. Sonuç: Sonuç olarak, koroner baypas cerrahisi geçirmiş hastaların preoperatif yüksek RDW değeri artmış uzun dönem mortalite riski ile ilişkilidir.

Keywords

Koroner arter baypas; mortalite; morbidite; kırmızı küre dağılım hacmi.

Preoperative Red Cell Distribution Width as a Predictor of Mortality in Patients After Coronary Artery Bypass Grafting

Abstract

Introduction: We hypothesized that the red cell distribution width (RDW) would predict the outcome of surgical revascularization of patients with coronary artery disease. Materials and Methods: Ninety four patients with severe coronary artery disease who underwent coronary artery bypass grafting were included in this study. A total of 94 patients were divided into tertiles based on their preprocedural RDW (mean RDW: tertile 1, 12.68 ± 0.60; tertile 2: 13.64 ± 0.49; tertile 3, 16.47 ± 2.04). Results: There were a total of 18 (19.1%) deaths over a mean follow-up of 51 months. Patients with a high RDW showed the highest mortality (34%) as compared to patients with medium (10%) and low RDW (13%). In multivariable regression modeling, RDW > 14.6 was a significant independent predictor of five year outcome in mortality. Conclusion: In conclusion, elevated preprocedural RDW in patients undergoing coronary artery bypass grafting is associated with increased risk of long-term mortality.

Keywords

Coronary artery bypass grafting; mortality; morbidity; red cell distribution width.

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