Heart Rate Variability in Patients with Chronic Obstructive Pulmonary Disease Treated by Noninvasive Mechanic Ventilation

Year 2011, Volume: 14 Issue: 2, 39 - 44, 01.02.2010

Yusuf Karavelioğlu Hekim Karapınar Zuhal Karakurt Alim Erdem Zekeriya Kaya İbrahim Gül Zekeriya Küçükdurmaz Özlem Yazıcıoğlu Moçin Cevat Kırma

Abstract

Aims: This study aimed to investigate heart rate variability (HRV) of patients with severe COPD who are treated by noninvasive mechanic ventilation (NIMV). Patients and Method: Twenty-seven patient (58±8 years, 9 F) with severe COPD treated by nocturnal NIMV at home and 23 sex and age matched volunteYusuf ers (56±8 years, 11 F) who has not dyspnea as a control group recruited in the study. Subjects underwent spirometry, blood gas analysis, transthoracic echocardiography, 24 hours ambulatory ECG analysis. Time domain HRV analysis performed from ambulatory ECG records. Results: 52% of patients at NYHA functional class II, 36% at class III, and 12% at class IV when they have been treated by NIMV. Groups were similar for age and sex (p>0.05 for both). Heart rates of patients were higher significantly than controls' (p0.05). But, systolic pulmonary pressures were higher of COPD group (p

Keywords

Chronic Obstructive Pulmonary Disease, Noninvasive Mechanic Ventilation, Heart Rate Variability.

Noninvaziv Mekanik Ventilatör Kullanan Kronik Obstrüktif Akciğer Hastalıklı Hastalarda Kalp Hızı Değişkenliği

Abstract

Amaç: Bu çalışmada kronik solunum yetmezliği nedeni ile uzun dönem noninvaziv mekanik ventilasyon (NİMV) uygulanan ileri solumnum yetersizlikli KOAH hastalarının kalp hızı değişkenliği (KHD) araştırıldı. Hastalar ve Metod: Evde uzun dönem noktürnal NİMV kullanan sinüs ritminde 27 çok ağır KOAH hastası (58±8 yaş, 9 K) ile kontrol grubu olarak yaş ve cinsiyet olarak eşleştirilmiş solunum sıkıntısı olmayan 23 gönüllü (56±8 yaş, 11 K) çalışmaya alındı. Olgulara solunum fonksiyon testi, arter kan gazı analizi, transtorasik ekokardiyografi, 24 saatlik ambulatuvar elektrokardiyografi incelemesi yapıldı. Ambulatuvar EKG kaydında zaman-alan KHD analizi yapıldı. Bulgular: NİMV kullanırken hastaların %52'si NYHA fonksiyonel kapasite sınıf II, %36'sı sınıf III, %12'si sınıf IV idi. Hasta grubu yaş ve cins yönünden kontrol grubuyla benzerdi (her ikisi için de p>0.05). KOAH olgularının kalp hızı anlamlı yüksek (p0.05), sistolik pulmoner arter basıncı ise KOAH olgularında anlamlı olarak yüksek (p

Keywords

Kronik Obstriktif Akciğer Hastalığı, Noninvaziv Mekanik Ventilasyon, Kalp Hızı Değişkenliği.

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