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EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS

Year 2006, Volume: 10 Issue: 2, 26 - 28, 01.02.2006

Hasan Sunar Mahmut Yüksel Ahmet Salan Cavidan Arar Turan Ege Mevlüt Türe Ümit Halıcı Enver Duran

Abstract

Ventilation of the lungs during cardiopulmonary bypass may have a protective effect against postoperative lung injury Lung disturbances after cardiopulmonary bypass include pulmonary endothelial, interstitial and epithelial damage that can be demonstrated by Tc-99mlabeled diethylenetriamine pentaacetic acid inhalation scintigraphy. This study was conducted on 22 patients with on-pump coronary bypass operation. The study group n=9) received ventilation: respiratory rate 6 breaths/min, tidal volume 200 ml, and fraction of inspired oxygen 50% during extracorporeal circulation. The control group was not ventilated during CPB. Inhalation scintigraphy was performed to all patients preoperatively and postoperatively within the first week. Preoperative and postoperative median epithelial clearances of the ventilated group were 68.41 and 55.80 minutes, respectively. In the nonventilated group, preoperative and postoperative clearances were 84.20 and 82.29 minutes, respectively. In both groups, there was no significant difference between preoperative and postoperative values. The effect of ventilation may not be detectable via Tc-99m-labeled diethylenetriamine pentaacetic acid inhalation scintigraphy.

Keywords

Ventilation; Cardiopulmonary bypass; Tc 99m DTPA;Pulmonary epithelial permeability; Pulmonary scintigraphy

EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS

Year 2006, Volume: 10 Issue: 2, 26 - 28, 01.02.2006

Hasan Sunar Mahmut Yüksel Ahmet Salan Cavidan Arar Turan Ege Mevlüt Türe Ümit Halıcı Enver Duran

Abstract

Ventilation of the lungs during cardiopulmonary bypass may have a protective effect against postoperative lung injury Lung disturbances after cardiopulmonary bypass include pulmonary endothelial, interstitial and epithelial damage that can be demonstrated by Tc-99mlabeled diethylenetriamine pentaacetic acid inhalation scintigraphy. This study was conducted on 22 patients with on-pump coronary bypass operation. The study group n=9) received ventilation: respiratory rate 6 breaths/min, tidal volume 200 ml, and fraction of inspired oxygen 50% during extracorporeal circulation. The control group was not ventilated during CPB. Inhalation scintigraphy was performed to all patients preoperatively and postoperatively within the first week. Preoperative and postoperative median epithelial clearances of the ventilated group were 68.41 and 55.80 minutes, respectively. In the nonventilated group, preoperative and postoperative clearances were 84.20 and 82.29 minutes, respectively. In both groups, there was no significant difference between preoperative and postoperative values. The effect of ventilation may not be detectable via Tc-99m-labeled diethylenetriamine pentaacetic acid inhalation scintigraphy.

Keywords

Ventilation; Cardiopulmonary bypass; Tc 99m DTPA;Pulmonary epithelial permeability; Pulmonary scintigraphy

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Details

Primary Language Turkish
Journal Section Articles
Authors

Hasan Sunar This is me

Mahmut Yüksel This is me

Ahmet Salan This is me

Cavidan Arar This is me

Turan Ege This is me

Mevlüt Türe This is me

Ümit Halıcı This is me

Enver Duran This is me

Publication Date February 1, 2006
Published in Issue Year 2006 Volume: 10 Issue: 2

Cite

APA Sunar, H. ., Yüksel, M. ., Salan, A. ., Arar, C. ., et al. (2006). EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS. Koşuyolu Kalp Dergisi, 10(2), 26-28.
AMA Sunar H, Yüksel M, Salan A, Arar C, Ege T, Türe M, Halıcı Ü, Duran E. EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS. Koşuyolu Kalp Dergisi. February 2006;10(2):26-28.
Chicago Sunar, Hasan, Mahmut Yüksel, Ahmet Salan, Cavidan Arar, Turan Ege, Mevlüt Türe, Ümit Halıcı, and Enver Duran. “EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS”. Koşuyolu Kalp Dergisi 10, no. 2 (February 2006): 26-28.
EndNote Sunar H, Yüksel M, Salan A, Arar C, Ege T, Türe M, Halıcı Ü, Duran E (February 1, 2006) EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS. Koşuyolu Kalp Dergisi 10 2 26–28.
IEEE H. . Sunar, M. . Yüksel, A. . Salan, C. . Arar, T. . Ege, M. . Türe, Ü. . Halıcı, and E. . Duran, “EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS”, Koşuyolu Kalp Dergisi, vol. 10, no. 2, pp. 26–28, 2006.
ISNAD Sunar, Hasan et al. “EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS”. Koşuyolu Kalp Dergisi 10/2 (February 2006), 26-28.
JAMA Sunar H, Yüksel M, Salan A, Arar C, Ege T, Türe M, Halıcı Ü, Duran E. EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS. Koşuyolu Kalp Dergisi. 2006;10:26–28.
MLA Sunar, Hasan et al. “EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS”. Koşuyolu Kalp Dergisi, vol. 10, no. 2, 2006, pp. 26-28.
Vancouver Sunar H, Yüksel M, Salan A, Arar C, Ege T, Türe M, Halıcı Ü, Duran E. EFFECT OF VENTILATION ON PULMONARY EPITHELIAL PERMEABILITY DURING CARDIOPULMONARY BYPASS. Koşuyolu Kalp Dergisi. 2006;10(2):26-8.