Gama Işınları ile Işınlanmış Yeni Bir Isoquinoline Sulfonamide (C17H20BrNO3S) Maddesinin X-Bant EPR Çalışması

Year 2020, Volume: 8 , 46 - 52, 31.12.2020

Özgül Karataş , Yusuf Ceylan

https://doi.org/10.36306/konjes.821866

Cited By: 1

Abstract

Kaynaşık bir heteroksil bileşiği olan yeni epoxyisoquinoline sulfonamide maddesi (I), (4aS,7S,8aR)-8a-bromo-7-methyl-2-tosyl-2,3,4,7,8,8a-hexahydro-1H-4a,7-epoxyisoquinoline, yeşil ve kademeli bir süreç ile sentezlendi. Daha sonra doz hızı of 0.981 kGy/h olan 60Co-gama () kaynağı ile oda sıcaklığında 72 saat ışınlandı. I bileşiğinin EPR spektrumları, 150-340 K sıcaklık aralığında X-bant EPR spektrometresi kullanılarak manyetik alanda üç farklı yönelimde kaydedildi. Elde edilen sonuçlara göre, örneğe ait izotropik spektrumların olduğu görüldü ve C ̇H_3 H radikalinin varlığı gözlemlendi. Sonuçlar, Bruker WinEPR-Simfonia programı kullanılarak fit edildi. Radikalin aşırı ince yapı sabiti (A) ile deneysel izotropik spektroskopik değeri (g) hesaplandı.

Keywords

EPR, Işınlama Etkileri, Radikal, Sentez, Sulfonamide

X-BAND EPR STUDIES OF GAMMA IRRADIATED A NEW ISOQUINOLINE SULFONAMIDE: C17H20BrNO3S

Abstract

A new epoxyisoquinoline sulfonamide as a fused heterocycle compound (I), (4aS,7S,8aR)-8a-bromo-7-methyl-2-tosyl-2,3,4,7,8,8a-hexahydro-1H-4a,7-epoxyisoquinoline was synthesized using green and cascade progress which was then irradiated by 60Co-gamma () ray source with a dose speed of 0.981 kGy/h at the room temperature for 72h. EPR spectra of I compound were measured at different orientations in magnetic field with X-band EPR spectrometer along the temperatures between 150-340 K. Isotropic spectrum was obtained without depending on temperature and radical structure, C ̇H_3 H was observed. Radical was simulated using the Bruker software WinEPR-Simfonia and the experimental isotropic g-value with hyperfine coupling constant of radical was calculated.

Keywords

EPR, Irradiation effects, Radical, Synthesis, Sulfonamide

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