Sekonder Progresif Multipl Sklerozun Tedavisinde Olası Biyomedikal Çözüm Önerileri

Year 2022, Volume: 5 Issue: 2, 32 - 40, 31.12.2022

Özcan Gündoğdu , Halenur Çelik , Sevim Şahin

https://doi.org/10.53410/koufbd.872274

Abstract

Multipl Skleroz (MS), vücudun bağışıklık sistemi hücreleri tarafından beyindeki sinir hücrelerinin dış kısmında bulunan miyelin kılıfların zarar görmesi sonucu lezyon veya plak oluşmasına bağlı nörolojik bir hastalıktır. Bu makalenin amacı Sekonder Progresif MS (SPMS) için tıp ve biyomedikal mühendisliği alanında çözüm önerileri üreterek yapılan çalışmaların anlatılmasıdır. Hastalığın tıp alanında çeşitli tedavi yöntemleri vardır. MS tedavisi kişiye özel olarak yapılmaktadır. Tıp alanında yapılan en temel tedavi yöntemi ilaç ile tedavidir. Son yapılan çalışmalar sonucunda nanoparçacıkların polimerik yapısının içerisine konulan miyelin antijenleri sayesinde bağışıklık sistemi hücrelerinin miyelinli hücrelere saldırması engellenerek hastalığın yavaşlatılması sağlanmıştır. Zarar gören miyelin kılıfların onarımı ise kolesterolün düşürülmesinde kullanılan bir molekül sayesinde yapılmıştır. MS tam olarak nedeni bilinmeyen otoimmün ve nörolojik bir hastalıktır. Bu makale çalışmasında ise yapılmış olan deneysel çalışmalara göre üretilen tüm çözüm önerilerinin derlenmesi amaçlanmıştır.

Keywords

Bağışıklık Sistemi, Miyelin Kılıf, Multipl Skleroz, Nanoparçacık, Sinir Hücreleri

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