COMORBIDITY BETWEEN BIPOLAR AFFECTIVE DISORDER AND OBSESSIVE COMPULSIVE DISORDER

Abstract

Bipolar affective disorder (BPD) is a chronic mood disorder which impair functionality of the patient severely. Itincludes mania, hypomania, anddepressionepisodes. Obsessive-compulsive disorder (OCD) is a disorder marked by obsessions and compulsions. Obsessions are repetitive and involuntary thoughts distressing the patient severely and compulsions are repetitive actions o rthoughts reducing the impact of the obsessions. Some researchers consider that similar pathogenesis cause both disorders. Although similar pathogenesis theory hasn’t been proven comorbidity between these disorders are common. BPD and OCD both impair the functionality significantly. Comorbidity between these disorders also impair functionality of the patient causin gprolonged duration of disease, affecting clinical course, and impairing treatment compliance of the patients. Relationship between thedisordes are complicated and detailed assesment should be made to decide on medical treatment. In this review it was aimed to highlight the comorbid disorders of BPD and OCD, to revise the effect of comorbidity between BPD and OCD on the clinical course.An other aim was to mention the treatment options in comorbid cases

Keywords

• Bipolar affective disorder, obsessive compulsive disorder, comorbidity

Bipolar duygudurum bozukluğu ve obsesif kompülsif bozukluk ilişkisi

Öz

Bipolar duygudurum bozukluğu (BDB) depresyon, hipomani ve mani dönemlerinin görüldüğü işlevselliği önemli derecede bozan, kronik seyirli bir duygudurum bozukluğudur. Obsesif kompülsif bozukluk (OKB) ise tekrarlayıcı ve istem dışı akla gelen, kişinin sıkıntı duymasına yol açan düşünceler olan obsesyonlar ile bu obsesyonların etkisini azaltmaya yarayan düşünceler ve davranışlar olan kompülsiyonlarla seyreden bir bozukluktur.Bu iki hastalık arasında etyolojik bir ilişki olabileceğini savunan araştırmacılar bulunmaktadır. Bu henüz geçerlilik kazanmış bir teori olmasa da iki hastalığın eş tanı sıklığı yüksektir. Hem BDB hem de OKB işlevselliği önemli düzeyde bozan hastalıklar olup; iki hastalığın eş tanısında klinik seyir değişmekte, hastalık süresi uzamakta ve hastaların tedaviye uyumu bozulmaktadır. İki hastalık arasındaki ilişki komplekstir ve eş tanı durumlarında medikal tedaviye karar verirken ayrıntılı değerlendirme yapılması gerekmektedir. Bu gözden geçirme çalışmasında BDB ve OKB’de sık görülen eş tanıları, her iki hastalığın eş tanı durumlarında klinik seyir değişikliklerini vurgulamak ve eş tanı durumlarında tedavi seçeneklerini belirtmek amaçlanmıştır.

Anahtar Kelimeler

• Bipolar bozukluk, obsesif kompülsif bozukluk, komorbidite

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