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Colchicine treatment in recurrent subacute thyroiditis after Covid-19 and mRNA vaccination

Year 2025, Volume: 1 Issue: 1, 1 - 3, 21.04.2025

Abstract

Subacute thyroiditis (SAT) is an inflammatory disease of the thyroid gland. It usually develops after a viral upper respiratory infection. It is often self-limited, but about 20% of cases are refractory to treatment with steroids. Steroid therapy is the first line of treatment for recurrent episodes of SAT. This letter reports that colchicine may be beneficial in two cases of recurrent SAT after covid-19 infection and mRNA vaccination.

References

  • 1.Brancatella, A., Ricci, D., Viola, N., Sgrò, D., Santini, F., & Latrofa, F. (2020). Subacute Thyroiditis After Sars-COV-2 Infection. The Journal of clinical endocrinology and metabolism, 105(7), dgaa276. https://doi.org/10.1210/clinem/dgaa276
  • 2.İremli, B. G., Şendur, S. N., & Ünlütürk, U. (2021). Three Cases of Subacute Thyroiditis Following SARS-CoV-2 Vaccine: Postvaccination ASIA Syndrome. The Journal of clinical endocrinology and metabolism, 106(9), 2600–2605. https://doi.org/10.1210/clinem/dgab373
  • 3.Tian, Z., Su, Y., Zhang, M., Zhang, X., & Guan, Q. (2020). Successful Management of Recurrent Subacute Thyroiditis by Adding Colchicine to Glucocorticoid Treatment: A Case Series Study. Hormone and metabolic research, 52(10), 712–717. https://doi.org/10.1055/a-1148-2260
  • 4.Bahçecioğlu, A. B., & Erdoğan, M. F. (2024). Colchicine as a Steroid-Sparing Agent in Relapsing and Steroid-Dependent Subacute Thyroiditis: Preliminary Observations. Thyroid : official journal of the American Thyroid Association, 34(11), 1444–1446

Covid-19 ve mRNA aşılaması sonrası tekrarlayan subakut tiroiditte kolşisin tedavisi

Year 2025, Volume: 1 Issue: 1, 1 - 3, 21.04.2025

Abstract

Subakut tiroidit (SAT), tiroid bezinin inflamatuvar bir hastalığıdır. Genellikle viral bir üst solunum yolu enfeksiyonundan sonra gelişir. Genellikle kendi kendini sınırlar, ancak vakaların yaklaşık %20'si steroid tedavisine dirençlidir. Steroid tedavisi, tekrarlayan SAT atakları için ilk tedavi yöntemidir. Bu mektupta, covid-19 enfeksiyonu ve mRNA aşılamasından sonra tekrarlayan iki SAT vakasında kolşisinin faydalı olabileceği bildirilmektedir.

References

  • 1.Brancatella, A., Ricci, D., Viola, N., Sgrò, D., Santini, F., & Latrofa, F. (2020). Subacute Thyroiditis After Sars-COV-2 Infection. The Journal of clinical endocrinology and metabolism, 105(7), dgaa276. https://doi.org/10.1210/clinem/dgaa276
  • 2.İremli, B. G., Şendur, S. N., & Ünlütürk, U. (2021). Three Cases of Subacute Thyroiditis Following SARS-CoV-2 Vaccine: Postvaccination ASIA Syndrome. The Journal of clinical endocrinology and metabolism, 106(9), 2600–2605. https://doi.org/10.1210/clinem/dgab373
  • 3.Tian, Z., Su, Y., Zhang, M., Zhang, X., & Guan, Q. (2020). Successful Management of Recurrent Subacute Thyroiditis by Adding Colchicine to Glucocorticoid Treatment: A Case Series Study. Hormone and metabolic research, 52(10), 712–717. https://doi.org/10.1055/a-1148-2260
  • 4.Bahçecioğlu, A. B., & Erdoğan, M. F. (2024). Colchicine as a Steroid-Sparing Agent in Relapsing and Steroid-Dependent Subacute Thyroiditis: Preliminary Observations. Thyroid : official journal of the American Thyroid Association, 34(11), 1444–1446
There are 4 citations in total.

Details

Primary Language English
Subjects Endocrinology
Journal Section Letter to Editor
Authors

Ayten Oğuz

Murat Şahin

Publication Date April 21, 2025
Submission Date March 12, 2025
Acceptance Date March 27, 2025
Published in Issue Year 2025 Volume: 1 Issue: 1

Cite

APA Oğuz, A., & Şahin, M. (2025). Colchicine treatment in recurrent subacute thyroiditis after Covid-19 and mRNA vaccination. Kahramanmaraş Sütçü İmam Üniversitesi Sağlık Bilimleri Dergisi, 1(1), 1-3.