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Lidokain Toksisitesinin Lipid Emülsiyonu ile Başarılı Tedavisi

Year 2017, Volume: 5 Issue: 1, 36 - 40, 15.01.2017

Abstract

Bu bildiride, port katater takılması için yüksek doz ve volümde lidokain infiltrasyonu

uygulaması sonrasında ani toksisite bulguları gösteren 28 yaşındaki ASA II kadın

hasta sunulmaktadır. Literatürdeki olgulardan farklı olarak, lidokain toksisitesi santral

veya periferik blok tekniği uygulamadan gelişti. Sistemik toksisite nedeniyle bilinci kapanan

ve ventriküler taşikardi gelişen hasta olası bir kardiyak arrest meydana gelmeden

acil lipid emulsiyonu başlanmasıyla başarıyla tedavi edildi. Lipid tedavisi sonrasında bilinci

açılan hasta nefes almakta güclük çektiğini bildirdi. Çekilen akciğer grafisi sonrasında

kateter takma işlemi sırasında komplikasyon geliştiği fark edildi ve hastaya pnömotoraks

tanısı konuldu.

Lokal anestezik toksisitesi gelişen olguların resüsitasyonunda lipid tedavisinin hayat

kurtarıcı öneminin olduğu ve ameliyathane, yoğun bakım ve acil serviste resüsitasyon

gereçlerinin yanında lipid infüzyonu için kullanılacak preparatların hazır bulundurulmasının





















gerektiği kanısındayız.

References

  • 1. Schroeder H. [Temporary bilateral blindness after acute lidocaine toxicity]. Anesth Analg 2002; 95(1): 224-226.
  • 2. Weinberg GL, VadeBoncouer T, Ramaraju GA, Garcia-Amaro MF, Cwik MJ. [Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats]. Anesthesiology 1998; 88 (4):1071–1075 .
  • 3. Rosenblatt MA, Abel M, Fischer GW, Itzkovich CJ, Eisenkraft JB. [Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest]. Anesthesiology 2006; 105(1):217–218.
  • 4. Litz RJ, Popp M, Stehr SN, Koch T. [Successful resuscitation of a patient with ropivacaineinduced asystole after axillary plexus block using lipid infusion]. Anaesthesia 2006; 61(8):800–801.
  • 5. Sharma R, Goel N, Kumar A, Panda A. [Central nervous system toxicity with a 1 mL lidocaine injection in the aberrant carotid artery overlying the trachea]. Acta Anaesthesiol Scand 2008;52(10):1436.
  • 6. Zausig YA, Zink W, Keil M, Siner B, Barwing J, Wiese CHR et al. [Lipid emulsion improves recovery from bupivacaine-induced cardiac arrest, but not from ropivacaine- or mepivacaine-induced cardiac arrest]. Regional Anesthesia 2009; 109(4):1323–1326.
  • 7. Weinberg GL. [ Lipid infusion therapy: translation to clinical practice]. Anesth Analg 2008;106 (5):1340–1342.
  • 8. Weinberg GL, Di Gregorio G, Ripper R, Kelly K, Massad M, Edelman L et al. [Resuscitation with lipid versus epinephrine in a rat model of bupivacaine overdose]. Anesthesiology 2008;108 (5):907–913.
  • 9. Satsumae T, Tanaka M, Saito S, Inomata S. [Convulsions after ropivacaine 300 mg for brachial plexus block]. Br J Anaesth 2008;101(6):860-862. 10. Özyuvacı E, Kutlu F. [Totally implantable venous access devices via subclavian vein: a retrospective study of 368 oncology patients]. Adv Ther 2006; 23(4):574-581.
  • 11. Weinberg G, Ripper R, Feinstein DL, Hoffman W. [ Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity]. Reg Anesth Pain Med 2003, 28(3):198-202.
  • 12. Ludot H, Tharin JY, Belouadah M, Mazoit JX, Malinovsky JM. [Successful resuscitation after ropivacaine and lidocaine-induced ventricular arrhythmia following posterior lumbar plexus block in a child]. Anesth Analg 2008;106(5):1572-1574.
  • 13. Warren J, Thoma RB, Georgescu A, Saurin S. [Intravenous lipid infusion in the successful resuscitation of local anesthetic-induced cardiovascular collapse after supraclavicular brachial plexus block]. Anesth Analg. 2008; 106(5):1578–1580.
  • 14. Litz RJ, Roessel T, Heller AR, Stehr SN. [Reversal of central nervous system and cardiac toxicity afterlocal anesthetic intoxication by lipid emulsion injection]. Anesth Analg 2008; 106(5):1575-1577.
  • 15. Picard J, Ward SC, Zumpe R, Meek T, Barlow J, Harrop-Griffiths W. [Guidelines and the adoption of 'lipid rescue' therapy for local anaesthetic toxicity]. Anaesthesia. 2009; 64(2):122-125.
  • 16. Neal JM, Bernards CM, Butterworth JF 4th, Di Gregorio G, Drasner K, Hejtmanek MR et al. [ASRA practice advisory on local anesthetic systemic toxicity]. Reg Anesth Pain Med. 2010; 35(2):152-161.
  • 17. Leskiw U, Weinberg GL. [Lipid resuscitation for local anesthetic toxicity: is it really lifesaving? ]. Curr Opin Anaesthesiol. 2009; 22(5): 667-671.
  • 18. Foxall G, McCahon R, Lamb J, Hardman JG, Bedforth NM. [Levobupivacaine- induced seizures and cardiovascular collapse treated with Intralipid ]. Anaesthesia 2007; 62(5): 516-518.
  • 19. Markowitz S, Neal JM. [Immediate lipid emulsion therapy in the successful treatment of bupivacaine systemic toxicity]. Reg Anesth Pain Med 2009; 34(3):276.
  • 20. Sonsino DH, Fischler M. [Immediate intravenous lipid infusion in the successful resuscitation of ropivacaine-induced cardiac arrest after infraclavicular brachial plexus block]. Reg Anesth Pain Med 2009;34(3):276-277.
  • 21. Charbonneau H, Marcou TA, Mazoit JX, Zetlaoui PJ, Benhamou D. [Early use of lipid emulsion to treat incipient mepivacaine intoxication]. Reg Anesth Pain Med 2009; 34(3):277-278.
  • 22. Gnaho A, Eyrieux S, Gentili M. [Cardiac arrest during an ultrasound- guided sciatic nerve block combined with nerve stimulation]. Reg Anesth Pain Med 2009; 34(3):278.
Year 2017, Volume: 5 Issue: 1, 36 - 40, 15.01.2017

Abstract

References

  • 1. Schroeder H. [Temporary bilateral blindness after acute lidocaine toxicity]. Anesth Analg 2002; 95(1): 224-226.
  • 2. Weinberg GL, VadeBoncouer T, Ramaraju GA, Garcia-Amaro MF, Cwik MJ. [Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats]. Anesthesiology 1998; 88 (4):1071–1075 .
  • 3. Rosenblatt MA, Abel M, Fischer GW, Itzkovich CJ, Eisenkraft JB. [Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest]. Anesthesiology 2006; 105(1):217–218.
  • 4. Litz RJ, Popp M, Stehr SN, Koch T. [Successful resuscitation of a patient with ropivacaineinduced asystole after axillary plexus block using lipid infusion]. Anaesthesia 2006; 61(8):800–801.
  • 5. Sharma R, Goel N, Kumar A, Panda A. [Central nervous system toxicity with a 1 mL lidocaine injection in the aberrant carotid artery overlying the trachea]. Acta Anaesthesiol Scand 2008;52(10):1436.
  • 6. Zausig YA, Zink W, Keil M, Siner B, Barwing J, Wiese CHR et al. [Lipid emulsion improves recovery from bupivacaine-induced cardiac arrest, but not from ropivacaine- or mepivacaine-induced cardiac arrest]. Regional Anesthesia 2009; 109(4):1323–1326.
  • 7. Weinberg GL. [ Lipid infusion therapy: translation to clinical practice]. Anesth Analg 2008;106 (5):1340–1342.
  • 8. Weinberg GL, Di Gregorio G, Ripper R, Kelly K, Massad M, Edelman L et al. [Resuscitation with lipid versus epinephrine in a rat model of bupivacaine overdose]. Anesthesiology 2008;108 (5):907–913.
  • 9. Satsumae T, Tanaka M, Saito S, Inomata S. [Convulsions after ropivacaine 300 mg for brachial plexus block]. Br J Anaesth 2008;101(6):860-862. 10. Özyuvacı E, Kutlu F. [Totally implantable venous access devices via subclavian vein: a retrospective study of 368 oncology patients]. Adv Ther 2006; 23(4):574-581.
  • 11. Weinberg G, Ripper R, Feinstein DL, Hoffman W. [ Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity]. Reg Anesth Pain Med 2003, 28(3):198-202.
  • 12. Ludot H, Tharin JY, Belouadah M, Mazoit JX, Malinovsky JM. [Successful resuscitation after ropivacaine and lidocaine-induced ventricular arrhythmia following posterior lumbar plexus block in a child]. Anesth Analg 2008;106(5):1572-1574.
  • 13. Warren J, Thoma RB, Georgescu A, Saurin S. [Intravenous lipid infusion in the successful resuscitation of local anesthetic-induced cardiovascular collapse after supraclavicular brachial plexus block]. Anesth Analg. 2008; 106(5):1578–1580.
  • 14. Litz RJ, Roessel T, Heller AR, Stehr SN. [Reversal of central nervous system and cardiac toxicity afterlocal anesthetic intoxication by lipid emulsion injection]. Anesth Analg 2008; 106(5):1575-1577.
  • 15. Picard J, Ward SC, Zumpe R, Meek T, Barlow J, Harrop-Griffiths W. [Guidelines and the adoption of 'lipid rescue' therapy for local anaesthetic toxicity]. Anaesthesia. 2009; 64(2):122-125.
  • 16. Neal JM, Bernards CM, Butterworth JF 4th, Di Gregorio G, Drasner K, Hejtmanek MR et al. [ASRA practice advisory on local anesthetic systemic toxicity]. Reg Anesth Pain Med. 2010; 35(2):152-161.
  • 17. Leskiw U, Weinberg GL. [Lipid resuscitation for local anesthetic toxicity: is it really lifesaving? ]. Curr Opin Anaesthesiol. 2009; 22(5): 667-671.
  • 18. Foxall G, McCahon R, Lamb J, Hardman JG, Bedforth NM. [Levobupivacaine- induced seizures and cardiovascular collapse treated with Intralipid ]. Anaesthesia 2007; 62(5): 516-518.
  • 19. Markowitz S, Neal JM. [Immediate lipid emulsion therapy in the successful treatment of bupivacaine systemic toxicity]. Reg Anesth Pain Med 2009; 34(3):276.
  • 20. Sonsino DH, Fischler M. [Immediate intravenous lipid infusion in the successful resuscitation of ropivacaine-induced cardiac arrest after infraclavicular brachial plexus block]. Reg Anesth Pain Med 2009;34(3):276-277.
  • 21. Charbonneau H, Marcou TA, Mazoit JX, Zetlaoui PJ, Benhamou D. [Early use of lipid emulsion to treat incipient mepivacaine intoxication]. Reg Anesth Pain Med 2009; 34(3):277-278.
  • 22. Gnaho A, Eyrieux S, Gentili M. [Cardiac arrest during an ultrasound- guided sciatic nerve block combined with nerve stimulation]. Reg Anesth Pain Med 2009; 34(3):278.
There are 21 citations in total.

Details

Journal Section Makaleler 1
Authors

Demet Sergin

Publication Date January 15, 2017
Published in Issue Year 2017 Volume: 5 Issue: 1

Cite

APA Sergin, D. (2017). Lidokain Toksisitesinin Lipid Emülsiyonu ile Başarılı Tedavisi. Klinik Tıp Bilimleri, 5(1), 36-40.
AMA Sergin D. Lidokain Toksisitesinin Lipid Emülsiyonu ile Başarılı Tedavisi. Klinik Tıp Bilimleri. January 2017;5(1):36-40.
Chicago Sergin, Demet. “Lidokain Toksisitesinin Lipid Emülsiyonu Ile Başarılı Tedavisi”. Klinik Tıp Bilimleri 5, no. 1 (January 2017): 36-40.
EndNote Sergin D (January 1, 2017) Lidokain Toksisitesinin Lipid Emülsiyonu ile Başarılı Tedavisi. Klinik Tıp Bilimleri 5 1 36–40.
IEEE D. Sergin, “Lidokain Toksisitesinin Lipid Emülsiyonu ile Başarılı Tedavisi”, Klinik Tıp Bilimleri, vol. 5, no. 1, pp. 36–40, 2017.
ISNAD Sergin, Demet. “Lidokain Toksisitesinin Lipid Emülsiyonu Ile Başarılı Tedavisi”. Klinik Tıp Bilimleri 5/1 (January 2017), 36-40.
JAMA Sergin D. Lidokain Toksisitesinin Lipid Emülsiyonu ile Başarılı Tedavisi. Klinik Tıp Bilimleri. 2017;5:36–40.
MLA Sergin, Demet. “Lidokain Toksisitesinin Lipid Emülsiyonu Ile Başarılı Tedavisi”. Klinik Tıp Bilimleri, vol. 5, no. 1, 2017, pp. 36-40.
Vancouver Sergin D. Lidokain Toksisitesinin Lipid Emülsiyonu ile Başarılı Tedavisi. Klinik Tıp Bilimleri. 2017;5(1):36-40.