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Relationship of the labour process with hormone physiology and midwife-led care

Yıl 2024, Cilt: 5 Sayı: 3, 286 - 302, 28.12.2024
https://doi.org/10.59244/ktokusbd.1564292

Öz

The labour process and the well-being of the mother and fetus/newborn in the early postpartum period are closely associated with hormone physiology. Oxytocin, beta-endorphin, prolactin and stress hormones play an effective role in the labour process. Besides, melatonin is considered to be another hormone that affects labour. Natural childbirth can be realized by the harmonious and synergistic release of hormones. Therefore, factors causing the mother to experience stress and fear can disrupt hormonal physiology, which potentially increases the mother’s perceived level of pain. This condition could negatively affect the progress of labour as well as the physical and psychological health of the mother and the fetus/newborn. If the labour process is managed using appropriate care practices and strategies, the woman's release of stress hormones decreases and beta-endorphin release increases. Tolerated stress hormones positively affect the natural progression of labour, the effects of oxytocin and melatonin, and their compatibility with each other. This harmony helps to cope with labour pain. In this way, the labour process is not interrupted and the labour progress is positively affected. Midwife-led care practices are highly important in terms of promoting, protecting, and supporting this positive cycle. This review discusses the hormones that are effective in the labour process, the relationship of these hormones with each other, and recommendations for midwife-led care practices.

Kaynakça

  • Abd El-Aziz, S. N., Mansour, S., & Hassan, N. F. (2017). Factors associated with fear of childbirth: It’s effect on women’s preference for elective cesarean section. Journal of Nursing Education Practice, 7(1), 133-46. http://dx.doi.org/10.5430/jnep.v7n1p133
  • Aktas, S., & Pasinlioğlu, T. (2021). The effect of empathy training given to midwives on the empathic communication skills of midwives and the birth satisfaction of mothers giving birth with the help of these midwives: A quasi‐experimental study. Journal of Evaluation in Clinical Practice, 27(4), 858- 867. https://doi.org/10.1111/jep.13523
  • American College of Obstetricians and Gynecologists (ACOG). (2016). Prevention and management of obstetric lacerations at vaginal delivery. Obstetrics & Gynecology, 128(1), e1–e15. https://doi.org/10.1097/AOG.0000000000001523
  • American College of Obstetricians and Gynecologists (ACOG). (2019). Approaches to limitintervention in labor and birth. Obstetrics & Gynecology, 133(2), e164–e173. https://doi.org/10.1097/aog.0000000000003074
  • Aune, I., Torvik, H. M., Selboe, S. T., Skogås, A. K., Persen, J., & Dahlberg, U. (2015). Promoting a normal birth and a positive birth experience—Norwegian women׳ s perspectives. Midwifery, 31(7), 721-727. https://doi.org/10.1016/j.midw.2015.03.016
  • Ayres-de-Campos, D., Simon, A., Modi, N., Tudose, M., Saliba, E., Wielgos, M., ... & Jacobsson, B. (2024). European Association of Perinatal Medicine (EAPM) European Midwives Association (EMA) Joint position statement: Caesarean delivery rates at a country level should be in the 15-20% range. European Journal of Obstetrics & Gynecology and Reproductive Biology, 294, 76-78. https://doi.org/10.1016/j.ejogrb.2024.01.005.
  • Barus, E. B., & Massi, N. (2020). Cortisol levels and labor outcomes among women in the third trimester of pregnancy. Enfermería Clínica, 30 (2), 487-490. https://doi.org/10.1016/j.enfcli.2019.07.144
  • Benfield, R. D., Hortobagyi, T., Tanner, C. J., Swanson, M., Heitkem- per, M. M., & Newton, E. R. (2010). The effects of hydrotherapy on anxiety, pain, neuroendocrine responses, and contraction dynamics during labor. Biological Research for Nursing, 12(1), 28–36. http://dx.doi.org/10.1177/1099800410361535
  • Bleker, L. S., Roseboom, T. J., Vrijkotte, T. G., Reynolds, R. M., & de Rooij, S. R. (2017). Determinants of cortisol during pregnancy–The ABCD cohort. Psychoneuroendocrinology, 83 (1), 172-181. https://doi.org/10.1016/j.psyneuen.2017.05.026.
  • Buckley, S. J. (2015). Executive summary of hormonal physiology of childbearing: evidence and implications for women, babies, and maternity care. The Journal of Perinatal Education, 24(3), 145-153. https://doi.org/10.1891/1058-1243.24.3.145
  • Carlomagno, G., Minini, M., Tilotta, M., & Unfer, V. (2018). From implantation to birth: insight into molecular melatonin functions. International Journal of Molecular Sciences, 19(9), 2802. https://doi.org/10.3390/ijms19092802
  • de Brito Pitilin, E., Gasparin, V. A., Bagatini, M. D., & Lentsck, M. H. (2020). Determinants of the prolactin level in immediate postpartum women. Cogitare Enferm, 25, e71511. http://dx.doi.org/10.5380/ce.v25i0.71511.
  • Dick-Read, G. (2006). S. Childbirth Without Fear: The Principles and Practice of Natural Childbirth. London: Pollinger Limited. Sayfa 130-140.
  • Flores-Espinosa, P., Méndez, I., Irles, C., Olmos-Ortiz, A., Helguera-Repetto, C., Mancilla-Herrera, I. Ortuño-Sahagún, D., Goffin, V.,Zaga-Clavellina, V. (2023). Immunomodulatory role of decidual prolactin on the human fetal membranes and placenta. Frontiers in Immunology, 14, 1212736. https://doi.org/10.3389/fimmu.2023.1212736.
  • Hammond, A., Foureur, M., Homer, C. S., & Davis, D. (2013). Space, place and the midwife: Exploring the relationship between the birth environment, neurobiology and midwifery practice. Women and Birth, 26(4), 277-281. https://doi.org/10.1016/j.wombi.2013.09.001.
  • Hundley, V., Downe, S., & Buckley, S. J. (2020). The initiation of labour at term gestation: Physiology and practice implications. Best Practice & Research Clinical Obstetrics & Gynaecology, 67, 4-18. https://doi.org/10.1016/j.bpobgyn.2020.02.006.
  • Kenkel, W. 2021. Birth signalling hormones and the developmental consequences of caesarean delivery. Journal of Neuroendocrinology, 33(1), e12912. https://doi.org/10.1111/jne.12912
  • Goemaes, R., Beeckman, D., Verhaeghe, S., & Van Hecke, A. (2020). Sustaining the quality of midwifery practice in Belgium: Challenges and opportunities for advanced midwife practitioners. Midwifery, 89, 102792. https://doi.org/10.1016/j.midw.2020.102792.
  • Lawot, I., & Sharma, P. K. (2023). Effects of non-pharmacological methods on reduction labor pain among primiparous women: A Review. International Journal of Innovative Science and Research Technology, 8(7), 2456-2165. https://doi.org/10.38124/ijisrt/IJISRT23JUL11204.
  • Lorentzen, I. P., Andersen, C. S., Jensen, H. S., Fogsgaard, A., Foureur, M., Lauszus, F. F., & Nohr, E. A. (2021). Does giving birth in a “birth environment room” versus a standard birth room lower augmentation of labor?–Results from a randomized controlled trial. European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 10, 100125. https://doi.org/10.1016/j.eurox.2021.100125.
  • McCarthy, R., Jungheim, E. S., Fay, J. C., Bates, K., Herzog, E. D., & England, S. K. (2019). Riding the rhythm of melatonin through pregnancy to deliver on time. Frontiers in endocrinology, 10, 464826. https://doi.org/10.3389/fendo.2019.00616.
  • Mete, S. (2013). Stres, hormonlar ve doğum arasındaki ilişki. Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi, 6(2), 93-98.
  • Organisation for Economic Co-Operation and Development (OECD). 2020. ‘‘Caesarean sections (indicator)’’. https://doi: 10.1787/adc3c39f-en. Erişim tarihi; 17 Şubat 2024.
  • Rana, M., Jain, S., & Choubey, P. (2022). Prolactin and its significance in the placenta. Hormones, 21(2), 209-219. https://doi.org/10.1007/s42000-022-00373-y.
  • Reiter, R. J., Sharma, R., Chuffa, L. G. D., Zuccari, D. A., Amaral, F. G., & Cipolla-Neto, J. (2024). Melatonin-mediated actions and circadian functions that improve implantation, fetal health and pregnancy outcome. Reproductive Toxicology,124 (4), 108534. https://doi.org/10.1016/j.reprotox.2024.108534.
  • Rusnawati, M. S., Chalid, M. T., Saleh, A., Mappaware, N. A., Saidah Syamsuddin, J. J., Nur, A., & Halisah, A. T. (2024). Effectiveness Of The Application Of Respectful Midwifery Care On Prostaglandin (Pge2) Levels And Maternal Pain Perception Level In Normal Childbirth. Pakistan Journal of Life and Social Sciences, 22(2), 348-354. https://doi.org/10.57239/PJLSS-2024-22.2.0025.
  • Sakala, C., Romano, A. M., & Buckley, S. J. (2016). Hormonal physiology of childbearing, an essential framework for maternal–newborn nursing. Journal of Obstetric, Gynecologic & Neonatal Nursing, 45(2), 264-275. https://doi.org/10.1016/j.jogn.2015.12.006.
  • Sayiner, F. D., Öztürk, D. M., Ulupinar, E., Velipasaoglu, M., & Corumlu, E. P. (2021). Stress caused by environmental effects on the birth process and some of the labor hormones at rats: ideal birth environment and hormones. The journal of Maternal-Fetal & Neonatal Medicine, 34(16), 2600-2608. https://doi.org/10.1080/14767058.2019.1670162.
  • Stark, M. A., Remynse, M., & Zwelling, E. (2016). Importance of the birth environment to support physiologic birth. Journal of Obstetric, Gynecologic & Neonatal Nursing, 45(2), 285-294. https://doi.org/10.1016/j.jogn.2015.12.008
  • Stjernholm, Y. V., Nyberg, A., Cardell, M., & Höybye, C. (2016). Circulating maternal cortisol levels during vaginal delivery and elective cesarean section. Archives of Gynecology and Obstetrics, 294, 267 271. https://doi.org/10.1007/s00404-015-3981-x
  • Striebich, S., Mattern, E., and Ayerle, G. M. (2018). Support for pregnant women identified with fear of childbirth (DK)/tokophobia - A systematic review of approaches and interventions. Midwifery , 61 , 97-115. https://doi.org/10.1016/j.midw.2018.02.013.
  • Sulu, R., Akbas, M., & Cetiner, S. (2022). Effects of transcutaneous electrical nerve stimulation applied at different frequencies during labor on hormone levels, labor pain perception, and anxiety: A randomized placebo-controlled single-blind clinical trial. European Journal of Integrative Medicine, 52, 102124. https://doi.org/10.1016/j.eujim.2022.102124.
  • The United Nations (UN). (2017). ‘’The Sustainable development goals report 2017’’. The United Nations, New York, 20-24. https://unstats.un.org/sdgs/files/report/2017/thesustainabledevelopmentgoalsreport2017.pdf Son erişim tarihi: 03 Ocak 2024.
  • Türkiye Nüfus ve Sağlık Araştırması (TNSA). (2018). http://www.hips.hacettepe.edu.tr/tnsa2018/rapor/TNSA2018_ana_Rapor.pdf. Erişim tarihi; 17 Şubat 2024.
  • Uvnäs-Moberg, K. (2024). The physiology and pharmacology of oxytocin in labor and in the peripartum period. American Journal of Obstetrics and Gynecology, 230(3), S740-S758. https://doi.org/10.1016/j.ajog.2023.04.011
  • Verteramo, R., Pierdomenico, M., Greco, P., & Milano, C. (2022). The role of melatonin in pregnancy and the health benefits for the newborn. Biomedicines, 10(12), 3252. https://doi.org/10.3390/biomedicines10123252.
  • Vittner, D., McGrath, J., Robinson, J., Lawhon, G., Cusson, R., Eisenfeld, L., ... & Cong, X. (2018). Increase in oxytocin from skin-to-skin contact enhances development of parent–infant relationship. Biological Research For Nursing, 20(1), 54-62. https://doi.org/10.1177/1099800417735633.
  • World Health Organization (WHO) (2016). ‘’. Pregnancy, childbirth, postpartum and newborn care: a guide for essential practice –3rd ed.’’ https://www.who.int/publications/i/item/9789241549356. Erişim tarihi: 02 Ocak 2024.
  • World Health Organization (WHO) (2018). ‘’WHO recommendations: intrapartum care for a positive childbirth experience. Geneva: Licence: CC BY-NC-SA 3.0 IGO. https://apps.who.int/iris/bitstream/handle/10665/260178/9789241550215eng.pdf?sequence=1. Erişim tarihi: 02 Ocak 2024.
  • Yaman, S., Koç, EME, Hançerlioğulları, N., & Tekin, Ö. M. (2023). Doğum eyleminde anne ve fetal kanda melatonin ve beta-endorfin oluşumunun artması. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi , 20 (1), 1662-1667. https://doi.org/10.38136/jgon.1165727.
  • Yang, M. Y., LI, X. F., Zhang, H. W., Fan, T., XU, L. D., Qin, P. Y., & Yue, X. Q. (2018). Effect of epidural labor analgesia on the prolactin levels of parturient. Journal of Xinxiang Medical College, (12), 216-218. https://doi.org/10.22409/ijosd.wpr-699506.

Doğum Sürecinin Hormon Fizyoloji ile İlişkisi ve Ebe Önderliğinde Bakım

Yıl 2024, Cilt: 5 Sayı: 3, 286 - 302, 28.12.2024
https://doi.org/10.59244/ktokusbd.1564292

Öz

Doğumun süreci ve doğum sonu erken dönemde anne ve fetüsün/yenidoğanın iyilik hali, hormon fizyolojisiyle yakından ilişkilidir. Doğum sürecinde oksitosin, beta-endorfin, prolaktin ve stres hormonları etkili rol oynamaktadır. Buna ek olarak, melatoninin de doğumu etkileyen bir diğer hormon olduğu düşünülmektedir. Doğal doğum, hormonların birbirleriyle uyum içinde ve sinerjik salınımıyla mümkün olabilir. Bu nedenle, annenin stres ve korku yaşamasına neden olan faktörler hormon fizyolojisinin bozulmasına neden olarak annenin algıladığı ağrı seviyelerini artırabilir. Bu durum, doğumun ilerleyişini ve anne ile fetüs/yenidoğanın hem fiziksel hem de psikolojik sağlığını olumsuz etkileyebilir. Doğum süreci uygun bakım uygulamaları ve stratejileri ile yönetilirse, kadının stres hormonlarının salınımı azalır, beta-endorfin salınımı artar. Tolere edilen stres hormonları, doğumun doğal seyrinde ilerlemesini, oksitosin ve melatonin hormonlarının etkilerini ve birbirleriyle uyumunu olumlu etkiler. Bu uyum doğum ağrısıyla baş etmeye yardımcı olur. Böylece doğum süreci sekteye uğramaz ve doğumun ilerlemesi olumlu etkilenir. Bu pozitif döngüyü teşvik etmek, korumak ve desteklemek için ebe önderliğinde bakım uygulamaları oldukça önemlidir. Bu derlemede, doğum sürecinde etkili olan hormonlar, bu hormonların birbirleriyle ilişkisi ve ebe önderliğinde bakım uygulamaları için öneriler tartışılmıştır.

Kaynakça

  • Abd El-Aziz, S. N., Mansour, S., & Hassan, N. F. (2017). Factors associated with fear of childbirth: It’s effect on women’s preference for elective cesarean section. Journal of Nursing Education Practice, 7(1), 133-46. http://dx.doi.org/10.5430/jnep.v7n1p133
  • Aktas, S., & Pasinlioğlu, T. (2021). The effect of empathy training given to midwives on the empathic communication skills of midwives and the birth satisfaction of mothers giving birth with the help of these midwives: A quasi‐experimental study. Journal of Evaluation in Clinical Practice, 27(4), 858- 867. https://doi.org/10.1111/jep.13523
  • American College of Obstetricians and Gynecologists (ACOG). (2016). Prevention and management of obstetric lacerations at vaginal delivery. Obstetrics & Gynecology, 128(1), e1–e15. https://doi.org/10.1097/AOG.0000000000001523
  • American College of Obstetricians and Gynecologists (ACOG). (2019). Approaches to limitintervention in labor and birth. Obstetrics & Gynecology, 133(2), e164–e173. https://doi.org/10.1097/aog.0000000000003074
  • Aune, I., Torvik, H. M., Selboe, S. T., Skogås, A. K., Persen, J., & Dahlberg, U. (2015). Promoting a normal birth and a positive birth experience—Norwegian women׳ s perspectives. Midwifery, 31(7), 721-727. https://doi.org/10.1016/j.midw.2015.03.016
  • Ayres-de-Campos, D., Simon, A., Modi, N., Tudose, M., Saliba, E., Wielgos, M., ... & Jacobsson, B. (2024). European Association of Perinatal Medicine (EAPM) European Midwives Association (EMA) Joint position statement: Caesarean delivery rates at a country level should be in the 15-20% range. European Journal of Obstetrics & Gynecology and Reproductive Biology, 294, 76-78. https://doi.org/10.1016/j.ejogrb.2024.01.005.
  • Barus, E. B., & Massi, N. (2020). Cortisol levels and labor outcomes among women in the third trimester of pregnancy. Enfermería Clínica, 30 (2), 487-490. https://doi.org/10.1016/j.enfcli.2019.07.144
  • Benfield, R. D., Hortobagyi, T., Tanner, C. J., Swanson, M., Heitkem- per, M. M., & Newton, E. R. (2010). The effects of hydrotherapy on anxiety, pain, neuroendocrine responses, and contraction dynamics during labor. Biological Research for Nursing, 12(1), 28–36. http://dx.doi.org/10.1177/1099800410361535
  • Bleker, L. S., Roseboom, T. J., Vrijkotte, T. G., Reynolds, R. M., & de Rooij, S. R. (2017). Determinants of cortisol during pregnancy–The ABCD cohort. Psychoneuroendocrinology, 83 (1), 172-181. https://doi.org/10.1016/j.psyneuen.2017.05.026.
  • Buckley, S. J. (2015). Executive summary of hormonal physiology of childbearing: evidence and implications for women, babies, and maternity care. The Journal of Perinatal Education, 24(3), 145-153. https://doi.org/10.1891/1058-1243.24.3.145
  • Carlomagno, G., Minini, M., Tilotta, M., & Unfer, V. (2018). From implantation to birth: insight into molecular melatonin functions. International Journal of Molecular Sciences, 19(9), 2802. https://doi.org/10.3390/ijms19092802
  • de Brito Pitilin, E., Gasparin, V. A., Bagatini, M. D., & Lentsck, M. H. (2020). Determinants of the prolactin level in immediate postpartum women. Cogitare Enferm, 25, e71511. http://dx.doi.org/10.5380/ce.v25i0.71511.
  • Dick-Read, G. (2006). S. Childbirth Without Fear: The Principles and Practice of Natural Childbirth. London: Pollinger Limited. Sayfa 130-140.
  • Flores-Espinosa, P., Méndez, I., Irles, C., Olmos-Ortiz, A., Helguera-Repetto, C., Mancilla-Herrera, I. Ortuño-Sahagún, D., Goffin, V.,Zaga-Clavellina, V. (2023). Immunomodulatory role of decidual prolactin on the human fetal membranes and placenta. Frontiers in Immunology, 14, 1212736. https://doi.org/10.3389/fimmu.2023.1212736.
  • Hammond, A., Foureur, M., Homer, C. S., & Davis, D. (2013). Space, place and the midwife: Exploring the relationship between the birth environment, neurobiology and midwifery practice. Women and Birth, 26(4), 277-281. https://doi.org/10.1016/j.wombi.2013.09.001.
  • Hundley, V., Downe, S., & Buckley, S. J. (2020). The initiation of labour at term gestation: Physiology and practice implications. Best Practice & Research Clinical Obstetrics & Gynaecology, 67, 4-18. https://doi.org/10.1016/j.bpobgyn.2020.02.006.
  • Kenkel, W. 2021. Birth signalling hormones and the developmental consequences of caesarean delivery. Journal of Neuroendocrinology, 33(1), e12912. https://doi.org/10.1111/jne.12912
  • Goemaes, R., Beeckman, D., Verhaeghe, S., & Van Hecke, A. (2020). Sustaining the quality of midwifery practice in Belgium: Challenges and opportunities for advanced midwife practitioners. Midwifery, 89, 102792. https://doi.org/10.1016/j.midw.2020.102792.
  • Lawot, I., & Sharma, P. K. (2023). Effects of non-pharmacological methods on reduction labor pain among primiparous women: A Review. International Journal of Innovative Science and Research Technology, 8(7), 2456-2165. https://doi.org/10.38124/ijisrt/IJISRT23JUL11204.
  • Lorentzen, I. P., Andersen, C. S., Jensen, H. S., Fogsgaard, A., Foureur, M., Lauszus, F. F., & Nohr, E. A. (2021). Does giving birth in a “birth environment room” versus a standard birth room lower augmentation of labor?–Results from a randomized controlled trial. European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 10, 100125. https://doi.org/10.1016/j.eurox.2021.100125.
  • McCarthy, R., Jungheim, E. S., Fay, J. C., Bates, K., Herzog, E. D., & England, S. K. (2019). Riding the rhythm of melatonin through pregnancy to deliver on time. Frontiers in endocrinology, 10, 464826. https://doi.org/10.3389/fendo.2019.00616.
  • Mete, S. (2013). Stres, hormonlar ve doğum arasındaki ilişki. Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi, 6(2), 93-98.
  • Organisation for Economic Co-Operation and Development (OECD). 2020. ‘‘Caesarean sections (indicator)’’. https://doi: 10.1787/adc3c39f-en. Erişim tarihi; 17 Şubat 2024.
  • Rana, M., Jain, S., & Choubey, P. (2022). Prolactin and its significance in the placenta. Hormones, 21(2), 209-219. https://doi.org/10.1007/s42000-022-00373-y.
  • Reiter, R. J., Sharma, R., Chuffa, L. G. D., Zuccari, D. A., Amaral, F. G., & Cipolla-Neto, J. (2024). Melatonin-mediated actions and circadian functions that improve implantation, fetal health and pregnancy outcome. Reproductive Toxicology,124 (4), 108534. https://doi.org/10.1016/j.reprotox.2024.108534.
  • Rusnawati, M. S., Chalid, M. T., Saleh, A., Mappaware, N. A., Saidah Syamsuddin, J. J., Nur, A., & Halisah, A. T. (2024). Effectiveness Of The Application Of Respectful Midwifery Care On Prostaglandin (Pge2) Levels And Maternal Pain Perception Level In Normal Childbirth. Pakistan Journal of Life and Social Sciences, 22(2), 348-354. https://doi.org/10.57239/PJLSS-2024-22.2.0025.
  • Sakala, C., Romano, A. M., & Buckley, S. J. (2016). Hormonal physiology of childbearing, an essential framework for maternal–newborn nursing. Journal of Obstetric, Gynecologic & Neonatal Nursing, 45(2), 264-275. https://doi.org/10.1016/j.jogn.2015.12.006.
  • Sayiner, F. D., Öztürk, D. M., Ulupinar, E., Velipasaoglu, M., & Corumlu, E. P. (2021). Stress caused by environmental effects on the birth process and some of the labor hormones at rats: ideal birth environment and hormones. The journal of Maternal-Fetal & Neonatal Medicine, 34(16), 2600-2608. https://doi.org/10.1080/14767058.2019.1670162.
  • Stark, M. A., Remynse, M., & Zwelling, E. (2016). Importance of the birth environment to support physiologic birth. Journal of Obstetric, Gynecologic & Neonatal Nursing, 45(2), 285-294. https://doi.org/10.1016/j.jogn.2015.12.008
  • Stjernholm, Y. V., Nyberg, A., Cardell, M., & Höybye, C. (2016). Circulating maternal cortisol levels during vaginal delivery and elective cesarean section. Archives of Gynecology and Obstetrics, 294, 267 271. https://doi.org/10.1007/s00404-015-3981-x
  • Striebich, S., Mattern, E., and Ayerle, G. M. (2018). Support for pregnant women identified with fear of childbirth (DK)/tokophobia - A systematic review of approaches and interventions. Midwifery , 61 , 97-115. https://doi.org/10.1016/j.midw.2018.02.013.
  • Sulu, R., Akbas, M., & Cetiner, S. (2022). Effects of transcutaneous electrical nerve stimulation applied at different frequencies during labor on hormone levels, labor pain perception, and anxiety: A randomized placebo-controlled single-blind clinical trial. European Journal of Integrative Medicine, 52, 102124. https://doi.org/10.1016/j.eujim.2022.102124.
  • The United Nations (UN). (2017). ‘’The Sustainable development goals report 2017’’. The United Nations, New York, 20-24. https://unstats.un.org/sdgs/files/report/2017/thesustainabledevelopmentgoalsreport2017.pdf Son erişim tarihi: 03 Ocak 2024.
  • Türkiye Nüfus ve Sağlık Araştırması (TNSA). (2018). http://www.hips.hacettepe.edu.tr/tnsa2018/rapor/TNSA2018_ana_Rapor.pdf. Erişim tarihi; 17 Şubat 2024.
  • Uvnäs-Moberg, K. (2024). The physiology and pharmacology of oxytocin in labor and in the peripartum period. American Journal of Obstetrics and Gynecology, 230(3), S740-S758. https://doi.org/10.1016/j.ajog.2023.04.011
  • Verteramo, R., Pierdomenico, M., Greco, P., & Milano, C. (2022). The role of melatonin in pregnancy and the health benefits for the newborn. Biomedicines, 10(12), 3252. https://doi.org/10.3390/biomedicines10123252.
  • Vittner, D., McGrath, J., Robinson, J., Lawhon, G., Cusson, R., Eisenfeld, L., ... & Cong, X. (2018). Increase in oxytocin from skin-to-skin contact enhances development of parent–infant relationship. Biological Research For Nursing, 20(1), 54-62. https://doi.org/10.1177/1099800417735633.
  • World Health Organization (WHO) (2016). ‘’. Pregnancy, childbirth, postpartum and newborn care: a guide for essential practice –3rd ed.’’ https://www.who.int/publications/i/item/9789241549356. Erişim tarihi: 02 Ocak 2024.
  • World Health Organization (WHO) (2018). ‘’WHO recommendations: intrapartum care for a positive childbirth experience. Geneva: Licence: CC BY-NC-SA 3.0 IGO. https://apps.who.int/iris/bitstream/handle/10665/260178/9789241550215eng.pdf?sequence=1. Erişim tarihi: 02 Ocak 2024.
  • Yaman, S., Koç, EME, Hançerlioğulları, N., & Tekin, Ö. M. (2023). Doğum eyleminde anne ve fetal kanda melatonin ve beta-endorfin oluşumunun artması. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi , 20 (1), 1662-1667. https://doi.org/10.38136/jgon.1165727.
  • Yang, M. Y., LI, X. F., Zhang, H. W., Fan, T., XU, L. D., Qin, P. Y., & Yue, X. Q. (2018). Effect of epidural labor analgesia on the prolactin levels of parturient. Journal of Xinxiang Medical College, (12), 216-218. https://doi.org/10.22409/ijosd.wpr-699506.
Toplam 41 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Kadın Hastalıkları ve Doğum
Bölüm Derleme
Yazarlar

Rukiye Sülü Dursun 0000-0003-1093-4635

Aslıhan Turan 0000-0002-1635-719X

Ebru Gözüyeşil 0000-0002-9193-2182

Erken Görünüm Tarihi 26 Aralık 2024
Yayımlanma Tarihi 28 Aralık 2024
Gönderilme Tarihi 9 Ekim 2024
Kabul Tarihi 5 Kasım 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 5 Sayı: 3

Kaynak Göster

APA Sülü Dursun, R., Turan, A., & Gözüyeşil, E. (2024). Doğum Sürecinin Hormon Fizyoloji ile İlişkisi ve Ebe Önderliğinde Bakım. KTO Karatay Üniversitesi Sağlık Bilimleri Dergisi, 5(3), 286-302. https://doi.org/10.59244/ktokusbd.1564292