Treatment of Atopic Dermatıtıs in Children

Abstract

Abstract

Atopic dermatitis is a common chronic inflammatory skin disease associated with cutaneous hyperreactivity to various environmental triggers. The aim of the treatment should be focused on suppression of chronic inflammation and control of acute exacerbations. Basic therapy of atopic dermatitis should comprise optimal skin care with regular use of emollients, and avoidance from specific triggering factors. Topical treatment options like topical corticosteroids and calcineurin in hibitors are the milestones of the severe atopic dermatitis. The risk of adverse effects induced by topical corticosteroids could be reduced by proactive treatment modality. Topical calcineurin inhibitors allow a steroid-free anti-inflammatory topical treatment with a safe application on sensitive skin areas. Advanced treatment options should be administered as stepwise treatment, depending on the severity of the disease. In severe casesof atopic dermatitis, systemic oral steroids, immunosuppressant drugs, wet wrap, phototherapy and allergen immunotherapy can be administered. Systemic antibiotic treatment is indicated for widespread secondary bacterial skin infections. The management of atopic dermatitis should be individualized according to the severity of the disease and patients’ clinical conditions.

Keywords

• Child,atopic dermatitis,treatment

Çocuklarda Atopik Dermatit Tedavisi

Öz

Öz

Atopik dermatit çeşitli çevresel tetikleyicilerin ortaya çıkardığı aşırı cilt duyarlılığı ile ilişkili kronik enflamatuvar bir deri hastalığıdır. Tedavinin amacı kronik enflamasyonun baskılanması ve akut alevlenmelerin kontrol altına alınmasıdır. Atopik dermatitin temel tedavisi düzenli nemlendirici kullanımı ile uygun cilt bakımının sağlanması ve belirli tetikleyici etkenlerden uzak durulmasını içerir. Topikal kortikosteroidler ve kalsinörin inhibitörleri ağır atopik dermatit tedavisinin köşe taşını oluşturur. Topikal kortikosteroidler ile artan yan etki riski proaktif tedavi uygulaması ile azaltılabilir. Topikal kalsinörin inhibitörleri hassas cilt bölgelerine güvenle uygulanabilen steroid içermeyen topikal antienflamatuvar ilaçlardır. İleri tedavi seçenekleri, hastalığın ağırlığına bağlı olarak, basamak tedavisi şeklinde uygulanmalıdır. Ağıratopik dermatitli olgularda, sistemik tedavide oral steroidler, bağışıklık sistemini baskılayan ilaçlar, ıslak pansuman, fototerapi ve alerjen immunoterapisi uygulanabilir.Sistemik antibiyotik tedavisi yaygın ikincil bakteriyel cilt infeksiyonlarında kullanılmalıdır. Atopik dermatit tedavisi hastalığın ağırlığına ve hastanın klinik durumuna göre bireyselleştirilmelidir.

Anahtar Kelimeler

• Çocuk,atopik dermatit,tedavi

References

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