Çocuklarda Eozinofiliye Güncel Yaklaşım

Abstract

Abstract

The causes of peripheral blood eosinophilia range from benign eosinophilia to hypereosinophilic syndrome (HES) and malignancies. Clinical evaluation with a careful history and physical examination may help to determine the underlying cause. HES is a diagnosis of exclusion. Although drug allergy and parasitic diseases are common known causes of hypereosinophilia, it can also be seen in allergic diseases andvarious immunodeficiencies. Treatment is based on underlying disease. HES should be considered in patients with moderate to severe eosinophilia because delayed diagnosis and treatment may result in organ damage.

Keywords

• Hypereosinophilic Syndrome,Eosinophilia,Eosinophil,Eosinophilic Disorders

Çocuklarda Eozinofiliye Güncel Yaklaşım

Öz

Öz

Periferik kan eozinofili nedenleri benign eozinofiliden hipereozinofilik sendrom(HES) ve malignitelere kadar değişmektedir. Dikkatli bir öykü ve fizik muayene ile birlikte yapılan klinik değerlendirme, altta yatan nedeni belirlemeye yardımcı olabilir. HES bir dışlama tanısıdır. İlaç alerjisi ve paraziter hastalıklar hipereozinofilinin bilinen sık nedenleri olmasına rağmen, alerjik hastalıklar ve çeşitli immün yetmezliklerde de hipereozinofili görülebilmektedir. Tedavi altta yatan hastalığa göreyapılmaktadır. Orta-ağır eozinofilisi olan hastalarda HES mutlaka düşünülmelidir çünkü gecikmiş tanı ve tedavi organ hasarı ile sonuçlanabilir.

Anahtar Kelimeler

• Hipereozinofilik Sendrom,Eozinofil,EozinofilikHastalıklar,Eozinofili

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