Abstract
Abstract
Hashimoto encephalopathy (HE) is a rare/an uncommon disease/syndromewhich can include movement disorders, cognitive disabilities and psychiatricsymptoms. It is determined with elevated levels of thyroid antibodies in blood andcerebrospinal fluid and greatly responds to steroid treatment. Patients can be mildlyhypothyroidic or euthyroidic. It can be seen in all ages but especially in adolescen-ce. We represented 15-year-old female patient admitted to our hospital with acuteconvulsion and diagnosed as HE. Our aim is to increase awareness of this diseasein pediatric patients responding immediately after exact diagnosis.
Keywords
References
- Kaynaklar 1.Rallison ML, Dobyns BM, Keating FR, Rall JE, Tyler FH. Oc-currence and natural history of chronic lymphocytic thyroiditisin childhood. J Pediatr 1975; 86: 675–82. 2.Antonelli A, Ferrari SM, Corrado A, Di Domenicantonio A, Fal-lahi P. Autoimmune thyroid disorders. Autoimmun Rev 2015; 14:174–80. 3.Nandi-Munshi D, Taplin CE. Thyroid-related neurological disor-ders and complications in children. Pediatr Neurol 2015; 52:373–82. 4.Fatourechi V. Hashimoto’s encephalopathy: myth or reality? Anendocrinologist’s perspective. Best Pract Res Clin Endocrinol Me-tab 2005; 19: 53–66. 5.Mocellin R, Walterfang M, Velakoulis D. Hashimoto’s encepha-lopathy: epidemiology, pathogenesis and management. CNS Drugs2007; 21: 799–811. 6.Yoneda M, Fujii A, Ito A, Yokoyama H, Nakagawa H, KuriyamaM. High prevalence of serum autoantibodies against the aminoterminal of alpha-enolase in Hashimoto’s encephalopathy. J Neu-roimmunol 2007; 185: 195–200. 7.Ferracci F, Moretto G, Candeago RM, et al. Antithyroid antibo-dies in the CSF: their role in the pathogenesis of Hashimoto’s en-cephalopathy. Neurology 2003; 60: 712–14. 8.Castillo P, Woodruff B, Caselli R, et al. Steroid-responsive en-cephalopathy associated with autoimmune thyroiditis. ArchNeurol 2006; 63 (2): 197-202. 9.Montagna G, Imperiali M, Agazzi P, et al. Hashimoto's encep-halopathy: A rare proteiform disorder. Autoimmun Rev 2016; 15(5): 466-76. 10.Vasconcellos E, Pina-Garza JE, Fakhoury T, Fenichel GM. Pe-diatric manifestations of Hashimoto’s encephalopathy. PediatrNeurol 1999; 20: 394–98.
Abstract
Öz
Hashimoto ensefalopatisi (HE); epileptik nöbetler, hareket bozuklukları, kognitifbozukluklar ve psikiyatrik semptomları içerebilen, kan ve beyin-omurilik sıvısında tiroid antikorları yüksekliği ile karşımıza çıkan, steroid tedavisine çok iyi cevap veren nadir bir hastalıktır. Hastalar hafif düzeyde hipotiroidik veya ötiroidik olabilirler. Tümyaş gruplarını etkileyebileceği gibi çocukluk çağı içinde özellikle adolesan dönemde sık görülmektedir. Burada 15 yaşında akut konvülziyon ile başvuran HE tanısı almışbir kız hasta sunulmaktadır. Amacımız tanısı konulup tedaviye başlanıldığı zaman çokhızlı cevap alabildiğimiz bu hastalığın pediatrik çağdaki farkındalığını arttırmaktır.
Keywords
References
- Kaynaklar 1.Rallison ML, Dobyns BM, Keating FR, Rall JE, Tyler FH. Oc-currence and natural history of chronic lymphocytic thyroiditisin childhood. J Pediatr 1975; 86: 675–82. 2.Antonelli A, Ferrari SM, Corrado A, Di Domenicantonio A, Fal-lahi P. Autoimmune thyroid disorders. Autoimmun Rev 2015; 14:174–80. 3.Nandi-Munshi D, Taplin CE. Thyroid-related neurological disor-ders and complications in children. Pediatr Neurol 2015; 52:373–82. 4.Fatourechi V. Hashimoto’s encephalopathy: myth or reality? Anendocrinologist’s perspective. Best Pract Res Clin Endocrinol Me-tab 2005; 19: 53–66. 5.Mocellin R, Walterfang M, Velakoulis D. Hashimoto’s encepha-lopathy: epidemiology, pathogenesis and management. CNS Drugs2007; 21: 799–811. 6.Yoneda M, Fujii A, Ito A, Yokoyama H, Nakagawa H, KuriyamaM. High prevalence of serum autoantibodies against the aminoterminal of alpha-enolase in Hashimoto’s encephalopathy. J Neu-roimmunol 2007; 185: 195–200. 7.Ferracci F, Moretto G, Candeago RM, et al. Antithyroid antibo-dies in the CSF: their role in the pathogenesis of Hashimoto’s en-cephalopathy. Neurology 2003; 60: 712–14. 8.Castillo P, Woodruff B, Caselli R, et al. Steroid-responsive en-cephalopathy associated with autoimmune thyroiditis. ArchNeurol 2006; 63 (2): 197-202. 9.Montagna G, Imperiali M, Agazzi P, et al. Hashimoto's encep-halopathy: A rare proteiform disorder. Autoimmun Rev 2016; 15(5): 466-76. 10.Vasconcellos E, Pina-Garza JE, Fakhoury T, Fenichel GM. Pe-diatric manifestations of Hashimoto’s encephalopathy. PediatrNeurol 1999; 20: 394–98.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | makale |
| Authors | |
| Publication Date | May 5, 2016 |
| Published in Issue | Year 2016 Volume: 8 Issue: 3 |
