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Respiratory Problems and Management in Prematurity

Year 2017, Volume: 9 Issue: 4, 17 - 32, 20.07.2017

Abstract

Abstract

Respiratory distressis the most frequent cause of admission to the neonatal intensive care units both in term and preterm infants.Respiratory distress related to prematurity include delayed neonatal transition to air breathing, respiratory distress resulting from delayed fetal lung fluid clearance, surfactant deficiency, deficiency ofantioxidant systems and birth at an early stage of lung development. Neonatal respiratory distress may be transient; however, persistent distress requires a rational di-agnostic and therapeutic approach to decrease mortality and minimize morbidity.

References

  • Kaynaklar 1.Arun K. Pramanik, Nandeesh Rangaswamy, Thomas Gates.Neonatal Respiratory Distress: A Practical Approach to ItsDiagnosis and Management. Pediatr Clin N Am 2015; 62:453–469. 2.Colin A, McEvoy C, Castile RG. Respiratory morbidity andlung function in preterm infants of 32 to 36 weeks’ gestatio-nal age. Pediatrics 2010;126(1):115–28. 3.Bland RD. Lung fluid balance during development. Neorevi-ews 2005;6(6): e255–65. 4.Edwards MO, Kotecha SJ, Kotecha S. Respiratory distress ofthe term newborn infant. Paediatr Respir Rev 2013;14:29–37. 5.Fraser D. Respiratory distress. In: Verklan MT, Walden M,editors. Core Curriculum for neonatal intensive care nursing,5th edtion. Saunders; 2014. p. 447-477. 6.Martin RJ, Fanaroff AA, Walsh MC. The respiratory systemin Fanaroff and Martin’s neonatal-perinatal medicine. In: Di-seases of the fetus and infants. 10th edition. Elsevier, Mosby;2014. p. 1075–206. 7.Eichenwald EC, Committee on Fetus and Newborn, Ameri-can Academy of Pediatrics. Apnea of Prematurity. Pediatrics2016; 137. 8.Perlman JM, Wyllie J, Kattwinkel J, et al. Part 7: neonatalresuscitation: 2015 InternationalConsensus on Cardiopulmo-nary Resuscitation and Emergency Cardiovascular Care Sci-ence With Treatment Recommendations. Circulation.2015;132(suppl 1): S204–S241. 9.Stanley CA, Rozance PJ, Thornton PS, De Leon DD, HarrisD, Haymond MW, et al. Re-evaluating “transitional neona-tal hypoglycemia”: mechanism and implications for manage-ment. J Pediatr 2015;166:1520-5. 10.Sconyers SM, Ogden BE, Goldberg HS.The effect of body po-sition on the respiratory rate of infants with tachypnea. J Pe-rinatol. 1987 Spring;7(2):118-21. 11.Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plav-ka R, et al. European consensus guidelines on the managementof respiratory distress syndrome - 2016 update. Neonatology2017;111:107–125. 12.Özkan H, Erdeve Ö, Karadağ A. Türk Neonatoloji Derneği Res-piratuvar Distres Sendromu Rehberi, 2014. 13.Richard A. Polin, Waldemar A. Carlo, Commıttee on Fetus andNewborn. Surfactant Replacement Therapy for Preterm andTerm Neonates With Respiratory Distress. Pediatrics.Fromthe American Academy of PediatricsClinical Report. 14.Roberts D, Dalziel S: Antenatal corticosteroids for accelera-ting fetal lung maturation for women at risk of preterm birth.Cochrane Database Syst Rev 2006;3:CD004454. 15.Gyamfi-Bannerman C, Thom EA, Blackwell SC, Tita AT, ReddyUM, Saade GR, et al: Antenatal betamethasone for women atrisk for late preterm delivery. N Engl J Med 2016;374:1311–1320. 16.Sotiriadis A, Makrydimas G, Papatheodorou S, Ioannidis JP:Corticosteroids for preventing neonatal respiratory morbidityafter elective caesarean section at term. Cochrane Databa-se Syst Rev 2009;4:CD006614. 17.Bhatt S, Alison BJ, Wallace EM, Crossley KJ, Gill AW, Kluc-kow M, te Pas AB, et al: Delaying cord clamping until ven-tilation onset improves cardiovascular function at birth in pre-term lambs. J Physiol 2013;591:2113–2126. 18.Wyllie J, Bruinenberg J, Roehr CC, Rüdiger M, TrevisanutoD, Urlesberger B: European Resuscitation Council guideli-nes for resuscitation 2015. Section 7: resuscitation and sup-port of transition of babies at birth. Resuscitation2015;95:249–263. 19.Phillipos E, Solevåg AL, Pichler G, Aziz K, van Os S, O’Re-illy M, et al: Heart rate assessment immediately after birth.Neonatology 2016;109:130–138. 20.Singh N, Halliday HL, Stevens TP, Suresh G, Soll R, Rojas-Reyes MX: Comparison of animal-derived surfactants for theprevention and treatment of respiratory distress syndrome inpreterm infants. Cochrane Database Syst Rev2015;12:CD010249. 21.Rojas-Reyes MX, Morley CJ, Soll RF. Prophylactic versus se-lective use of surfactant in preventing morbidity and morta-lity in preterm infants. Cochrane Database Syst Rev. 2012:(3):CD000510. 22.Soll R, Ozek E: Multiple versus single doses of exogenous sur-factant for the prevention or treatment of neonatal respiratorydistress syndrome. Cochrane Database Syst Rev 2009;1:CD000141. 23.Stevens TP, Harrington EW, Blennow M, Soll RF: Early sur-factant administration with brief ventilation vs selective sur-factant and continued mechanical ventilation for preterm in-fants with or at risk for respiratory distress syndrome. Coch-rane Database Syst Rev 2007; 4:CD003063. 24.Kanmaz HG, Erdeve O, Canpolat FE, Mutlu B, Dilmen U: Sur-factant administration via thin catheter during spontaneousbreathing: randomized controlled trial. Pediatrics 2013;131:e502–e509. 25.More K, Sakhuja P, Shah PS: Minimally invasive surfactantadministration in preterm infants: a meta-narrative review.JAMA Pediatr 2014;168:901–908. 26.Stenson BJ: Oxygen saturation targets for extremely preterminfants after the NeOProM trials. Neonatology2016;109:352–358. 27.Bell EF, Acarregui MJ: Restricted versus liberal water inta-ke for preventing morbidity and mortality in preterm infants.Cochrane Database Syst Rev 2014;12:CD000503. 28.Morgan J, Young L, McGuire W: Delayed introduction of prog-ressive enteral feeds to prevent necrotising enterocolitis in verylow birth weight infants. Cochrane Database Syst Rev2014;12:CD001970. 29.Yurdakök M. Transient tachypnea of the newborn: what is new?J Matern Fetal Neonatal Med 2010;23(Suppl 3):24–6. 30.Kassab M, Khriesat WM, Anabrees J: Diuretics for transienttachypnoea of the newborn. Cochrane Database Syst Rev. 2015Nov 21;(11):CD003064. 31.Moresco L, Bruschettini M, Cohen A, Gaiero A, Calevo MG:Salbutamol for transient tachypnea of the newborn.Cochra-ne Database Syst Rev. 2016 May 23;(5):CD011878. 32.Moresco L, Calevo MG, Baldi F, Cohen A, Bruschettini M.Epinephrine for transient tachypnea of the newborn.Cochra-ne Database Syst Rev. 2016 May 23;(5):CD011877. 33.Satar M, Arısoy AE. Türk Neonatoloji Derneği Yenidoğan En-feksiyonları Tedavi ve İzlem Rehberi2014. 34.Narlı N. Hava kaçakları. Turkiye Klinikleri J Pediatr Sci 2013;9(1):44-51. 35.Aly H, Massaro A, Acun C, Ozen M: Pneumothorax in the new-born: clinical presentation, risk factors and outcomes. J Ma-tern Fetal Neonatal Med 2014;27:402-406. 36.Bhatia R, Davis PG, Doyle LW, et al. Identification of pneu-mothorax in very preterm infants. J Pediatr 2011; 159:115. 37.Stanton M, Davenport M. Management of congenital lung le-sions. Early Hum Dev 2006;82(5):289–95.

Prematürede Solunum Problemleri ve Yönetimi

Year 2017, Volume: 9 Issue: 4, 17 - 32, 20.07.2017

Abstract

Öz

Hem term hem de preterm bebekler için yenidoğan yoğun bakım ünitelerine yatışın en sık sebebi solunum sıkıntısıdır. Preterm doğumlar ciddi solunumsal morbidite ve mortalite ile sonuçlanabilmektedir. Prematüre bebeklerde görülen solunum sıkıntısı çoğunlukla fetal ortamdan ekstrauterin çevreye geçiş süresinin uzamasından,fetal akciğer sıvısının klirensindeki gecikmeden, surfaktan eksikliğinden,  antioksidansistemlerin yetersizliğinden ve doğumun akciğer gelişiminin erken bir evresinde olmasından kaynaklanır. Preterm bebeklerde solunum sıkıntısı geçici olabilmesine rağmen devam eden solunum sıkıntısında mortaliteyi azaltmak ve morbiditeyi en aza indirmek için rasyonel bir tanı ve tedavi yaklaşımı gerektirir.

References

  • Kaynaklar 1.Arun K. Pramanik, Nandeesh Rangaswamy, Thomas Gates.Neonatal Respiratory Distress: A Practical Approach to ItsDiagnosis and Management. Pediatr Clin N Am 2015; 62:453–469. 2.Colin A, McEvoy C, Castile RG. Respiratory morbidity andlung function in preterm infants of 32 to 36 weeks’ gestatio-nal age. Pediatrics 2010;126(1):115–28. 3.Bland RD. Lung fluid balance during development. Neorevi-ews 2005;6(6): e255–65. 4.Edwards MO, Kotecha SJ, Kotecha S. Respiratory distress ofthe term newborn infant. Paediatr Respir Rev 2013;14:29–37. 5.Fraser D. Respiratory distress. In: Verklan MT, Walden M,editors. Core Curriculum for neonatal intensive care nursing,5th edtion. Saunders; 2014. p. 447-477. 6.Martin RJ, Fanaroff AA, Walsh MC. The respiratory systemin Fanaroff and Martin’s neonatal-perinatal medicine. In: Di-seases of the fetus and infants. 10th edition. Elsevier, Mosby;2014. p. 1075–206. 7.Eichenwald EC, Committee on Fetus and Newborn, Ameri-can Academy of Pediatrics. Apnea of Prematurity. Pediatrics2016; 137. 8.Perlman JM, Wyllie J, Kattwinkel J, et al. Part 7: neonatalresuscitation: 2015 InternationalConsensus on Cardiopulmo-nary Resuscitation and Emergency Cardiovascular Care Sci-ence With Treatment Recommendations. Circulation.2015;132(suppl 1): S204–S241. 9.Stanley CA, Rozance PJ, Thornton PS, De Leon DD, HarrisD, Haymond MW, et al. Re-evaluating “transitional neona-tal hypoglycemia”: mechanism and implications for manage-ment. J Pediatr 2015;166:1520-5. 10.Sconyers SM, Ogden BE, Goldberg HS.The effect of body po-sition on the respiratory rate of infants with tachypnea. J Pe-rinatol. 1987 Spring;7(2):118-21. 11.Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plav-ka R, et al. European consensus guidelines on the managementof respiratory distress syndrome - 2016 update. Neonatology2017;111:107–125. 12.Özkan H, Erdeve Ö, Karadağ A. Türk Neonatoloji Derneği Res-piratuvar Distres Sendromu Rehberi, 2014. 13.Richard A. Polin, Waldemar A. Carlo, Commıttee on Fetus andNewborn. Surfactant Replacement Therapy for Preterm andTerm Neonates With Respiratory Distress. Pediatrics.Fromthe American Academy of PediatricsClinical Report. 14.Roberts D, Dalziel S: Antenatal corticosteroids for accelera-ting fetal lung maturation for women at risk of preterm birth.Cochrane Database Syst Rev 2006;3:CD004454. 15.Gyamfi-Bannerman C, Thom EA, Blackwell SC, Tita AT, ReddyUM, Saade GR, et al: Antenatal betamethasone for women atrisk for late preterm delivery. N Engl J Med 2016;374:1311–1320. 16.Sotiriadis A, Makrydimas G, Papatheodorou S, Ioannidis JP:Corticosteroids for preventing neonatal respiratory morbidityafter elective caesarean section at term. Cochrane Databa-se Syst Rev 2009;4:CD006614. 17.Bhatt S, Alison BJ, Wallace EM, Crossley KJ, Gill AW, Kluc-kow M, te Pas AB, et al: Delaying cord clamping until ven-tilation onset improves cardiovascular function at birth in pre-term lambs. J Physiol 2013;591:2113–2126. 18.Wyllie J, Bruinenberg J, Roehr CC, Rüdiger M, TrevisanutoD, Urlesberger B: European Resuscitation Council guideli-nes for resuscitation 2015. Section 7: resuscitation and sup-port of transition of babies at birth. Resuscitation2015;95:249–263. 19.Phillipos E, Solevåg AL, Pichler G, Aziz K, van Os S, O’Re-illy M, et al: Heart rate assessment immediately after birth.Neonatology 2016;109:130–138. 20.Singh N, Halliday HL, Stevens TP, Suresh G, Soll R, Rojas-Reyes MX: Comparison of animal-derived surfactants for theprevention and treatment of respiratory distress syndrome inpreterm infants. Cochrane Database Syst Rev2015;12:CD010249. 21.Rojas-Reyes MX, Morley CJ, Soll RF. Prophylactic versus se-lective use of surfactant in preventing morbidity and morta-lity in preterm infants. Cochrane Database Syst Rev. 2012:(3):CD000510. 22.Soll R, Ozek E: Multiple versus single doses of exogenous sur-factant for the prevention or treatment of neonatal respiratorydistress syndrome. Cochrane Database Syst Rev 2009;1:CD000141. 23.Stevens TP, Harrington EW, Blennow M, Soll RF: Early sur-factant administration with brief ventilation vs selective sur-factant and continued mechanical ventilation for preterm in-fants with or at risk for respiratory distress syndrome. Coch-rane Database Syst Rev 2007; 4:CD003063. 24.Kanmaz HG, Erdeve O, Canpolat FE, Mutlu B, Dilmen U: Sur-factant administration via thin catheter during spontaneousbreathing: randomized controlled trial. Pediatrics 2013;131:e502–e509. 25.More K, Sakhuja P, Shah PS: Minimally invasive surfactantadministration in preterm infants: a meta-narrative review.JAMA Pediatr 2014;168:901–908. 26.Stenson BJ: Oxygen saturation targets for extremely preterminfants after the NeOProM trials. Neonatology2016;109:352–358. 27.Bell EF, Acarregui MJ: Restricted versus liberal water inta-ke for preventing morbidity and mortality in preterm infants.Cochrane Database Syst Rev 2014;12:CD000503. 28.Morgan J, Young L, McGuire W: Delayed introduction of prog-ressive enteral feeds to prevent necrotising enterocolitis in verylow birth weight infants. Cochrane Database Syst Rev2014;12:CD001970. 29.Yurdakök M. Transient tachypnea of the newborn: what is new?J Matern Fetal Neonatal Med 2010;23(Suppl 3):24–6. 30.Kassab M, Khriesat WM, Anabrees J: Diuretics for transienttachypnoea of the newborn. Cochrane Database Syst Rev. 2015Nov 21;(11):CD003064. 31.Moresco L, Bruschettini M, Cohen A, Gaiero A, Calevo MG:Salbutamol for transient tachypnea of the newborn.Cochra-ne Database Syst Rev. 2016 May 23;(5):CD011878. 32.Moresco L, Calevo MG, Baldi F, Cohen A, Bruschettini M.Epinephrine for transient tachypnea of the newborn.Cochra-ne Database Syst Rev. 2016 May 23;(5):CD011877. 33.Satar M, Arısoy AE. Türk Neonatoloji Derneği Yenidoğan En-feksiyonları Tedavi ve İzlem Rehberi2014. 34.Narlı N. Hava kaçakları. Turkiye Klinikleri J Pediatr Sci 2013;9(1):44-51. 35.Aly H, Massaro A, Acun C, Ozen M: Pneumothorax in the new-born: clinical presentation, risk factors and outcomes. J Ma-tern Fetal Neonatal Med 2014;27:402-406. 36.Bhatia R, Davis PG, Doyle LW, et al. Identification of pneu-mothorax in very preterm infants. J Pediatr 2011; 159:115. 37.Stanton M, Davenport M. Management of congenital lung le-sions. Early Hum Dev 2006;82(5):289–95.
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Details

Primary Language Turkish
Journal Section makale
Authors

Prof. Dr. Nuray Duman

Publication Date July 20, 2017
Published in Issue Year 2017 Volume: 9 Issue: 4

Cite

APA Duman, P. D. N. (2017). Prematürede Solunum Problemleri ve Yönetimi. Klinik Tıp Pediatri Dergisi, 9(4), 17-32.
AMA Duman PDN. Prematürede Solunum Problemleri ve Yönetimi. Pediatri. July 2017;9(4):17-32.
Chicago Duman, Prof. Dr. Nuray. “Prematürede Solunum Problemleri Ve Yönetimi”. Klinik Tıp Pediatri Dergisi 9, no. 4 (July 2017): 17-32.
EndNote Duman PDN (July 1, 2017) Prematürede Solunum Problemleri ve Yönetimi. Klinik Tıp Pediatri Dergisi 9 4 17–32.
IEEE P. D. N. Duman, “Prematürede Solunum Problemleri ve Yönetimi”, Pediatri, vol. 9, no. 4, pp. 17–32, 2017.
ISNAD Duman, Prof. Dr. Nuray. “Prematürede Solunum Problemleri Ve Yönetimi”. Klinik Tıp Pediatri Dergisi 9/4 (July 2017), 17-32.
JAMA Duman PDN. Prematürede Solunum Problemleri ve Yönetimi. Pediatri. 2017;9:17–32.
MLA Duman, Prof. Dr. Nuray. “Prematürede Solunum Problemleri Ve Yönetimi”. Klinik Tıp Pediatri Dergisi, vol. 9, no. 4, 2017, pp. 17-32.
Vancouver Duman PDN. Prematürede Solunum Problemleri ve Yönetimi. Pediatri. 2017;9(4):17-32.