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Neonatal Sepsise Güncel Bakış

Year 2020, Volume: 12 Issue: 3, 140 - 146, 01.06.2020

Mustafa Törehan Aslan

Abstract

Neonatal sepsis, büyük çabalara rağmen az ilerleme kaydedilen önemli bir küresel
sorun olmaya devam etmektedir. Şu anda neonatal sepsisin tanımlanması, tanısı
ve tedavisi konusunda kabul edilmiş bir uluslararası görüş birliği yoktur. Neonatal
sepsisin tanımı, insidansı, etiyolojisi, patofizyolojisi, risk faktörleri, klinik bulgu
ve semptomları, tanı, tedavi ve prognozu ile ilgili gelişmeler derlenmiştir.

Keywords

yenidoğan sepsis erken başlangıçlı neonatal sepsis geç başlangıçlı neonatal sepsis

References

  • 1. NICE guidance. Neonatal infection (early onset): antibiotics for prevention and treatment. Available: https://www.nice. org.uk/guidance/cg149 (erişim tarihi: 22.04. 2020)
  • 2. Stoll BJ, Hansen NI, Sanchez PJ, et al. Early onset neonatal sepsis: the burden of group B Streptococcal and E. coli disease continues. Pediatrics 2011; 127 (5): 817-826.
  • 3. Dong Y, Speer CP. Late-onset neonatal sepsis: recent developments. Arch Dis Child Fetal Neonatal Ed 2015; 100 (3): F257-263.
  • 4. Türk Neonatoloji Derneği, Yenidoğan Enfeksiyonları Tanı ve Tedavi Rehberi, 2018 Güncellemesi.
  • 5. Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis. Management of neonates born at ≥35 0/7 weeks’ gestation with suspected or proven early-onset bacterial sepsis. Pediatrics 2018; 142 (6): e20182894, doi. org/ 10. 1542/ peds. 2018- 2894.
  • 6. https://www.msdmanuals.com/professional/pediatrics/infections- in-neonates/neonatal-sepsis# (erişim tarihi: 25.04.2020)
  • 7. Stoll BJ, Schuchat A. Maternal carriage of group B streptococci in developing countries. Pediatr Infect Dis J 1998; 17 (6): 499-503.
  • 8. Kireçci E, Özer A, Arıkan DC, Gül M. Group B streptococcal vaginal colonization in the third trimester of pregnancy. Gynecology Obstetrics & Reproductive Medicine 2010; 16: 144-148.
  • 9. Gül H, Dede M, Avcı İ, Eyigün C, Pahsa A. Üçüncü trimestr hamilelerde vaginal grup B streptokok kolonizasyonu. Klimik Derg 2005; 18 (1): 27-29.
  • 10. Karadeniz M, Ekmekçioğlu YA, Öztürk R, Tokuç G, Özgüner A. Gebelerde ve yenidoğan bebeklerde grup B streptokok (St. agalactiae) sıklığının araştırılması. J Kartal TR 1998; (9) 1: 683-686.
  • 11. Pontrelli G, De Crescenzo F, Buzzetti R, et al: Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and
  • children with systemic inflammatory syndrome: A metaanalysis. BMC Infect Dis 2017; 17 (1): 302. doi: 10.1186/s12879-017-2396-7.
  • 12. Benitz WE. Adjunct laboratory tests in the diagnosis of early-onset neonatal sepsis. Clin Perinatol 2010; 37 (2): 421–438.
  • 13. Lynema S, Marmer D, Hall ES, Meinzen-Derr J, Kingma PS. Neutrophil CD64 as a diagnostic marker of sepsis: impact on neonatal care. Am J Perinatol 2015; 32 (4): 331–336.
  • 14. Su H, Chang SS, Han CM, et al. Inflammatory markers in cord blood or maternal serum for early detection of neonatal sepsis-
  • a systemic review and meta-analysis. J Perinatol 2014; 34 (4): 268–274.
  • 15. Chiesa C, Panero A, Rossi N, et al. Reliability of procalcitonin concentrations for the diagnosis of sepsis in critically ill neonates. Clin Infect Dis 1998; 26 (3): 664–672.
  • 16. Çetin BS, Celebi S, Özkan H, et al. Stenotrophomonas maltophilia outbreak in neonatal intensive care unit and outbreak
  • management. J Pediatr Inf 2015; 9: 147-152. doi: 10.5152/ced.2015.2180.
  • 17. Puopolo KM, Benitz WE, Zaoutis TE, AAP Committee on fetus and newborn, AAP Committee on Infectious Diseases. Management of neonates born at ≤34 6/7 weeks’ gestation with
  • suspected or proven early-onset bacterial sepsis. Pediatrics 2018; 142 (6): e20182896. doi: https:// doi. org/ 10. 1542/ peds. 2018-2896.
  • 18. Puopolo KM, Benitz WE, Zaoutis TE, AAP Committee on fetus and newborn, AAP Committee on Infectious Diseases. Management of neonates born at ≥35 0/7 weeks’ gestation with
  • suspected or proven early-onset bacterial sepsis. Pediatrics 2018; 142 (6): e20182894. doi: https:// doi. org/ 10. 1542/ peds. 2018-2894.
  • 19. Tzialla C, Borghesi A, Pozzi M, Stronati M. Neonatal infections due to multi-resistant strains: Epidemiology, current treatment,
  • emerging therapeutic approaches and prevention. Clin Chim Acta 2015; 451 (Pt A): 71-77.
  • 20. Bendel CM. Candidiasis. In: Wilson C, Nizet V, Maldonado Y, Remington J, Klein J eds. Infectious Disease of the Newborn and Fetus, 9 ed., Philadelphia: Elsevier Saunders, 2015: 1058-1079.
  • 21. Cleminson J, Austin N, McGuire W. Prophylactic systemic antifungal agents to prevent mortality and morbidity in very low
  • birth weight infants. Cochrane Database Syst Rev 2015 (10): CD003850.

Year 2020, Volume: 12 Issue: 3, 140 - 146, 01.06.2020

Mustafa Törehan Aslan

Abstract

References

  • 1. NICE guidance. Neonatal infection (early onset): antibiotics for prevention and treatment. Available: https://www.nice. org.uk/guidance/cg149 (erişim tarihi: 22.04. 2020)
  • 2. Stoll BJ, Hansen NI, Sanchez PJ, et al. Early onset neonatal sepsis: the burden of group B Streptococcal and E. coli disease continues. Pediatrics 2011; 127 (5): 817-826.
  • 3. Dong Y, Speer CP. Late-onset neonatal sepsis: recent developments. Arch Dis Child Fetal Neonatal Ed 2015; 100 (3): F257-263.
  • 4. Türk Neonatoloji Derneği, Yenidoğan Enfeksiyonları Tanı ve Tedavi Rehberi, 2018 Güncellemesi.
  • 5. Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis. Management of neonates born at ≥35 0/7 weeks’ gestation with suspected or proven early-onset bacterial sepsis. Pediatrics 2018; 142 (6): e20182894, doi. org/ 10. 1542/ peds. 2018- 2894.
  • 6. https://www.msdmanuals.com/professional/pediatrics/infections- in-neonates/neonatal-sepsis# (erişim tarihi: 25.04.2020)
  • 7. Stoll BJ, Schuchat A. Maternal carriage of group B streptococci in developing countries. Pediatr Infect Dis J 1998; 17 (6): 499-503.
  • 8. Kireçci E, Özer A, Arıkan DC, Gül M. Group B streptococcal vaginal colonization in the third trimester of pregnancy. Gynecology Obstetrics & Reproductive Medicine 2010; 16: 144-148.
  • 9. Gül H, Dede M, Avcı İ, Eyigün C, Pahsa A. Üçüncü trimestr hamilelerde vaginal grup B streptokok kolonizasyonu. Klimik Derg 2005; 18 (1): 27-29.
  • 10. Karadeniz M, Ekmekçioğlu YA, Öztürk R, Tokuç G, Özgüner A. Gebelerde ve yenidoğan bebeklerde grup B streptokok (St. agalactiae) sıklığının araştırılması. J Kartal TR 1998; (9) 1: 683-686.
  • 11. Pontrelli G, De Crescenzo F, Buzzetti R, et al: Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and
  • children with systemic inflammatory syndrome: A metaanalysis. BMC Infect Dis 2017; 17 (1): 302. doi: 10.1186/s12879-017-2396-7.
  • 12. Benitz WE. Adjunct laboratory tests in the diagnosis of early-onset neonatal sepsis. Clin Perinatol 2010; 37 (2): 421–438.
  • 13. Lynema S, Marmer D, Hall ES, Meinzen-Derr J, Kingma PS. Neutrophil CD64 as a diagnostic marker of sepsis: impact on neonatal care. Am J Perinatol 2015; 32 (4): 331–336.
  • 14. Su H, Chang SS, Han CM, et al. Inflammatory markers in cord blood or maternal serum for early detection of neonatal sepsis-
  • a systemic review and meta-analysis. J Perinatol 2014; 34 (4): 268–274.
  • 15. Chiesa C, Panero A, Rossi N, et al. Reliability of procalcitonin concentrations for the diagnosis of sepsis in critically ill neonates. Clin Infect Dis 1998; 26 (3): 664–672.
  • 16. Çetin BS, Celebi S, Özkan H, et al. Stenotrophomonas maltophilia outbreak in neonatal intensive care unit and outbreak
  • management. J Pediatr Inf 2015; 9: 147-152. doi: 10.5152/ced.2015.2180.
  • 17. Puopolo KM, Benitz WE, Zaoutis TE, AAP Committee on fetus and newborn, AAP Committee on Infectious Diseases. Management of neonates born at ≤34 6/7 weeks’ gestation with
  • suspected or proven early-onset bacterial sepsis. Pediatrics 2018; 142 (6): e20182896. doi: https:// doi. org/ 10. 1542/ peds. 2018-2896.
  • 18. Puopolo KM, Benitz WE, Zaoutis TE, AAP Committee on fetus and newborn, AAP Committee on Infectious Diseases. Management of neonates born at ≥35 0/7 weeks’ gestation with
  • suspected or proven early-onset bacterial sepsis. Pediatrics 2018; 142 (6): e20182894. doi: https:// doi. org/ 10. 1542/ peds. 2018-2894.
  • 19. Tzialla C, Borghesi A, Pozzi M, Stronati M. Neonatal infections due to multi-resistant strains: Epidemiology, current treatment,
  • emerging therapeutic approaches and prevention. Clin Chim Acta 2015; 451 (Pt A): 71-77.
  • 20. Bendel CM. Candidiasis. In: Wilson C, Nizet V, Maldonado Y, Remington J, Klein J eds. Infectious Disease of the Newborn and Fetus, 9 ed., Philadelphia: Elsevier Saunders, 2015: 1058-1079.
  • 21. Cleminson J, Austin N, McGuire W. Prophylactic systemic antifungal agents to prevent mortality and morbidity in very low
  • birth weight infants. Cochrane Database Syst Rev 2015 (10): CD003850.
There are 28 citations in total.

Details

Primary Language Turkish
Subjects ​Internal Diseases
Journal Section makale
Authors

Mustafa Törehan Aslan This is me

Publication Date June 1, 2020
Published in Issue Year 2020 Volume: 12 Issue: 3

Cite

APA Aslan, M. T. (2020). Neonatal Sepsise Güncel Bakış. Klinik Tıp Pediatri Dergisi, 12(3), 140-146.
AMA Aslan MT. Neonatal Sepsise Güncel Bakış. Pediatri. June 2020;12(3):140-146.
Chicago Aslan, Mustafa Törehan. “Neonatal Sepsise Güncel Bakış”. Klinik Tıp Pediatri Dergisi 12, no. 3 (June 2020): 140-46.
EndNote Aslan MT (June 1, 2020) Neonatal Sepsise Güncel Bakış. Klinik Tıp Pediatri Dergisi 12 3 140–146.
IEEE M. T. Aslan, “Neonatal Sepsise Güncel Bakış”, Pediatri, vol. 12, no. 3, pp. 140–146, 2020.
ISNAD Aslan, Mustafa Törehan. “Neonatal Sepsise Güncel Bakış”. Klinik Tıp Pediatri Dergisi 12/3 (June 2020), 140-146.
JAMA Aslan MT. Neonatal Sepsise Güncel Bakış. Pediatri. 2020;12:140–146.
MLA Aslan, Mustafa Törehan. “Neonatal Sepsise Güncel Bakış”. Klinik Tıp Pediatri Dergisi, vol. 12, no. 3, 2020, pp. 140-6.
Vancouver Aslan MT. Neonatal Sepsise Güncel Bakış. Pediatri. 2020;12(3):140-6.
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