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Alkylphenols in the Environment and Their Adverse Effects on Living Organisms
Abstract
Alkilfenol bileşikleri (AFEO) iyonic olmayan yüzey aktif maddesi olarak deterjanlarda, ot ve böcek ilaçlarında, kozmeiklerde, plastik eşyalarda emülsifikatörlerde, boyalarda ve hatta uçak yakıtlarında çok yaygın kullanılan östrojenik endokrin sistem bozuculardır. Alkilfenol adı verilen AFEO bilişiklerinin türevlerinin hem suda hem de karada yaşayan canlılara zararlı etkileri olduğu rapor edilmiştir. Ayrıca, bunların hem östrojenik, hem toksik hem de karinojenik etkileri olduğu ortaya konmuştur. Bu nedenle, AFEO bileşikleriri ve türevlerinin doğadaki varoluşları, yapıları, biyolojik bozunumları, biyolojik birikimleri, metbolize edilme yolları ve insan dahil bütün canlı organizmalara olan zararlı etkileri karmaşık literatür taranarak potnsiyel zararlı etkileri anlaşılmaya çalışılmıştır. Bu literatür taraması ile doğada bulunan AFEO bileşikleri ve türevlerinin miktarlarının öldürücü dozlarda olmadığı anlaşılmıştır. Fakat, bu bileşiklerin ve türevlerinin öldürücü olmayan dozlarının da insan dahil bütün canlı organizmalarda hem östrojenik hem de karsinojenik etkilerinin olduğu ortaya konmuştur
Keywords
References
- Nimrod AC, Benson WH (1996) Environmental estrogenic effects of akylphenol etoxylates. Crit Rev Toxicol, 26(3): 335-364.
- Sharpe RM (2001) Hormones and testis development and the possible adverse effects of environmental chemicals. Toxicol Lett, 120:221-232.
- Kris-Etherton PM, Hecker KD, Bonanome A, Coval SM, Binkoski AE, Hilpert KFA, Griel E, Etherton TD (2002) Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. American J Med, 113(9) Supp. (2): 71-88.
- McLachlan JA (1993) Functional toxicology: a new approach to detect biologically active xenobiotics. Environ Health Perspect, 101: 386-387.
- Colborn T, Clement C (1992) Chemically-induced alterations in sexual and functional development: the wildlife/human connection. Princeton, NJ: Princeton Sci Publications.
- Skakkebaek NE, Rajpert-De Meyts E, Main KM (2001) Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum Reprod, 16: 972-978.
- Ademollo N, Ferrara F, Delise M, Fabietti F, Funari E (2008) Nonylphenol and octylphenol in human breast milk. Environ Internat, 34: 984-987.
- Dórea José G (2009) Alkylphenols and other pollutants contaminate human milk as well as cow's milk: formula feeding cannot abate exposure in nursing infants. Environ Internat, 35(2):451.
Details
Primary Language
Turkish
Subjects
-
Journal Section
-
Publication Date
March 1, 2009
Submission Date
July 23, 2014
Acceptance Date
-
Published in Issue
Year 2009 Volume: 2 Number: 1
APA
Uğuz, C., İşcan, M., & Togan, İ. (2009). Alkylphenols in the Environment and Their Adverse Effects on Living Organisms. Kocatepe Veterinary Journal, 2(1), 49-58. https://izlik.org/JA42WK59FL
AMA
1.Uğuz C, İşcan M, Togan İ. Alkylphenols in the Environment and Their Adverse Effects on Living Organisms. kvj. 2009;2(1):49-58. https://izlik.org/JA42WK59FL
Chicago
Uğuz, C, M İşcan, and İ Togan. 2009. “Alkylphenols in the Environment and Their Adverse Effects on Living Organisms”. Kocatepe Veterinary Journal 2 (1): 49-58. https://izlik.org/JA42WK59FL.
EndNote
Uğuz C, İşcan M, Togan İ (March 1, 2009) Alkylphenols in the Environment and Their Adverse Effects on Living Organisms. Kocatepe Veterinary Journal 2 1 49–58.
IEEE
[1]C. Uğuz, M. İşcan, and İ. Togan, “Alkylphenols in the Environment and Their Adverse Effects on Living Organisms”, kvj, vol. 2, no. 1, pp. 49–58, Mar. 2009, [Online]. Available: https://izlik.org/JA42WK59FL
ISNAD
Uğuz, C - İşcan, M - Togan, İ. “Alkylphenols in the Environment and Their Adverse Effects on Living Organisms”. Kocatepe Veterinary Journal 2/1 (March 1, 2009): 49-58. https://izlik.org/JA42WK59FL.
JAMA
1.Uğuz C, İşcan M, Togan İ. Alkylphenols in the Environment and Their Adverse Effects on Living Organisms. kvj. 2009;2:49–58.
MLA
Uğuz, C, et al. “Alkylphenols in the Environment and Their Adverse Effects on Living Organisms”. Kocatepe Veterinary Journal, vol. 2, no. 1, Mar. 2009, pp. 49-58, https://izlik.org/JA42WK59FL.
Vancouver
1.C Uğuz, M İşcan, İ Togan. Alkylphenols in the Environment and Their Adverse Effects on Living Organisms. kvj [Internet]. 2009 Mar. 1;2(1):49-58. Available from: https://izlik.org/JA42WK59FL
