Bıldırcınlarda (Coturnix coturnix japonica) Anestezi için Propofol-Ketamine Kombinasyonunun İntravenöz ve İntraosseöz Uygulanmasının Karşılaştırılması

Abstract

This experiment was conducted to compare the use of intraosseous (IO) and intravenous (IV) propofol-ketamine combination on clinical and cardiorespiratory parameters. The experiment was carried out on twenty clinically healthy mature male quails (Coturnix coturnix japonica). Quails divided into two groups. The first group (n=10) received 10 mg/kg Propofol-30 mg/kg Ketamine IV and second group (n=10) received 10 mg/kg Propofol-30 mg/kg IO. Each quail were monitored for heart rate, respiratory rate, cloacal temperature and electrocardiography. While the duration time of anesthesia in IV group was significantly shorter than IO group (p<0.05), no significant differences were recorded as regard the onset of anaesthesia in two groups. There were no significant differences obtained in heart rate (HR), respiratory rate (RR) and cloacal temperature (CT) between groups in recorded time points during anesthesia. Intraosseous administration of propofol-ketamine combination was seen as an alternative route to intravenous way, for it was shown similar changes in both IV and IO group in terms of clinical and physiological parameters. Moreover, use of propofol-ketamine combination for induction and maintenance of anesthesia was safe and reliable anesthetic combination that can be effectively used for quails. ●●● Bıldırcınlarda (Coturnix coturnix japonica) Anestezi için PropofolKetamine Kombinasyonunun İntravenöz ve İntraosseöz Uygulanmasının Karşılaştırılması

Keywords

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Comparision of Intravenous and Intraosseous Administration of Propofol-Ketamine Combination for Anesthesia in Quails (Coturnix coturnix japonica

Abstract

Bu çalışmada propofol-ketamin kombinasyonunun intravenöz (IV) ve intraosseal (IO) yolla uygulamasıyla klinik ve kardiyo-respiratorik parametreler üzerine olan etkileri karşılaştırılmıştır. Çalışma klinik olarak sağlıklı bulunan 20 adet erkek, olgun bıldırcın (Coturnix coturnix japonica) üzerinde yürütülmüştür. Bıldırcınlar iki gruba ayrılarak birinci gruba (n=10) 10 mg/kg Propofol-30 mg/kg Ketamin IV olarak uygulanırken ikinci gruba (n=10) ise 10 mg/kg Propofol-30 mg/kg Ketamin IO uygulandı. Her bir bıldırcın monitörize edilerek kalp atım sayısı (HR), solunum sayısı (RR), kloakal ısı (CT) ve elektrokardiyogramları (ECG) alınarak izlendi. Anestezi süresi IV grubunda IO gruptan önemli derecede daha kısa bulunurken (p<0.05), anestezinin başlangıç süresi açısından bir fark bulunmadı. Ayrıca gruplar arasında HR, RR, CT bakımından istatistiksel olarak anlamlı bir fark yoktu. Sonuç olarak propofolketamin kombinasyonunun IO yolla uygulanması IV yola bir alternatif olarak düşünülebilir. Çünkü klinik ve fizyolojik parametreler bakımından hem IV hem de IO gruptaki bulgular benzerlik gösterdi. Ayrıca, anesteziye giriş ve anestezi süresince propofol-ketamin kombinasyonu kullanımı kanatlı hayvanlar için bir model olarakdüşünülen bıldırcınlarda da etkin bir biçimde kullanılabilecek bir anestezik kombinasyonu olarak düşünülebilir.

Keywords

• Bıldırcın İntraosseöz İntravenöz Ketamin Propofol

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