The Effect of Platelet-Rich Fibrin (PRF) on Wound Healing in A Dog with Comorbidities

Abstract

Platelet-rich fibrin (PRF) is an autogenous material produced from the patient's own platelets, used to improve wound healing and tissue regeneration. In this case report, the effect of PRF on wound healing is investigated in a dog with tissue damage associated with infection by different pathogens (Anaplasma, Canine Coronavirus, Pneumonia and Citruvite crystals). PRF was locally applied to the wound area for 21 days, and it was observed that the wound area and the underlying bone tissue healed without any necrotic tissue. It has been concluded that PRF accelerates wound healing and tissue regeneration in material loss tissue injuries accompanied by a multifactorial disease in this case.

Keywords

• Anaplasma
• Canine
• Coronavirus
• Multifactorial disease
• Platelet-rich fibrin

Komorbidli bir Köpekte Plateletten Zengin Fibrin’in (PRF) Yara İyileşmesi Üzerindeki Etkisi

Öz

Platelet zengin fibrin (PRF) hastanın kendi trombositlerinden üretilen otojen bir materyaldir ve yara iyileşmesini ve doku rejenerasyonunu iyileştirmek için kullanılır. Bu vakada, farklı patojenlerle (Anaplasma, Canine Coronavirus, Pnömoni ve Sitrüvit Kristalleri) ilişkili doku hasarı olan bir köpekte PRF'nin yara iyileşmesi üzerindeki etkisi araştırılmıştır. PRF, yara bölgesine lokal olarak 21 gün boyunca uygulanmış ve yara bölgesi ile altta yatan kemik dokuda herhangi bir nekrotik doku olmadan iyileştiği gözlemlenmiştir. Bu durumda PRF'nin, multifaktöriyel bir hastalık tablosu ile birlikte oluşan doku kayıplı yaralanmalarda yara iyileşmesini ve doku rejenerasyonunu hızlandırdığı sonucuna varılmıştır.

Anahtar Kelimeler

• Anaplazma
• Köpek
• Multifaktöriyel hastalık
• Platelet zengin fibrin

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