Ketozisli İneklerde Tümör Nekrosis Faktör-Alfa, Kolesterol, BHBA, NEFA ve Asetilkolinesteraz Düzeylerinin Değerlendirilmesi

Abstract

Yapılan bu çalışmada ketozisli ineklerde serum beta hidroksi bütirik asit, glikoz, total protein, trigliserit, kolesterol, nonesterifie fatty acids, asetilkolinesteraz ve tümör nekroz faktör-α düzeyleri araştırıldı. Yapılan çalışmanın materyalini 3-7 yaş aralığında 10 adet ketozisli ve 10 adet sağlıklı olmak üzere toplam 20 adet holstein ırkı inek oluşturdu. Ketozis hastalığı bulunan ve sağlıklı gruptaki ineklerde serum nonesterifie fatty acids, beta hidroksi bütirik asit, aspartat aminotransferaz, total protein, glikoz, kolesterol, trigliserit, asetilkolinesteraz ve tümör nekroz faktör-α düzeyleri ölçüldü. Ketozisli ineklerde asetilkolinesteraz, glikoz, tümör nekroz faktör-α, nonesterifie fatty acids, trigliserit düzeyleri sağlıklı kontrol grubuna göre istatistiksel olarak önemli çıkmadığı, ketozisli ineklerde total protein ve kolesterol düzeyleri düşük çıkarken, beta hidroksi bütirik asit ve aspartat aminotransferaz seviyeleri sağlıklı ineklere göre yükseldiği belirlendi. Sonuç olarak ketozisli ineklerde asetilkolinesteraz ve tümör nekroz faktör-α düzeylerinin araştırılması hastalığın biyokimyasal bulgularına faydalı olabileceği kanaatine varıldı.

Keywords

• Asetilkolinesteraz
• Beta hidroksi bütirik asit
• İnek
• Ketozis
• Tümör nekrosis faktör-alfa

Evaluation of Tumor Necrosis Factor-Alfa, Cholesterol, BHBA, NEFA and Acetylcholinesterase Levels in Cows With Ketosis

Abstract

In this study serum beta-hydroxybutyric acid, glucose, total protein, triglyceride, cholesterol, non-esterified fatty acids, acetylcholinesterase and tumor necrosis factor-α were investigated in cows with ketosis. The study material consisted of 10 control and 10 group with ketosis, total 20 holstein dairy cows of 10 control and 10 groups with ketosis, a total of 20 holstein dairy cows aged between 3 and 7 years. In this study serum concentration was measured for nonesterified fatty acids, beta-hydroxybutyric acid, aspartate aminotransferase, total protein, cholesterol, triglyceride, acetylcholinesterase and tumor necrosis factor-α in the healthy group and cows with ketosis. Serum glucose, triglyceride, nonesterified fatty acids, acetylcholinesterase and tumor necrosis factor-α did not differ significantly between the two groups. Aspartate aminotransferase and beta-hydroxybutyric acid increased, while cholesterol and total protein concentration decreased in ketotic cows compared with healthy cows. Consequently, acetylcholinesterase and tumor necrosis factor-α concentrations may prove beneficial biochemical findings in cows with ketosis.

Keywords

• Acetylcholinesterase
• Beta hydroxybutyric acid
• Cow
• Ketosis
• Tumor necrosis factor-alfa

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