Mentha Spicata L. Kuru Tozunun ve Farklı Tip Ekstrelerinin Bazı Biyokimyasal Parametreler ve Total Antioksidan Kapasite Üzerine Etkileri

Abstract

Mentha spicata( peppermint), Labiatae familyasına ait bir bitkidir. İştah azalması, soğuk algınlığı, bronşit, sinüzit, ateş, mide bulantısı, kusma ve hazımsızlıkta kullanılan bitkisel bir ajandır. Flavonoid içerikli bitkilerin özellikle antioksidan etkileri yıllardır araştırılıyor olmasına karşın, kuru nane tozu ile birlikte enzimatik ve nonenzimatik antioksidanlar ile vitaminler arasındaki etkileşimleri ele alan çalışmalar yok denecek kadar azdır. Bu tez, Mentha spicata’nın bazı biyokimyasal parametrelere etkilerini ve antioksidan aktivitesini araştırmak amacıyla gerçekleştirilmiştir.

Keywords

• Mentha Spicata L.,β-karoten,Vitamin C,Glutatyon,Antioksidan

The Effect of Mentha Spicata L. Dry Powder and its Different Types Extracts on Certain Biochemical Parameters and Total Anti-oxidant Capacity

Abstract

The plant Mentha spicata, or peppermint, is member of the Labiatae family, commonly used in the treatment of loss of appetite, common cold, bronchitis, sinusitis, fever, nausea and vomiting, and indigestion as a herbal agent.Although anti-oxidant effects of flavonoid containing plants have been investigated largely, studies in their interactions with enzymatic and nonenzymatic antioxidants and vitamins together with dead mentha powder are rare.The present thesis was carried out to investigate the effects of certain biochemical parameters and Mentha spicata, on antı-oxidant levels.

Keywords

• Mentha Spicata L,β-Carotene,Vitamin C,Glutathione,Antı-Oxidant

References

1. Karadoğan T. Göller yöresinde lamiaceae familyasına dahilbitki türlerinin tespiti ve tıbbi ve aromatikdeğerlerinin belirlenmesi, Türkiye bilimsel ve Teknik araştırma kurumu 2003,
2. Fux CA, Stoodley P, Hall-Stoodley L, Costerton JW. (2003). Bacterial biofilms: A diagnostic and therapeutic challenge. Expert Rev. Anti-Infect. Ther. 1: 667–683.
3. Schachter B. (2003). Slimy business-the biotechnology of biofilms. Nat. Biotechnol. 21, 361–365.
4. Lewıs K. (2001). Riddle of biofilm resistance. Antimicrob Agents Chemother. 45: 999–1007.
5. Francis G, Kerem Z, Makkar HPS, Becker K. (2002). The Biological Action Of Saponins İn Animal Systems. Br. J.Nutr. 88: 587–605. Dündar Y. (2001). Fitokimyasallar ve Sağlıklı Yaşam. Kocatepe Tıp Dergisi. 2: 131–138.
6. Sen S, Makkar HPS, Becker K. (1998). Alfalfa saponins and their implication in animal nutrition. J.Agric. Food. Chem. 46: 131–140.
7. Bayşu Sözbilir N, Bayşu N. (2008). Biyokimya, Güneş Tıp Kitapevleri, 1. Baskı. Ankara. Arzanı A, Zeınalı H, Razmjo K. (2007). Iron and Magnesium Concentrations of Mint Accessions (Mentha spp.) Plant Physiology and Biochemistry. 45: 323–329. Eryiğit F. (2006).
8. Mentha Pulegium L. ve Salvia Tomentosa Miller Bitkilerinin Metanol Özütlerinin In Vitro Antioksidan Aktivitelerinin Belirlenmesi.Yüksek Lisans Tezi. Süleyman Demirel Üniversitesi. Fen Bilimleri Enstitüsü. Beutler E, Duron O, Kelly BM. Improved Method For The Determination of Blood Glutathione. J Lab Clin Med 1963; 61: 882–90.

9. Draper H H, Hadley M. (1990). Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 186: 421–30.
10. Kway A. (1978) A Simple Colorimetric Method For Ascorbic Acid Determination İn Blood Plasma. Clin Chim Acta ; 16: 151-157.
11. Suzukı JP, Katoh NA. (1990). A Simple and Cheap Method for Measuring Serum Vitamin A in Cattle Using Only Spectrophotometer. Jpn. .J. Vet. Sci. 52: 1281–1283.
12. Koracevic D, Koracevic G, Djordjevic V, Andrejevic S, Cosıc V. (2001) Method fort he measurment of antioxidant activity in human fluids. J Clin Pathol. 54: 356–361.
13. Cayman Chemıcal Company (2006a). Glutathione Peroxidase Assay Kit. Catalog No: 703102. 1180 E.Ellsworth Rd. Ann Arbor, MI 48108. Printed in U.S.A. 1–20.
14. Cayman Chemıcal Company(2006b). Glutathione Reductase Assay Kit. Catalog No: 703202. 1180 E.Ellsworth Rd. Ann Arbor, MI 48108. Printed in U.S.A. 1–22.
15. Samarth RM , Panwar M, Kumar M, Kumar A. (2006). Protective Effects of Mentha Piperita Linn on Benzo[a]pyrene-Induced Lung Carcinogenicity and Mutagenicity in Swiss Albino Mice. Mutagenesis. 21(1): 61–66
16. Sharma MK, Sharma A, Kumar A, Kumar M. (2007). Protective Efficacy of Leaves Extract of Mentha Piperita on Sodium Arsenite İnduced Cellular Damage in Mouse. Toxicology & toxicology Letters 172S .S71-S72.
17. Alçiçek A, Bozkurt M, and Çabuk M. (2003). The effect of essential oil combination derived from selected herbs growing wild in Turkey on broiler performance. South Afrc. J of Anim. Sci. 33(2): 89-94.
18. Mandal L, Bıswas T, and Sarkar SK. (2000). Broiler performs well on herbs or enzymes in maize diet. World Poultry-Elsevier. 16(5): 19–21.
19. Mccartney E. (2002). The natural empire strikes back. Poult. International. 41(1): 36-42.
20. Tucker L. (2002). Botanical Broilers: Plant Extracts to Maintain Poultry Performance. Feed International. 23(9): 26-29.
21. Ramakrıshna RR, Platel K, and Srınıvasan K. 2003. In vitro influence of species and spice-active principles on digestive enzymes of rat pancreas and small intestine. Nahrung. Dec; 47(6): 408-412.
22. Langhout P. (2000). New additives for broiler chickens. World Poultry-Elsevier. 16(3): 22–27.
23. Djouvınov D, Pavlov D, Ilchev A, Enev E. (1997). Peppermint (Mentha Piperita Huds) and Basil (Ocimum Basilicum L.) Etheric Oil By-Products as Roughages for Sheep Feeding. Anim. Feed Sci. Tech. 68: 287–294.
24. Oğul YT. (2006). Romatoid Artritli Hastalarda Antioksidan Tablo ve Eritrosit Membran Na+/K+ ATPaz Aktivitesinin İncelenmesi. Uzmanlık Tezi. Atatürk Üniversitesi. Erzurum.