Vitamin D Levels in Cat and Dogs With Ehlers-Danlos Syndrome: Case Series Touching Nutritional Deficiency Hypothesis

Abstract

Ehlers Danlos syndrome (EDS) reported varied animal species is a rare hereditary collagen disorder standing out  reduced strength of skin being hyperextensible, velvety and fragile. Diagnosis of also termed dermatosparaxis or cutaneous asthenia in animals is based on  classic clinical symptoms, skin extensibility index with histopathologic examination included thin, unregular seperated collagen bundles. In the presented case series enrolled different ages (1-3 years old 4 cats; and 1-5 years old 6 dogs) with both gender cats (2 males, 2 females) and dogs (4 males, 2 females) has been conferred serum 25 (OH) D3 levels associations. Just as dog and cats diagnosed with EDS found lower vitamin D levels (total 8 of 10) are considered, it has recommended in cat and dogs with EDS taking into account of vitamin D deficiency as well as some other nutritional deficiencies and giving oral vitamin D supplements with safety as human medicine. 

Keywords

• Ehlers-Danlos Syndrome,cat,dog,vitamin D

Ehlers-Danlos Sendromlu Kedi ve Köpeklerde D Vitamini Düzeyleri: Nutrisyonel Bozukluk Hipotezine Dair Olgu Serisi

Öz

Farklı hayvan türlerinde bildirilen ve derinin elastikiyetinde azalma, deride aşırı uzama, yumuşama bulgular gösteren Ehlers Danlos Sendromu (EDS) nadir görülen kalıtsal kollojen hastalığıdır. Hayvanlarda dermatosparaksis ve kutanöz astenia olarak da bilinen bu hastalığın tanısı klasik klinik bulgular, cilt uzayabilirlik indeksi ile histopatolojide kalın, düzensiz ayrılmış kollojen demetlerinin görülmesine dayanmaktadır. Farklı yaş (n=4 kedi; 1-3 yaşlı ile n=6 köpek 1-5 yaşlı), her 2 cinsiyetten kedi (2 erkek, 2 dişi) ve köpeğin (4 erkek, 2 dişi) dahil edildiği olgu serisinde serum 25 (OH) D3 seviyeleri ile ilişkileri sunulmaktadır. EDS tanısı konulan kedi ve köpeklerde bulunan düşük vitamin D seviyeleri (toplamda 8/10) düşünüldüğünde EDS’ li kedi ve köpeklerde diğer beslenme eksikliklerinin yanı sıra vitamin D yetersizliğinin de göz önüne alınması gerektiği ve beşeri hekimlikte olduğu gibi oral vitamin D takviyesinin güvenle verilebileceği önerilmektedir. 

Anahtar Kelimeler

• Ehlers-Danlos Sendromu,kedi,köpek,vitamin D

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