Antibiotic Resistance of Stenotrophomonas maltophilia Strains Isolated from Horses

Year 2019, , 384 - 388, 31.12.2019

Uçkun Sait Uçan , Bilal Osamah Mohammed Murat Yiğit

https://doi.org/10.30607/kvj.583479

Abstract

Stenotrophomonas maltophilia
is a member of gamma proteobacteria that has been frequently isolated from
humans as well as from animals. One of the most outstanding feature of S. maltophilia is its antibacterial
resistance that is basicly controlled by various pathways including intrinsic
manner. By this study we aimed to evaluate the interaction of S. maltophilia suspected equine strains
with various antibiotics in the presence of Thymoquinone in vitro. Disc diffusion technique was used for measuring
interactions between the thymoquinone and others. No measurable inhibition zone
for synergistic or antagonistic effect between the thymoquinone and test
antibiotics was observed. However, the thymoquinone itself has an antibacterial
potential.

Keywords

Stenotrophomonas maltophilia, Antibiotic, horse, resistance

Atlardan İzole Edilen Stenotrophomonas maltophilia Suşlarının Antibiyotik Direnci

Abstract

Stenotrophomonas maltophilia
gamma proteobacteria içerisinde yer alan ve hem insanlardan hem de hayvanlardan
sık izole edilen bir bakteri türüdür. S.
maltophilia’nin en dikkat çeken özelliklerinden birisi bakterinin intrinsik
mekanizmalar da dahil olmak üzere çeşitli şekillerde geliştirdiği yüksek
antibiyotik direncidir. Bu çalışma ile atlardan izole edilmiş olan S. maltophilia’nın timokionon ile
çeşitli antibiyotiklerin beraber kullanıldıklarındaki etkileşimini ölçmek
amaçlandı. Ne sinerjizm ne de antogonizm şeklinde bir etkileşim ölçülmedi.
Ancak timokiononun S. maltophilia
suşları üzerinde antibakteriyel etkisi tespit edildi.. 

Keywords

Stenotrophomonas maltophilia, Antibiyotik, at, direnç

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