Aelurostrongylus abstrusus infection and radiographic findings in a kitten

Abstract

A two-month-old female kitten suffering from respiratory signs, lethargy, and anorexia for fifteen days was brought to Balikesir University Small Animal Internal Medicine Clinics of Veterinary Faculty. During pulmonary auscultation, stridors in the cranial pulmonary lobes were detected. Laterolateral and ventrodorsal radiographs were obtained. A live larva of Aelurostrongylus abstrusus was also detected in the patient's direct fecal smear. The patient had recovered after treated with suitable antibiotics and anthelmintics. The parasite is determined in young adults or older cats, and it can cause serious infection. It can cause serious radiological findings in the lungs in kittens besides clinical symptoms. In conclusion, a differential diagnosis list in kittens that have dyspnea and serious pulmonary radiological findings must involve A. abstrusus infection.

Keywords

• Aelurostrongylus abstrusus
• kitten
• nematoda
• thorax radiography

Bir Yavru kedide Aelurostrongylus abstrusus enfeksiyonu ve radyografik bulgular

Abstract

Balıkesir Üniversitesi Veteriner Fakültesi Küçük Hayvan İç Hastalıkları Kliniği'ne Kliniği'ne 15 gündür solunum bulguları, uyuşukluk ve iştahsızlık şikayeti olan iki aylık dişi yavru kedi getirildi. Pulmoner oskültasyon sırasında, kraniyal pulmoner loblarda stridorlar tespit edildi. Hastanın laterolateral ve ventrodorsal radyografileri çekildi. Hastanın direkt dışkı yaymasında da canlı bir Aelurostrongylus abstrusus larvası tespit edildi. Hasta, uygun antibiyotik ve antelmintiklerle tedavi edildikten sonra iyileşti. Genç yetişkinlerde veya yaşlı kedilerde belirlenen parazit ciddi enfeksiyonlara neden olabilir. Ayrıca kedilerde klinik semptomların yanı sıra akciğerlerde ciddi radyolojik bulgulara neden olabilir. Sonuç olarak, nefes darlığı ve akciğerlerinde ciddi radyolojik bulguları olan yavru kedilerde ayırıcı tanı listesi A. abstrusus enfeksiyonunu içermelidir.

Keywords

• Aelurostrongylus abstrusus
• nematod
• toraks radyografisi
• yavru kedi

References

1. Anderson RC. The superfamily Metastrongyloidea. In: Nematode Parasites of Vertebrates. Their Development and Transmission, 2nd ed, CABI Publishing, Guilford. 2000; pp. 163–164.
2. Annoscia G, Latrofa MS, Campbell BE, Gianelli A, Ramos RAN, Dantas-Torres F, Brianti E, Otranto D. Simultaneous detection of the feline lungworms Troglostrongylus brevior and Aelurostrongylus abstrusus by a newly developed duplex-PCR. Veterinary Parasitology. 2014; 199: 172–178.
3. Atasever A, Yazar S. Aelurostrongylus abstrusus Pneumonia in an Immunosuppressed Cat. Türkiye Parazitoloji Dergisi. 2009; 33: 89 – 91.
4. Barrs VR, Swinney GR, Martin P, Nicoll RG. Concurrent Aelurostrongylus abstrusus infection and salmonellosis in a kitten. Australian Veterinary Journal. 1999; 77: 229–232.
5. Blagburn BL, Hendrix CM, Lindsay DS, Vaughan JL. Anthelmintic efficacy of ivermectin in naturally parasitized cats. American Journal of Veterinary Research. 1987; 48: 670–672.
6. Burgu A, Sarımehmetoğlu O. Aelurostrongylus abstrusus infection in two cats. Veterinary Record. 2004; 154: 602-604.
7. Briggs KR, Yaros JP, Liotta JL, Lucio-Foster A, Lee AC, Bowman DD. Detecting Aelurostrongylus abstrusus-specific IgG antibody using an immunofluorescence assay. Journal of Feline Medicine and Surgery. 2013; 15: 1114–1118.
8. Dennler M, Bass DA, Gutierrez-Crespo B, Schnyder M, Guscetti F, DiCesare A, Deplazes A, Kircher PR, Glaus TM. Thoracic Computed Tomography, Angiographic Computed Tomography, And Pathology Findings In Six Cats Experimentally Infected With Aelurostrongylus Abstrusus. Veterinary Radiology and Ultrasound. 2013; 54, 459–469.

9. Elsheikha HM, Schnyder M, Traversa D, Di Cesare, A, Wright I, Lacher DW. Updates on feline aelurostrongylosis and research for the next decade. Parasitological Vectors. 2016; 9: 389.
10. Foster SF, Martin P, Allan GS, Barrs, VR, Malik R. Lower respiratory tract infections in cats: 21 cases (1995–2000). Journal of Feline Medicine and Surgery. 2004a. 6: 167–180.
11. Foster SF, Martin P, Braddock JA, Malik R. A retrospective analysis of feline bronchoalveolar lavage cytology and microbiology (1995–2000). Journal of Feline Medicine and Surgery. 2004; 6: 189–198.
12. Gerdin JA, Slater MR, Makolinski KV, Looney AL, Appel LD, Martin NM, McDonough SP. Post-Mortem Findings in 54 Cases of Anesthetic Associated Death in Cats from Two Spay—Neuter Programs in New York State. Journal of Feline Medicine and Surgery. 2011; 13: 959-966.
13. Grandi G, Calvi LE, Venco L, Paratici C, Genchi C, Memmi D, Kramer LH. Aelurostrongylus abstrusus (cat lungworm) infection in five cats from Italy. Veterinary Parasitology. 2005; 134: 177–182.
14. Heuer L, Petry G, Pollmeier, M. Schaper R, Deuster K, Schmidt H, Katrin Blazejak, Strube C, Di Cesare A, Traversa D, Schynder M, McKay-Demeler, Himmelstjerna GS, Mangold-Gehring S, Böhm C. Efficacy of imidacloprid 10%/moxidectin 1% spot-on formulation (Advocate®) in the prevention and treatment of feline aelurostrongylosis. Parasites Vectors. 2020; 13, 65.
15. Hobmaier M, Hobmaier A. Intermediate Hosts of Aelurostrongylus abstrusus of the Cat. Proceedings of the Society for Experimental Biology and Medicine. 1935; 32: 1641–1647.
16. Holmes RA. Feline Dirofilariasis. Veterinary Clinics North America Small Animal Practice 1993; 23: 125–138. Kirkpatrick CE, Megella C. Use of ivermectin in treatment of Aelurostrongylus abstrusus and Toxocara cati infections in a cat. Journal of American Veterinary Medical Association. 1987; 190: 1309–1310.
17. Martin Knaus, S. Theodore Chester, Joseph Rosentel, Axel Kühnert, Steffen Rehbein. Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against larval and adult stages of the cat lungworm, Aelurostrongylus abstrusus, Veterinary Parasitology, 2014; 202: 64-68.
18. López C, Panadero R, Paz A, Sanchez-Andrade R, Diaz P, Diez-Paños P, Morrondo P. Larval development of Aelurostrongylus abstrusus (Nematoda, Angiostrongylidae) in experimentally infected Cernuella (Cernuella) virgata (Mollusca, Helicidae). Parasitological Research. 2005; 95: 13–16.
19. Losonsky JM, Thrall DE, Prestwood AK. Radiographic evaluation of pulmonary abnormalities after Aelurostrongylus abstrusus inoculation in cats. American Journal of Veterinary Research, 1983; 44: 478-482.
20. Mahaffey MB. Radiographic-Pathologic Findings In Experimental Aelurostrongylus Abstrusus Infection In Cats. Veterinary Radiology. 2005; 20: 81.
21. Pechman RD. Newer Knowledge of Feline Bronchopulmonary Disease. Veterinary Clinics North America Small Animal Practice 1984; 14: 1007–1019.
22. Taubert A, Pantchev N, Vrhovec MG, Bauer C, Hermosilla C. Lungworm infections (Angiostrongylus vasorum, Crenosoma vulpis, Aelurostrongylus abstrusus) in dogs and cats in Germany and Denmark in 2003-2007. Veterinary Parasitology 2009; 159: 175–180.
23. Traversa D, Cesare A, Di Milillo P, Iorio R, Otranto D. Aelurostrongylus abstrusus in a feline colony from central Italy : clinical features, diagnostic procedures and molecular characterization. Parasitological Research. 2008a; 103: 1191-1196.
24. Traversa D, Di Cesare A, Conboy G. Canine and feline cardiopulmonary parasitic nematodes in Europe: Emerging and underestimated. Parasitological Vectors. 2010 3, 1-22.
25. Traversa D, Lia RP, Iorio R, Boari A, Paradies P, Capelli G, Avolio S, Otranto D. Diagnosis and risk factors of Aelurostrongylus abstrusus (Nematoda, Strongylida) infection in cats from Italy. Veterinary Parasitology 2008b; 153: 182–186.
26. Tüzer E, Toparlak M, Gargili A, Keleş V, Esatgil M. A case of Aelurostrongylus abstrusus infection in a cat in İstanbul, Turkey and its treatment with moxidectin and levamisole. Turkish Journal of Veterinary and Animal Sciences 2002; 26: 411–414.
27. Yildiz K, Duru SY, Gokpinar S. Alteration in blood gases in cats naturally infected with Aelurostrongylus abstrusus. Journal of Small Animal Practice. 2011; 52: 376-379.
28. Willard MD, Roberts RE, Allison N, Grieve RB, Escher K. Diagnosis of Aelurostrongylus abstrusus and Dirofilaria immitis infections in cats from a human shelter. Journal of American Veterinary Medical Association. 1988; 192: 913-916.
29. Zottler EM, Strube C, Schnyder M. Detection of spesific antibodies in cats infected wiht the lung nematode. Aelurostrongylus Abstrusus Veterinary Parasitology. 2017; 235: 75-82.