The Efficacy of Oral Administration of Clinoptilolite Against Naturally Occuring Giardiasis in Calves

Year 2016, Volume: 9 Issue: 4, 288 - 293, 01.12.2016

Deniz Alıç Ural , Nuran Aysul Mehmet Gültekin

Abstract

The aim of the present study was to evaluate the efficacy of clinoptilolite against naturally occurring giardiasis in calves. A total of twelve calves naturally infected with G. duodenalis at the age of 16 to 34 days, of both sexes were enrolled into the study from two different farms of Aydin province. Calves were randomly assigned into two groups (n=6). Group I received orally clinoptilolite at a dosage of 1 g/kg for ten days whereas calves in Group II were left as control and received no drugs. Efficacy of clinoptilolite was determined by microscopically examination of faecal samples on days 0, 7 and 14. The percentage reduction in cyst excretion after clinoptilolite treatment was 74% on day 7 and 84% on day 14. Geometric means of the number of excreted cysts were not reduced significantly in control group between day 0 (26344) and 14 (22775). In conclusion, it may be concluded that oral administration of clinoptilolite for ten days may help to reduce the excretion of cysts in calves with giardiasis.

Keywords

Calf, Giardiasis, Clinoptilolite

Buzağılarda Oral Yolla Klinoptilolit Uygulamasının Doğal Yolla Oluşan Giardiazis’e Karşı Etkinliği

Abstract

Bu çalışmada klinoptilolitin buzağılarda doğal yolla oluşan giardiazise karşı etkinliğinin belirlenmesi amaçlandı. Aydın ili sınırları içerisinde iki farklı süt sıg ırı is letmesinde ishal anamnezi bulunan G. duodenalis ile doğal enfekte her iki cinsiyetten ve 16-34 günlük 12 buzag ı çalışma kapsamına alındı. Buzag ılar her grupta n=6 olacak s ekilde randomize olarak 2 ayrı gruba ayrılarak I. gruba 1 g/kg dozda 10 gün oral yolla klinoptilolit (Natmin-9000) uygulanırken, II. gruptaki olgulara hiçbir ilaç uygulaması yapılmayarak kontrol grubu olarak bırakıldı. Buzag ılarda klinoptilolit sag altımının etkinliği 0., 7. ve 14. günlerde toplanan dıs kı örneklerinin mikroskobik muayenesiyle değerlendirildi. Gram dışkıda kist atılımındaki azalma değerlendirildiğinde klinoptilolit giardiazise karşı 7. günde % 74, 14. günde % 84 etkinlik sağladı. Buna karşın kontrol grubunda 0. gün ile (26344) 14. günlerde (22775) kist atılımının geometrik ortalamalarındaki azalmanın belirgin olmadığı görüldü. Sonuç olarak giardiazisli buzağılarda oral yolla 10 gün uygulanan klinoptilolitin kist atılımının azaltılmasına yardımcı olabileceği söylenebilir.

Keywords

Buzağı, Giardiasis, Klinoptilolit

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