Assessment of Echocardiographic Ejection Fraction and Fractional Shortness at Different Stages of Canine Visceral Leishmaniasis

Year 2018, Volume: 11 Issue: 1, 45 - 52, 01.03.2018

Canberk Balıkcı , Kerem Ural

Abstract

In this study, it was aimed to evaluate EF and FS parameters at different stages of canine visceral leishmaniasis to benefit in diagnosis and treatment monitoring. A total of 35 dogs, 28 of which were infected with L. infantum and 7 of which were healthy, constituted the material of study. VL diagnosis was confirmed with test kit positivity with fast ELISA on blood samples. VL dogs eligible for inclusion into study were evaluated in 4 different groups (n = 7, each group), according to "LeishVet Working Group". ECHO, studies were performed on the right parasternal short axisand EF and FS parameters were detected. In control group, EF values (%) was found between 48 and 74, FS(%) value between 24 and 38. EF value was found between 59 and 74,FS valuewas between 31 and 42 in group I. EF value was found between 58 and 93, FS value was between 29 and 63 in group II. EF value was foundbetween 35.3 and 93.8, FS value wasbetween 16.4 and 50 in group III. EF value was between 52 and 82, FS value was between 27 and 50 in group IV. As a result, when we considered the LWG, it can be said that echocardiographic evaluation [reduction in FS, EF (systolic dysfunction)] should be performed into account in CVL dogs. It may be beneficial to focus on cardiac changes contributing to the intravital diagnosis in CVL dogs and to apply the necessary additional treatment protocols.

Keywords

Leishmaniasis, echocardiography, ejection fraction, fractional shorthening, dog

Canine Visceral Leishmaniasis’in Farklı Evrelerinde Ekokardiyografik Ejeksiyon Fraksiyonu ve Fraksiyonel Kısalmanın Değerlendirilmesi

Abstract

Bu çalışmada Canine Visceral Leishmaniasisin farklı evrelerinde ejeksiyon fraksiyonu (EF) ve fraksiyonel kısalma (FS) parametrelerinin değerlendirilerek tanıda ve sağaltım monitörizasyonunda fayda sağlaması amaçlanmıştır. Araştırmanın materyalini, 28’i L. infantum ile doğal enfekte 7’si de sağlıklı olmak üzere toplam 35 köpek oluşturdu.Klinik bulgular temelinde VL şüpheli tanısı konulan köpeklerde kan örneğinde hızlı ELİSA prensibiyle çalışan test kiti pozitifliği ile VL tanısı kesinleştirildi. Çalışmaya dahil edilmesi uygun görülen VL’li köpekler, “LeishVet Çalışma Grubu”nun önerdiği evreleme dikkate alınarak 4 farklı gruptan (her grupta n=7) birinde değerlendirildi. EKO, M mod incelemeler sağ parasternal kısa eksende gerçekleştirildi ve sol ventrikül EF ve FS parametreleri belirlendi.Çalışmadaki kontrol grubu olguların EF değeri (%) 48 ile 74 ve FS değeri (%) 24 ile 38,olduğu saptandı. I. gruptaki olgularda EF değeri (%) 59 ile 74 ve FS değeri (%) 31 ile 42 arasında olduğu görüldü. II. gruptaki olgularda EF değeri (%) 58 ile 93 ve FS değeri (%) 29 ile 63 arasında idi. III. gruptaki olgularda EF değeri (%) 35.3 ile 93.8 ve FS değeri (%) 16.4 ile 50 arasında değişmekteydi. IV. gruptaki olgularda ise EF değeri (%) 52 ile 82 ve FS değeri (%) 27 ile 50 arasında olduğu belirlendi. Sonuç olarak Leishvet Çalışma Grubunun serolojik, klinik ve laboratuvar bulguları dikkate alındığında 4 farklı grupta (evre I-IV) yer alan olgularımızda ekokardiyografik [FS’de ve EF’de azalma (sistolik disfonksiyon)] değerlendirmenin CVL’li köpeklerde dikkate alınması gerektiği söylenebilinir. CVL’li köpeklerde intravital diyagnoza katkı sağlayan kardiyak değişikliklerin üzerinde önemle durulması ve gerekli ilave sağaltım protokollerinin uygulanması fayda sağlayabilir.

Keywords

Leismaniasis, ekokardiyografi, ejeksiyon fraksiyonu, fraksiyonel kısalma, köpek

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