Giardia Duodenalis ile Doğal Enfekte Köpeklerde Klinoptilolit ile Antiparaziter Kür Sağlanabilir Mi?

Year 2019, Volume: 12 Issue: 3, 305 - 309, 30.09.2019

Adnan Ayan , Songül Erdoğan

https://doi.org/10.30607/kvj.576233

Abstract

Bu çalışmanın amacı doğal zeolit bileşeni olan
klinoptilolitin köpeklerde doğal olarak şekillenen giardiazise karşı
antiparaziter etkinliğinin belirlenmesidir. Aydın bölgesinde bulunan doğal
olarak Giardia duodenalis ile enfekte
olan sahipli ve ishalli her iki cinsiyetten 6-44 aylık yaştaki 7 enfekte köpek
çalışmada kullanıldı. İki ayrı gruba ayrılan çalışma materyali olarak I.
gruptakilere 10 gün oral yolla 2 g/kg dozda klinoptilolit uygulanırken, II.
grupta bulunan köpeklerin kontrol grubu olarak kalmaları sağlandı. Köpeklerde
klinoptilolitin antiparazitik etkinliği 0. 3.
7. ve 10. günlerde rektal
yolla alınan dışkı örneklerinin mikroskobik incelenmesiyle değerlendirildi. Gram
dışkı başına kist miktarındaki azalma göz önünde bulundurulduğunda
anti-giardial amaçla kullanılan klinoptilolitin 10. günde giardiazise karşı
kist atılımında %99 etkinlik sağladığı belirlendi. Sağaltım grubunda sırası ile
0.,3., 7. ve 10. günlerde kist sayılarına ait geometrik ortalamalar 200552.4,
37.8, 113.3, 10.4 şeklinde belirlendi. kontrol grubunda ise 0. gün ile
(195099,4) 10. günlerdeki (174436,1) kist atılımının geometrik
ortalamalarındaki fazla değişimin göstermediği saptandı. Netice itibarı ile
giardiazisli köpeklerde klinoptilolitin kist atılımını etkin şekilde azalttığı
ve önerilen dozda herhangi bir yan etkiye neden olmaksızın kullanılabileceği
söylenebilir.

Keywords

Giardia duodenalis, Klinoptilolit, Köpek

Thanks

Çalışmanın dizaynı, yönetimi ile grupların tasvirinde yadsınmaz rolü olan değerli Hocam Prof. Dr. Kerem URAL’a, istatistiksel verilerin tasarlanmasında Dr. Öğretim üyesi Hasan ERDOĞAN’a müteşekkirim.

Could Antiparasitic Cure with Clinoptilolite be Achieved in Dogs Naturally Infected with Giardia Duodenalis?

Abstract

The aim of this study was to determine the antiparasitic efficacy of the natural zeolite component, clinoptilolite, against naturally occurring giardiasis in dogs. Seven infected dogs, aged 6-44 months of age, both sexually owned and diarrhea infected with Giardia duodenalis in the Aydın region were used in the study. Group I was administered clinoptilolite orally for 10 days at a dose of 2 g / kg. Group II dogs were provide to stay in the control group. The antiparasitic efficacy of clinoptilolite in dogs was evaluated by microscopic examination of stool samples collected at the beginning 0, 3rd, 7th and 10th day by rectal route. Considering the reduction in cyst excretion per gram feces, clinoptilolite used for anti-giardial purposes provided 99% efficacy in cyst excretion at 10th day. In the treatment group, the mean geometric averages of cyst counts were determined as 200552.4, 37.8, 113.3, 10.4, respectively, on days 0, 3, 7 and 10. On the other hand, in the control group, no significant change was observed in the geometric mean of cyst ruble excretion on day 0 (195099,4) 10 days (174436,1). It can be said that clinoptilolite effectively decreases cyst excretion in dogs with giardiasis and can be used in the recommended dose without causing any side effects.

Keywords

Giardia duodenalis, Clinoptilolite, Dog

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