Samsun İli ve Çevresindeki Atopik Dermatitisli Köpeklerde Serum Spesifik IgE Tespiti ile Alerjen Tayini

Year 2019, Volume: 12 Issue: 4, 413 - 423, 31.12.2019

Öykü Barılı , Didem Pekmezci

https://doi.org/10.30607/kvj.599782

Cited By: 2

Abstract

Bu çalışma ile Samsun ili ve çevresindeki
Atopik Dermatitis (AD)’li köpeklerde ilk kez serum spesifik immunoglobin E
(IgE) ile alerjen profillerinin belirlenmesi amaçlanmıştır. Değişik ırk, cinsiyet ve yaşlardaki 21 adet köpeğe Favrot Kriterleri ile
AD teşhisi konulmuştur. Köpeklere ait serum örnekleri serolojik olarak 20
farklı alerjene spesifik IgE yönünden incelenmiştir. AD’li köpeklerde 20 farklı alerjenin görülme oranlarına cinsiyet, yaş ve beslenme şekillerinin
etkisi araştırılmıştır. Samsun ili ve çevresindeki AD’li köpeklerdeki farklı
alerjen profilleri arasında en yüksek %95 oranında ev tozu akarı Dermatophagoides
farinae seropozitifliği
saptanmıştır. Bununla birlikte köpeklerde farklı oranlarda diğer alerjenlere
yönelik seropozitiflik saptanmıştır. Dişi köpeklerde erkek köpeklere oranla sadece Ctenocephalides spp. seropozitifliğinin yüksek olduğu istatistiksel olarak tespit edilmiştir
(p<0,05). Bununla birlikte AD’li köpeklerde yaş ve beslenme şekillerinin
alerjen görülme sıklığına etkisinin olmadığı tespit edilmiştir (p>0,05). Samsun ili ve çevresindeki AD’li
köpeklerde ev tozu ile depo akarlarının serum spesifik IgE değerlerinin çok
yüksek oranlarda pozitiflik verdiği saptanmıştır. 

Keywords

Alerjen, Atopik dermatitis, Köpek, Samsun, Spesifik IgE

Supporting Institution

Ondokuz Mayıs Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi

Project Number

PYO.VET.1904.17.016

Thanks

Bu çalışma, Ondokuz Mayıs Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimince PYO.VET.1904.17.016 proje numarası ile desteklenmiş ve Öykü Barılı’nın aynı isimli Yüksek Lisans Tezi’nden özetlenmiştir. Ayrıca çalışmanın istatistiğini yapan Sayın Prof.Dr. Filiz Akdağ’a şükranlarımızı sunarız.

Allergen Determination with Detection of Serum Specific IgE in Dogs with Atopic Dermatitis from Samsun and Vicinity

Abstract

It is aimed to detect allergen determination via serum specific
immunoglobulin E (IgE) for the first time in dogs diagnosed as Atopic
Dermatitis (AD) from Samsun and vicinity within this present study. Twenty one dogs with
different age, breed and gender
diagnosed with AD based up on the Favrot’s criteria. Serum samples of the dogs
were analyzed by detection of serum specific IgE for determination of 20
different allergens. The effects of gender, age and the feeding routes for
those 20 different allergens separately were analyzed. Based up on the grading
of the allergens detected in 21 dogs with AD from Samsun and
vicinity; results reflects that
Dermatophagoides farinae was stated as first degree within a very high seropositivity rate
(95%). Moreover, in varying degree of seropositivitiy rates of other allergens
were also detected. Females showed statistically (p<0.05) higher positivity rate to the 20^th
allergen, Ctenocephalides spp. more than
males. Furthermore, we did not found any significant effects of age and feeding
routes on the allergens in the dogs with AD (p>0.05). Dogs with AD from
Samsun and vicinity had very high serum specific IgE levels against to the
house dust and storage mites.

Keywords

Allergen, Atopic dermatitis, Dog, Samsun, Specific IgE

Project Number

PYO.VET.1904.17.016

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