Research Article
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Seroprevalence of Paratuberculosis in Cattle in Ardahan Region

Year 2020, Volume: 13 Issue: 4, 327 - 331, 31.12.2020
https://doi.org/10.30607/kvj.741292

Abstract

In this study, it was aimed to determine the prevalence of paratuberculosis the dairy cattle of Ardahan province. 11 focuses randomly selected from the Ardahan center and its districts and a total of 400 cattle blood sera from 22 farms in these centers constituted the study material. In the study, commercial ELISA antibody test kit was used to investigate ‘’Mycobacterium avium subsp. Paratuberculosis’’ (MAP) antibodies in cattle blood serum samples. As a result of the analysis, 17 of 400 animals were positive for MAP and prevalence in Ardahan province and its vicinity was determined as 4.25% (17/400). Paratuberculosis was detected in 9 of 22 farms sampled. This result has been predicted that pTB is subclinical in dairy cattle in Ardahan region and may cause economic losses. Considering that this disease is zoonotic, it can be said that public health may also be affected. Therefore, it will be beneficial to carry out more studies on pTB.

Supporting Institution

This study is supported by Kafkas University Scientific Research Projects Coordinator (BAP)

Project Number

project numbered 2017-TS-34

References

  • Abendan N, Sevilla IA, Prieto JM, Garrido JM, Juste RA, Alonso-Hearn M. Mycobacterium aviumsubspeciesparatuberculosis isolates from sheep and goats show reduced persistence in bovine macrophages than cattle,bison, deer and wild boar strains regardless of genotype. Vet Microbiol. 2013; 163:325-334.
  • Alvarez J, De Juan L, Aranaz A. A survey on paratuberculosis in wildlife in Spain. In:8th International Colloquium on Paratuberculosis. Copenhagen, Denmark, 2005.
  • Baumgartner W. ve Khol JL. Paratuberculosıs (Johne´S Disease) in ruminants -an ongoing story, Slov Vet Res. 2006; 43(1):5-10.
  • Civelek T. Paratüberküloz ‘sığırlarda paratüberküloz’. http://www.turancivelek.net/FileUpload/ks117047/File/ptb.pdf. Erişim tarihi: 14.02.2018.
  • Collins M. and Manning E. "Johne's Information Center" The University of Wisconsin-School of Veterinary Medicine, 13 March 2003.
  • Çetinkaya B, Muz A, Ertaş HB, Öngör H, Sezen İY, Gülcü HB. Süt ineklerinde paratüberküloz prevalansının polimeraz zincir reaksiyonu (PZR) ile saptanması. Turk J Vet Anim Sci. 2000; 24:371-379.
  • Florou M, Leontides L, Billinis C. Isolation of Mycobacteium avium subspecies paratuberculosis from non-ruminant wildlife in Greece. In: 8th International Colloquium on Paratuberculosis. Copenhagen, Denmark, 2005.
  • Gilardoni LR, Paolicchi FA, Mundo SL. Bovine paratuberculosis: a review of the advantages and disadvantages of different diagnostic tests. Rev Argent Microbiol. 2012; 44:201-215.
  • Hurley SS, Splitter GA. and Welch RA. Deoxyribonucleic acid relatedness of Mycobacterium paratuberculosis to other members of the family Mycobacteriaceae. Int. J. Syst. Bact. 1988; 38:143-146.
  • Ikiz S, Bagcigil AF, AK S, Ozgur NY, Loaz A. Paratuberculosis in cattle in Turkey detected by PZR. Medycyna Wet. 2005; 61:881-883.
  • Johne HA, Frothingham L. Ein eigenthumlicher fall von tuberculose beim rind (a particular case of tuberculosis in a cow). Deut Z Tiermed Vergl Pathol. 1895; 21:438–454.
  • Jubb TF, Sergeant ES, Callinan AP, Galvin J. Estimate of the sensitivity of an ELISA used to detect johne’s disease in Victorian dairy cattle herds. Aust Vet J. 2004; 82: 569-73.
  • Judge J, Kyriazakis I, Greis A. Clustering of Mycobacterium avium subsp. paratuberculosis in rabbits and the environment: how hot is a hot spot? Appl Environ Microbiol. 2005; 71:6033-6038.
  • Kalis CHJ, Hesselink JW, Barkema HW. Comparison of culture of individual and strastegically pooled bovine faecal samples for Mycobacterium avium subsp. parastuberculosis. In: Manning, E.J.B., Collins, M.T. (Eds). Proceedings of the 6th International Colloquium on Paratuberculosis. Madison. Wisconsin. 1999; 344-8.
  • Lingling L, John PB, Joseph JC, Arlo R, Yrjo TG, Robab K, Megan S, Jessica RB, Vivek K. Identification of sero-reactive antigens for the early diagnosis of Johne's disease in cattle. J. Pone. 2017; 9(1):1-18.
  • Machackova M, Svastova P, Lamka J. Paratuberculosis in farmed and free-living wild ruminants in the Czech Republic. Vet Microbiol. 2004; 101:225-34.
  • Makav M. ve Gökçe E.: Kars yöresi sığırlarında subklinik paratuberkülozun seroprevalansı. Kafkas Univ Vet Fak Derg. 2013; 19(5):913-916.
  • Nielsen SS, Toft N. A review of prevalences of paratuberculosis in farmed animals in Europe. Prev. Vet. Med. 2009; 88:1-14.
  • Öztürk D, Pehlivanoğlu F, Tok AA, Günlü S, Güldalı Y, Turutoğlu H. Seroprevalence of paratuberculosis in the Burdur province (Turkey), in dairy cattle using the enzyme linked immunosorbent assay (ELISA). Israel J Vet Med, 2010; 65:53-57.
  • Selbitz HJ. Bakterielle Krankheiten der Tiere. In: Rolle M, Mayr A, eds. Medizinische Mikrobiologie, Infektions- und Seuchenlehre. 7. Aufl. Enke Verlag, pp 562-3, Stuttgart, 2002.
  • Sivakumar P, Tripathi BN, Singh N. Detection of Mycobacterium avium subsp. paratuberculosis in intestinal and lymph node tissues of water buffaloes (Bubalis bubalois) by PCR and bacterial culture. Vet Microbiol. 2005; 108:263-70.
  • Stricklands J, Scott HM., McJordan, ER. Effects of seasonal climatic conditions on the diagnosis of Mycobacterium avium subspecies paratuberculosis in dairy cattle. J Dairy Sci. 2005; 88: 2432-40.
  • Sweeney RW. Pathogenesis of paratuberculosis, In: Collins, T.M. (Eds) Johne’s Disease. Vet. Clin. Food Anim. 2011; 27:525-535.
  • Thorel MF, Krichevski M and LevyFrebault VV. Numerical taxonomy of mycobactin-dependent mycobacteria, emended description of Mycobacterium avium, and description of Mycobactearium avium subsp. avium subsp. nov., Mycobacterium avium subsp. paratuberculosis subsp. nov and Mycobacterium avium subsp. silvaticum subsp. nov. Int. J. Syst. Bacteriol. 1990; 40:254-260.
  • Vural B, Atala N. Serological study on bovine paratuberculosis in central Anatolia using the microcomplement fixation and tube complement fixation tests. Etlik Vet. Mikrobiol Derg. 1988; 6:87-97.
  • Whittington RJ ve Sergeant ESG. Progress towards understanding the spread, detection and control of Mycobacterium avium subsp paratuberculosis in animal populations, Australian Veterinary Journal. 2001; 79:267-278.
  • William CD and Kun TP. progress towards control of a mycobacterial pathogen, mycobacterium aviumsubsp. paratuberculosis, the causative agent of johne’s disease in cattle and humans. Food Hyg. 2018; 33(4):221-228.
  • Yazıcıoğlu Ö. Paratüberküloz, http://www.bornovavet.gov.tr/paratuberkuloz.htm. Erişim Tarihi: 03.05.2017.
  • Yıldırım D. Civelek T. Prevalence of subclinical paratuberculosis in dairy cattle in Uşak Region. Kafkas Univ Vet Fak Derg. 2013; 19(1):121-126.

Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı

Year 2020, Volume: 13 Issue: 4, 327 - 331, 31.12.2020
https://doi.org/10.30607/kvj.741292

Abstract

Bu çalışmada Ardahan yöresindeki süt sığırlarında paratüberküloz’un (pTB) prevalansının belirlenmesi amaçlandı. Ardahan merkez ve ilçelerinden rastgele seçilen 11 odak ve bu odaklardaki 22 işletmeden alınan toplam 400 sığır kan serumu çalışmanın materyalini oluşturdu. Çalışmada, sığır kan serum örneklerinde ‘’Mycobacterium avium subsp. Paratuberculosis’’ (MAP) antikorlarının araştırılması amacıyla ticari Enzyme Linked Immunosorbent Assay (ELISA) antikor test kiti kullanıldı. Analiz sonucunda 400 hayvandan 17’sinde MAP yönünden pozitiflik belirlendi. Ardahan ili ve çevresindeki yaygınlık oranı %4,25 (17/400) olarak tespit edildi. Örnek alınan toplam 22 çiftliğin 9’unda paratüberküloz’un varlığı tespit edildi. Bu sonuçla, Ardahan yöresindeki süt sığırlarında pTB’un subklinik olarak bulunduğu ve ekonomik kayıplara yol açabileceği öngörülmüştür. Bu hastalığın zoonotik olduğu düşünüldüğünde halk sağlığının da etkilenebileceği söylenebilir. Bu nedenle pTB ile ilgili daha fazla çalışma yapılması faydalı olacaktır.

Project Number

project numbered 2017-TS-34

References

  • Abendan N, Sevilla IA, Prieto JM, Garrido JM, Juste RA, Alonso-Hearn M. Mycobacterium aviumsubspeciesparatuberculosis isolates from sheep and goats show reduced persistence in bovine macrophages than cattle,bison, deer and wild boar strains regardless of genotype. Vet Microbiol. 2013; 163:325-334.
  • Alvarez J, De Juan L, Aranaz A. A survey on paratuberculosis in wildlife in Spain. In:8th International Colloquium on Paratuberculosis. Copenhagen, Denmark, 2005.
  • Baumgartner W. ve Khol JL. Paratuberculosıs (Johne´S Disease) in ruminants -an ongoing story, Slov Vet Res. 2006; 43(1):5-10.
  • Civelek T. Paratüberküloz ‘sığırlarda paratüberküloz’. http://www.turancivelek.net/FileUpload/ks117047/File/ptb.pdf. Erişim tarihi: 14.02.2018.
  • Collins M. and Manning E. "Johne's Information Center" The University of Wisconsin-School of Veterinary Medicine, 13 March 2003.
  • Çetinkaya B, Muz A, Ertaş HB, Öngör H, Sezen İY, Gülcü HB. Süt ineklerinde paratüberküloz prevalansının polimeraz zincir reaksiyonu (PZR) ile saptanması. Turk J Vet Anim Sci. 2000; 24:371-379.
  • Florou M, Leontides L, Billinis C. Isolation of Mycobacteium avium subspecies paratuberculosis from non-ruminant wildlife in Greece. In: 8th International Colloquium on Paratuberculosis. Copenhagen, Denmark, 2005.
  • Gilardoni LR, Paolicchi FA, Mundo SL. Bovine paratuberculosis: a review of the advantages and disadvantages of different diagnostic tests. Rev Argent Microbiol. 2012; 44:201-215.
  • Hurley SS, Splitter GA. and Welch RA. Deoxyribonucleic acid relatedness of Mycobacterium paratuberculosis to other members of the family Mycobacteriaceae. Int. J. Syst. Bact. 1988; 38:143-146.
  • Ikiz S, Bagcigil AF, AK S, Ozgur NY, Loaz A. Paratuberculosis in cattle in Turkey detected by PZR. Medycyna Wet. 2005; 61:881-883.
  • Johne HA, Frothingham L. Ein eigenthumlicher fall von tuberculose beim rind (a particular case of tuberculosis in a cow). Deut Z Tiermed Vergl Pathol. 1895; 21:438–454.
  • Jubb TF, Sergeant ES, Callinan AP, Galvin J. Estimate of the sensitivity of an ELISA used to detect johne’s disease in Victorian dairy cattle herds. Aust Vet J. 2004; 82: 569-73.
  • Judge J, Kyriazakis I, Greis A. Clustering of Mycobacterium avium subsp. paratuberculosis in rabbits and the environment: how hot is a hot spot? Appl Environ Microbiol. 2005; 71:6033-6038.
  • Kalis CHJ, Hesselink JW, Barkema HW. Comparison of culture of individual and strastegically pooled bovine faecal samples for Mycobacterium avium subsp. parastuberculosis. In: Manning, E.J.B., Collins, M.T. (Eds). Proceedings of the 6th International Colloquium on Paratuberculosis. Madison. Wisconsin. 1999; 344-8.
  • Lingling L, John PB, Joseph JC, Arlo R, Yrjo TG, Robab K, Megan S, Jessica RB, Vivek K. Identification of sero-reactive antigens for the early diagnosis of Johne's disease in cattle. J. Pone. 2017; 9(1):1-18.
  • Machackova M, Svastova P, Lamka J. Paratuberculosis in farmed and free-living wild ruminants in the Czech Republic. Vet Microbiol. 2004; 101:225-34.
  • Makav M. ve Gökçe E.: Kars yöresi sığırlarında subklinik paratuberkülozun seroprevalansı. Kafkas Univ Vet Fak Derg. 2013; 19(5):913-916.
  • Nielsen SS, Toft N. A review of prevalences of paratuberculosis in farmed animals in Europe. Prev. Vet. Med. 2009; 88:1-14.
  • Öztürk D, Pehlivanoğlu F, Tok AA, Günlü S, Güldalı Y, Turutoğlu H. Seroprevalence of paratuberculosis in the Burdur province (Turkey), in dairy cattle using the enzyme linked immunosorbent assay (ELISA). Israel J Vet Med, 2010; 65:53-57.
  • Selbitz HJ. Bakterielle Krankheiten der Tiere. In: Rolle M, Mayr A, eds. Medizinische Mikrobiologie, Infektions- und Seuchenlehre. 7. Aufl. Enke Verlag, pp 562-3, Stuttgart, 2002.
  • Sivakumar P, Tripathi BN, Singh N. Detection of Mycobacterium avium subsp. paratuberculosis in intestinal and lymph node tissues of water buffaloes (Bubalis bubalois) by PCR and bacterial culture. Vet Microbiol. 2005; 108:263-70.
  • Stricklands J, Scott HM., McJordan, ER. Effects of seasonal climatic conditions on the diagnosis of Mycobacterium avium subspecies paratuberculosis in dairy cattle. J Dairy Sci. 2005; 88: 2432-40.
  • Sweeney RW. Pathogenesis of paratuberculosis, In: Collins, T.M. (Eds) Johne’s Disease. Vet. Clin. Food Anim. 2011; 27:525-535.
  • Thorel MF, Krichevski M and LevyFrebault VV. Numerical taxonomy of mycobactin-dependent mycobacteria, emended description of Mycobacterium avium, and description of Mycobactearium avium subsp. avium subsp. nov., Mycobacterium avium subsp. paratuberculosis subsp. nov and Mycobacterium avium subsp. silvaticum subsp. nov. Int. J. Syst. Bacteriol. 1990; 40:254-260.
  • Vural B, Atala N. Serological study on bovine paratuberculosis in central Anatolia using the microcomplement fixation and tube complement fixation tests. Etlik Vet. Mikrobiol Derg. 1988; 6:87-97.
  • Whittington RJ ve Sergeant ESG. Progress towards understanding the spread, detection and control of Mycobacterium avium subsp paratuberculosis in animal populations, Australian Veterinary Journal. 2001; 79:267-278.
  • William CD and Kun TP. progress towards control of a mycobacterial pathogen, mycobacterium aviumsubsp. paratuberculosis, the causative agent of johne’s disease in cattle and humans. Food Hyg. 2018; 33(4):221-228.
  • Yazıcıoğlu Ö. Paratüberküloz, http://www.bornovavet.gov.tr/paratuberkuloz.htm. Erişim Tarihi: 03.05.2017.
  • Yıldırım D. Civelek T. Prevalence of subclinical paratuberculosis in dairy cattle in Uşak Region. Kafkas Univ Vet Fak Derg. 2013; 19(1):121-126.
There are 29 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Sciences
Journal Section RESEARCH ARTICLE
Authors

Mesut Karatay 0000-0001-7036-9100

Enes Akyüz 0000-0002-3288-2058

Gürbüz Gökçe 0000-0002-2492-5193

Project Number project numbered 2017-TS-34
Publication Date December 31, 2020
Acceptance Date September 10, 2020
Published in Issue Year 2020 Volume: 13 Issue: 4

Cite

APA Karatay, M., Akyüz, E., & Gökçe, G. (2020). Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı. Kocatepe Veterinary Journal, 13(4), 327-331. https://doi.org/10.30607/kvj.741292
AMA Karatay M, Akyüz E, Gökçe G. Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı. kvj. December 2020;13(4):327-331. doi:10.30607/kvj.741292
Chicago Karatay, Mesut, Enes Akyüz, and Gürbüz Gökçe. “Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı”. Kocatepe Veterinary Journal 13, no. 4 (December 2020): 327-31. https://doi.org/10.30607/kvj.741292.
EndNote Karatay M, Akyüz E, Gökçe G (December 1, 2020) Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı. Kocatepe Veterinary Journal 13 4 327–331.
IEEE M. Karatay, E. Akyüz, and G. Gökçe, “Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı”, kvj, vol. 13, no. 4, pp. 327–331, 2020, doi: 10.30607/kvj.741292.
ISNAD Karatay, Mesut et al. “Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı”. Kocatepe Veterinary Journal 13/4 (December 2020), 327-331. https://doi.org/10.30607/kvj.741292.
JAMA Karatay M, Akyüz E, Gökçe G. Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı. kvj. 2020;13:327–331.
MLA Karatay, Mesut et al. “Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı”. Kocatepe Veterinary Journal, vol. 13, no. 4, 2020, pp. 327-31, doi:10.30607/kvj.741292.
Vancouver Karatay M, Akyüz E, Gökçe G. Ardahan Yöresindeki Sığırlarda Paratüberküloz’un Seroprevalansı. kvj. 2020;13(4):327-31.

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