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Doğum-Sütten Kesim Dönemi Aralığında Besiye Alınan Kuzularda Beslenme Dönemlerinin Oksidatif Stres Düzeyleri Üzerine Etkileri

Year 2022, Volume: 15 Issue: 3, 275 - 284, 30.09.2022
https://doi.org/10.30607/kvj.1054150

Abstract

Bu çalışmada, ırk ve cinsiyete göre homojen seçilmiş 10 kuzudan oluşan 4 deneme grubu ile 40 adet yeni doğan tekiz Akkaraman ve Merinos kuzular kullanılmıştır. Deneme, kuzuların doğumundan itibaren, ilk uygulama 14. günde olmak üzere 21 günlük periyotlar ile 5 besleme periyodunu kapsayan 100 gün sürede gerçekleştirilmiştir. Kuzular ilk iki ay kuzu başlangıç yemi, sonrasında deneme süresince kuzu büyütme yemi ile ad-libitum ve 250g/gün/baş kuru yonca otu ile beslenmişlerdir. Araştırmanın sonunda; en düşük total antioksidan seviye (TAS)’nin Akkaraman erkek kuzularında, en yüksek değerinin ise Merinos ırkı dişi kuzularda olduğu, Merinos ırkı dişilerde de erkeklerine göre daha yüksek bulunduğu tespit edilmiştir (P<0.05). Deneme süresince total oksidan seviye (TOS) ve nativ tiyol (NTL) değerleri bakımından gruplar arasında farklılık olmadığı gözlenmiştir (P˃0.05). Akkaraman ırkı erkek ve dişi kuzulardan elde edilen oksidatif stres indeksi (OSI), Merinos ırkı erkek ve dişi kuzulara ait OSI’nden yüksek bulunmuş, dişi Merinoslarda daha düşük OSI’ne ulaşıldığı (P<0.05), total tiyol (TTL) düzeylerinin Merinos ırkı erkek kuzularda Akkaraman ırkı erkek kuzulara göre arttığı tespit edilmiştir (P <0.05). Merinos ırkının Akkaraman ırkına göre sütten kesim ardından yeme adaptasyonunun daha iyi olduğu sonucuna varılmıştır.

Supporting Institution

Aksaray Üniversitesi Bilimsel Araştırmalar Koordinasyon Birimi

Project Number

2019/030

Thanks

Bu çalışmayı destekleyen Aksaray Üniversitesi Bilimsel Araştırmalar Koordinasyon Birimi'ne teşekkür ederiz.

References

  • Akkuş T. The effect of birth type on total thiol and native thiol in Aleppo goats and kids. J Agric Vet Sci. 2021;14(7): 32-36.
  • Altınçekiç ŞÖ. Stres ve hayvan besleme. Turkiye Klinikleri J Anim Nutr&Nutr Dis. 2016;2(1),61-70.
  • Anonymous. htttps://intweb. tse.org.tr/standard. TS No: TS9610 Hayvan yemleri- metabolik (çevrilebilir) enerji tayini kimyasal metod. 2016; Accessien date: 03.12.1991.
  • AOAC. Official Methods of Analysis (14th ed.). Association of Official Analytical Chemists. Washington, DC. 1984; pp.1112.
  • Ateş İ, Özkayar N, İnan B, Yılmaz FM, Topçuoğlu C, Neşelioğlu S, Erel Ö, Dede F, Yılmaz N. Yeni tanı primer hipertansiyon hastalarında dinamik tiyol/disülfid homeostasisi. 2015; 17. Ulusal Hipertansiyon ve Böbrek Hastalıkları Kongresi, Antalya.
  • Celi P. Biomarkers of oxidative stress in ruminant medicine. Immunopharmacol Immunotoxicol. 2011; 33, 233-240.
  • Cremers CM, Jakob U. Oxidant sensing by reversible disulfide bond formation. The Journal of Biological Chemistry. 2013; 288, 26489-26496.
  • Devasagayam TPA, Tilak JC, Boloor KK. Free radicals and antioxidants in human health: current status and fut ure prospects. J Assoc Physicians India. 2014; 52, 794-804.
  • Duncan DB. Multiple range and multiple f test. Biometrics. 1955;11: 1-42.
  • Düzgüneş O, Kesici T, Gürbüz F. İstatistik Metodları-I. A.Ü. Zir Fak Yay. 861, Ankara. 1983; pp. 299-218.
  • Erel Ö. A new automated colorimetric method for measuring total oxidant status. Clinical Biochemistry. 2005; 38:1103-1111.
  • Erel Ö, Neşelioğlu S. A Novel and automated assay for thiol/disulphide homeostasis. Clinical Biochemistry. 2014; 47:326- 332.
  • Esen F, Yıldız N. Akkaraman, Sakız x Akkaraman melez (F1) kuzularda verim özellikleri II. Besi performansı, kesim ve karkas özellikleri. Turk J Vet Anim Sci. 2000; 24, 215–222 © TÜBİTAK.
  • Garrett K, Beck MR, Marshall CJ, Maxwell TMR, Logan CM, Greer AW, Gregorini P. Varied diets: implications for lamb performance, rumen characteristics, total antioxidant status, and welfare. J Anim Sci. 2021; 99(12): 334-340.
  • George E, Hero L. A precise method for the determination of whole blood and plasma sulfhydryl groups. Anal Biochem. 1979; 93, 98-102.
  • Harma M, Harma M, Erel O. Measurement of the total antioxidant response in preeclampsia with a novel automated method. Eur J Obstet Gyn R B. 2005; 118, 47-51.
  • Heidarpour M, Mohri M, Borji H, Moghaddas E. Oxidant/antioxidant balance and trace elements status in sheep with liver cystic echinococcosis. Comp Clin Pathol. 2013; 22:1043–1049.
  • Huber WW, Parzefall W. Thiols and the chemoprevention of cancer. Current Opinion in Pharmacology. 2007; 7(4): 404-409.
  • Karabulut H, Gülay MŞ. Serbest radikaller. MAKÜ Sag Bil Enst Derg. 2016; 4(1): 50-59.
  • Mercan U. Toksikolojide serbest radikallerin önemi. YYU Vet Fak Derg. 2004;15(1-2): 91-96.
  • Mert H, Yaşar S, Mert N. Investigation of TAS and TOS levels in sheep with hydatid cyst. Eurasian JHS. 2019; 2(4): 164-168.
  • Mialon MM, Boivin X, Durand D, Boissy A, Delval E, Bage AS, Clanet C, Cornilleau F, Parias C, Foury A, Moisan MP, Fassier T, Marcon D, Guilloteau LA, Nowak R. Short- and mid-term effects on performance, health and qualitative behavioural assessment of Romane lambs in different milk feeding conditions. Animal. 2021; 15(3):100157.
  • Mis L, Mert H, Comba A, Comba B, Söğütlü İD, Irak K, Mert N. Some mineral substance, oxidative stress and total antioxidant levels in Norduz and Morkaraman sheep. Van Vet J. 2018; 29 (3): 131-134.
  • Sawal RK, Bhatia DR, Bhasin V, Solanki VK. Effect of dietary levels of protein on pre weaning growth of lambs. Indian Journal of Animal Nutrition. 2011; 13(1):31-34.
  • Sen CK, Packer L. Thiol homeostasis and supplements in physical exercise. The American Journal of Clinical Nutrition. 2000; 72(2): 653-669.
  • Serin İ. Ruminantlarda beslenme, antioksidan sistem ve reprodüksiyon. Turkiye Klinikleri J. Reprod Artif Insemin Special Topics. 2015; 1(3): 48-54.
  • Pratic`o D. Antioxidants and endothelium protection. Atherosclerosis. 2005; 181: 215-224.
  • Tabakoğlu E, Durgut R. Veteriner hekimlikte oksidatif stres ve bazı önemli hastalıklarda oksidatif stresin etkileri. AVKAE. 2013; 3(1): 69-75.
  • TUIK 2020. https://data.tuik.gov.tr/Bulten/Index?p=Hayvansal-Uretim-Istatistikleri-Aralik-2020-37207. Accessien date: 27.02.2021.
  • Turell L, Radic R, Alvarez B. The thiol pool in human plasma: the central contribution of albumin to redox processes. Free Radical Biology and Medicine. 2013; 65: 244-253.
  • Valko M, Izakovic M, Mazur M. Role of oxygen radicals in DNA damage and cancer incidence. Mol Cell Biochem. 2004; 266 (1-2): 37-56.
  • Van Soest PJ. Fiber and physicochemical properties of feeds in: nutritional ecology of the ruminant. Cornell University press. 1994; pp. 140-155.
  • Yokuş B, Çakır DÜ. İn-vivo oksidatif DNA hasarı biyomarkerı 8- hydroxy-2'-deoxyguanosine. Türkiye Klinikleri Journal of Medical Sciences. 2002; 22: 535-543.

The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period

Year 2022, Volume: 15 Issue: 3, 275 - 284, 30.09.2022
https://doi.org/10.30607/kvj.1054150

Abstract

In this study were used 40 newborn singleton Akkaraman and Merino lambs with 4 trial groups consisting of selected 10 lambs homogeneous according to race and gender. Trial was carried out 100 days, covering 5 feeding periods with 21-day periods the first application is on the 14th day from the birth of lambs. The lambs were fed with lamb starter feed for the first two months, then with lamb grower feed ad-libitum and 250 g/day/head dry alfalfa hay. At the end of the study; it was determined that the lowest total antioxidant status (TAS) was in Akkaraman male lambs, the highest was in Merino’s female, and it was found higher in Merino females than males (P<0.05). There was no difference between the groups in terms of total oxidant status (TOS) and native thiol (NTL), during the trial (P˃0.05). Oxidative stress index (OSI) obtained from Akkaraman lambs was found to be higher than Merino, lower OSI was reached in female Merino's, and total thiol (TTL) were increased in Merino male lambs compared to Akkaraman (P<0.05). It was concluded that the Merino had better adaptation to feeding after weaning than the Akkaraman.

Project Number

2019/030

References

  • Akkuş T. The effect of birth type on total thiol and native thiol in Aleppo goats and kids. J Agric Vet Sci. 2021;14(7): 32-36.
  • Altınçekiç ŞÖ. Stres ve hayvan besleme. Turkiye Klinikleri J Anim Nutr&Nutr Dis. 2016;2(1),61-70.
  • Anonymous. htttps://intweb. tse.org.tr/standard. TS No: TS9610 Hayvan yemleri- metabolik (çevrilebilir) enerji tayini kimyasal metod. 2016; Accessien date: 03.12.1991.
  • AOAC. Official Methods of Analysis (14th ed.). Association of Official Analytical Chemists. Washington, DC. 1984; pp.1112.
  • Ateş İ, Özkayar N, İnan B, Yılmaz FM, Topçuoğlu C, Neşelioğlu S, Erel Ö, Dede F, Yılmaz N. Yeni tanı primer hipertansiyon hastalarında dinamik tiyol/disülfid homeostasisi. 2015; 17. Ulusal Hipertansiyon ve Böbrek Hastalıkları Kongresi, Antalya.
  • Celi P. Biomarkers of oxidative stress in ruminant medicine. Immunopharmacol Immunotoxicol. 2011; 33, 233-240.
  • Cremers CM, Jakob U. Oxidant sensing by reversible disulfide bond formation. The Journal of Biological Chemistry. 2013; 288, 26489-26496.
  • Devasagayam TPA, Tilak JC, Boloor KK. Free radicals and antioxidants in human health: current status and fut ure prospects. J Assoc Physicians India. 2014; 52, 794-804.
  • Duncan DB. Multiple range and multiple f test. Biometrics. 1955;11: 1-42.
  • Düzgüneş O, Kesici T, Gürbüz F. İstatistik Metodları-I. A.Ü. Zir Fak Yay. 861, Ankara. 1983; pp. 299-218.
  • Erel Ö. A new automated colorimetric method for measuring total oxidant status. Clinical Biochemistry. 2005; 38:1103-1111.
  • Erel Ö, Neşelioğlu S. A Novel and automated assay for thiol/disulphide homeostasis. Clinical Biochemistry. 2014; 47:326- 332.
  • Esen F, Yıldız N. Akkaraman, Sakız x Akkaraman melez (F1) kuzularda verim özellikleri II. Besi performansı, kesim ve karkas özellikleri. Turk J Vet Anim Sci. 2000; 24, 215–222 © TÜBİTAK.
  • Garrett K, Beck MR, Marshall CJ, Maxwell TMR, Logan CM, Greer AW, Gregorini P. Varied diets: implications for lamb performance, rumen characteristics, total antioxidant status, and welfare. J Anim Sci. 2021; 99(12): 334-340.
  • George E, Hero L. A precise method for the determination of whole blood and plasma sulfhydryl groups. Anal Biochem. 1979; 93, 98-102.
  • Harma M, Harma M, Erel O. Measurement of the total antioxidant response in preeclampsia with a novel automated method. Eur J Obstet Gyn R B. 2005; 118, 47-51.
  • Heidarpour M, Mohri M, Borji H, Moghaddas E. Oxidant/antioxidant balance and trace elements status in sheep with liver cystic echinococcosis. Comp Clin Pathol. 2013; 22:1043–1049.
  • Huber WW, Parzefall W. Thiols and the chemoprevention of cancer. Current Opinion in Pharmacology. 2007; 7(4): 404-409.
  • Karabulut H, Gülay MŞ. Serbest radikaller. MAKÜ Sag Bil Enst Derg. 2016; 4(1): 50-59.
  • Mercan U. Toksikolojide serbest radikallerin önemi. YYU Vet Fak Derg. 2004;15(1-2): 91-96.
  • Mert H, Yaşar S, Mert N. Investigation of TAS and TOS levels in sheep with hydatid cyst. Eurasian JHS. 2019; 2(4): 164-168.
  • Mialon MM, Boivin X, Durand D, Boissy A, Delval E, Bage AS, Clanet C, Cornilleau F, Parias C, Foury A, Moisan MP, Fassier T, Marcon D, Guilloteau LA, Nowak R. Short- and mid-term effects on performance, health and qualitative behavioural assessment of Romane lambs in different milk feeding conditions. Animal. 2021; 15(3):100157.
  • Mis L, Mert H, Comba A, Comba B, Söğütlü İD, Irak K, Mert N. Some mineral substance, oxidative stress and total antioxidant levels in Norduz and Morkaraman sheep. Van Vet J. 2018; 29 (3): 131-134.
  • Sawal RK, Bhatia DR, Bhasin V, Solanki VK. Effect of dietary levels of protein on pre weaning growth of lambs. Indian Journal of Animal Nutrition. 2011; 13(1):31-34.
  • Sen CK, Packer L. Thiol homeostasis and supplements in physical exercise. The American Journal of Clinical Nutrition. 2000; 72(2): 653-669.
  • Serin İ. Ruminantlarda beslenme, antioksidan sistem ve reprodüksiyon. Turkiye Klinikleri J. Reprod Artif Insemin Special Topics. 2015; 1(3): 48-54.
  • Pratic`o D. Antioxidants and endothelium protection. Atherosclerosis. 2005; 181: 215-224.
  • Tabakoğlu E, Durgut R. Veteriner hekimlikte oksidatif stres ve bazı önemli hastalıklarda oksidatif stresin etkileri. AVKAE. 2013; 3(1): 69-75.
  • TUIK 2020. https://data.tuik.gov.tr/Bulten/Index?p=Hayvansal-Uretim-Istatistikleri-Aralik-2020-37207. Accessien date: 27.02.2021.
  • Turell L, Radic R, Alvarez B. The thiol pool in human plasma: the central contribution of albumin to redox processes. Free Radical Biology and Medicine. 2013; 65: 244-253.
  • Valko M, Izakovic M, Mazur M. Role of oxygen radicals in DNA damage and cancer incidence. Mol Cell Biochem. 2004; 266 (1-2): 37-56.
  • Van Soest PJ. Fiber and physicochemical properties of feeds in: nutritional ecology of the ruminant. Cornell University press. 1994; pp. 140-155.
  • Yokuş B, Çakır DÜ. İn-vivo oksidatif DNA hasarı biyomarkerı 8- hydroxy-2'-deoxyguanosine. Türkiye Klinikleri Journal of Medical Sciences. 2002; 22: 535-543.
There are 33 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section RESEARCH ARTICLE
Authors

Duygu Budak 0000-0001-9327-3830

Besime Doğan Daş 0000-0003-2163-2632

Güzin Camkerten 0000-0003-2732-9490

Yavuz Kal 0000-0002-3672-0048

Project Number 2019/030
Publication Date September 30, 2022
Acceptance Date June 15, 2022
Published in Issue Year 2022 Volume: 15 Issue: 3

Cite

APA Budak, D., Doğan Daş, B., Camkerten, G., Kal, Y. (2022). The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period. Kocatepe Veterinary Journal, 15(3), 275-284. https://doi.org/10.30607/kvj.1054150
AMA Budak D, Doğan Daş B, Camkerten G, Kal Y. The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period. kvj. September 2022;15(3):275-284. doi:10.30607/kvj.1054150
Chicago Budak, Duygu, Besime Doğan Daş, Güzin Camkerten, and Yavuz Kal. “The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period”. Kocatepe Veterinary Journal 15, no. 3 (September 2022): 275-84. https://doi.org/10.30607/kvj.1054150.
EndNote Budak D, Doğan Daş B, Camkerten G, Kal Y (September 1, 2022) The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period. Kocatepe Veterinary Journal 15 3 275–284.
IEEE D. Budak, B. Doğan Daş, G. Camkerten, and Y. Kal, “The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period”, kvj, vol. 15, no. 3, pp. 275–284, 2022, doi: 10.30607/kvj.1054150.
ISNAD Budak, Duygu et al. “The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period”. Kocatepe Veterinary Journal 15/3 (September 2022), 275-284. https://doi.org/10.30607/kvj.1054150.
JAMA Budak D, Doğan Daş B, Camkerten G, Kal Y. The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period. kvj. 2022;15:275–284.
MLA Budak, Duygu et al. “The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period”. Kocatepe Veterinary Journal, vol. 15, no. 3, 2022, pp. 275-84, doi:10.30607/kvj.1054150.
Vancouver Budak D, Doğan Daş B, Camkerten G, Kal Y. The Effects of Nutritional Periods on Oxidative Stress Levels in Lambs During Birth-Weaning Period. kvj. 2022;15(3):275-84.

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