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Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri

Year 2022, Volume: 15 Issue: 4, 423 - 431, 31.12.2022
https://doi.org/10.30607/kvj.1134756

Abstract

Bu çalışmada Holştayn ırkı düvelerde yaşamın 9. ayından başlanarak gebeliğin belirlendiği zamana kadar rasyona rumen korumalı lizin ve metiyonin ilavesinin bazı kan metabolizma parametreleri üzerine etkileri incelenmiştir. Bu amaçla 40 adet sağlıklı ve 9 aylık yaşı doldurmuş (9-10 ay arası) Holştayn ırkı düveler rastgele örnekleme metodu ile K (Kontrol) ve U (Uygulama) olmak üzere 2 gruba ayrılmıştır. Kontrol grubundaki düveler NRC (2001)’e göre hazırlanmış standart bir rasyonla, uygulama grubundaki düveler ise rumen korumalı amino asitler kullanılarak (Lysigem ve Methipearl, Kemin Ind., Belgium) lizin (MP’nin %7.1’i) ve metiyonin (MP’in %2.4’ü) düzeyleri artırılmış bir rasyonla ad-libitum olarak beslenmiştir. Tüm düvelerden çalışma başlangıcında, tohumlama zamanında ve gebeliğin tespit edildiği gün vena coccygea yolu ile kan numunesi alınmıştır. Alınan kan numuneleri ilgili kitler kullanılarak glukoz (GLU), betahidroksibütirat (BHBA), esterleşmemiş yağ asitleri (NEFA), total kolesterol (TK), trigliserit (TG), total protein (TP) ve kan üre nitrojeni (BUN) analizleri yapılmıştır. Çalışmada kan metabolizma parametrelerinden GLU, NEFA ve BHBA düzeylerinin prepubertas, tohumlama ve gebelik tespit edilen dönemlerde istatiksel olarak anlamlı şekilde değiştiği (p<0.0001), TK, TP ve BUN düzeylerinin ise anlamlı şekilde değişmediği (p>0.5) tespit edilmiştir. Ayrıca rumen korumalı lizin ve metiyonin kullanılarak rasyonun metabolik lizin ve metiyonin düzeyinin artırılmasının tohumlama zamanında kanda TK seviyesini artırdığı (p<0.005), TP seviyesini ise düşürdüğü belirlenmiştir (p<0.05).

References

  • Anderson, J. L., Kalscheur, K. F., Clapper, J. A., Perry, G. A., Keisler, D. H., Garcia, A. D., & Schingoethe, D. J. (2015). Feeding fat from distillers dried grains with solubles to dairy heifers: II. Effects on metabolic profile. Journal of Dairy Science, 98(8), 5709-5719.
  • Bauman, D. E., and W. B. Currie. 1980. Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis. J. Dairy Sci. 63:1514–1529.
  • Bouyeh, M., & Gevorgyan, O. K. (2011). Influence of excess lysine and methionine on cholesterol, fat and performance of broiler chicks. Journal of Animal and Veterinary Advances, 10(12), 1546-1550.
  • Brickell, J. S., McGowan, M. M., & Wathes, D. C. (2009). Effect of management factors and blood metabolites during the rearing period on growth in dairy heifers on UK farms. Domestic animal endocrinology, 36(2), 67-81.
  • Chelikani PK, Ambrose JD, Keisler DH, Kennelly JJ. (2004) Effect of short-term fasting on plasma concentrations of leptin and other hormones and metabolites in dairy cattle. Domest Anim Endocrinol;26:33–48.
  • Diskin MG and Sreenan JM 2000. Expression and detection of oestrus in cattle. Reproduction Nutrition Development 40, 481–491.
  • Doornenbal, H., Tong, A. K., & Murray, N. L. (1988). Reference values of blood parameters in beef cattle of different ages and stages of lactation. Canadian Journal of Veterinary Research, 52(1), 99.
  • Drackley, J. K., T. R. Overton, and G. N. Douglas. 2001. Adaptations of glucose and long chain fatty acid metabolism in liver of dairy cows during the periparturient period. J. Dairy Sci. 84(E Suppl.):E100–E112.
  • Duffield, T. (2000). Subclinical ketosis in lactating dairy cattle. Veterinary clinics of north america: Food animal practice, 16(2), 231-253.
  • Ettema J. F. and Santos J. E., (2004) Impact of age at calving on lactation, reproduction, health, and income in first-parity Holsteins on commercial farms. J Dairy Sci 2004;87:2730–42.
  • Foldager, J., and K. Sejrsen. (1987). Research in Cattle Production Danish Status and Perspectives. Mammary Gland Development and Milk Production in Dairy Cows in Relation to Feeding and Hormone Manipulation During Rearing. Landhusholdningsselskabets Forlag, Tryk, Denmark.
  • Funston, R. N., J. L. Martin, D. M. Larson, and A. J. Roberts. 2012. Physiology and endocrinology symposium: Nutritional aspects of developing replacement heifers. J. Anim. Sci. 90:1166–1171. Gardner, R. W., J. D. Schum, and L. G. Vargus. (1977). Accelerated growth and early breeding of Holstein heifers. J. Dairy Sci. 60:1941–1948.
  • Giroux, I., Kurowska, E. M., & Carroll, K. K. (1999). Role of dietary lysine, methionine, and arginine in the regulation of hypercholesterolemia in rabbits. The Journal of Nutritional Biochemistry, 10(3), 166-171.
  • Greenwood P, Hunt A, Slepetis R, Finnerty K, Alston C, Beermann D, et al. (2002) Effects of birth weight and postnatal nutrition on neonatal sheep. III. Regulation of energy metabolism. J Anim Sci 2002;80:2850–61.
  • Hossein-Zadeh, N. G.; Ardalan, M., (2011): Estimation of genetic parameters for milk urea nitrogen and its relationship with milk constituents in Iranian Holsteins. Livestock Science 135, 274–281.
  • Hurnik JF, King GJ and Robertson HA 1975. Estrous and related behaviour in postpartum Holstein cows. Applied Animal Ethology 2, 55–68.
  • Keown J. F., Everett R. W. (1986). Effect of days carried calf, days dry, and weight of first calf heifers on yield. J Dairy Sci 1986;69:1891–6.
  • Little, W., and R. M. Kay. (1979). The effects of rapid rearing and early calving on the subsequent performance of dairy heifers. Anim. Prod. 29:131–142
  • National Research Council, Nutrient Requirements of Poultry (9th rev. ed.), National Academy Press, Washington, DC (1994)
  • National Research Council, Nutrient requirements of dairy cattle), National Academy Press, Washington, DC (2001).
  • Ospina, P. A., Nydam, D. V., Stokol, T., & Overton, T. R. (2010). Evaluation of nonesterified fatty acids and β-hydroxybutyrate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseases. Journal of dairy science, 93(2), 546-554.
  • Perry, G. A. 2012. Harnessing basic knowledge of factors controlling puberty to improve synchronization of estrus and fertility in heifers. J. Anim. Sci. 90:1172–1182.
  • Place N. T., Heinrichs A. J., Erb H. N. (1998). The effects of disease, management, and nutrition on average daily gain of dairy heifers from birth to four months. J Dairy Sci 1998;81:1004–9.
  • Reith, S., Pries, M., Verhülsdonk, C., Brandt, H., & Hoy, S. (2014). Influence of estrus on dry matter intake, water intake and BW of dairy cows. Animal, 8(5), 748-753.
  • Roberts, T., Chapinal, N., LeBlanc, S. J., Kelton, D. F., Dubuc, J., & Duffield, T. F. (2012). Metabolic parameters in transition cows as indicators for early-lactation culling risk. Journal of dairy science, 95(6), 3057-3063.
  • Smith JM, Van Amburgh ME, Diaz MC, Lucy MC, Bauman DE. Effect of nutrient intake on the development of the somatotropic axis and its responsiveness to GH in Holstein bull calves. J Anim Sci 2002;80:1528–37.
  • Swali A, Cheng Z, Bourne N,Wathes DC. Metabolic traits affecting growth rates of pre-pubertal calves and their relationship with subsequent survival. Domest Anim Endocrinol 2008;35:300–13.
  • Swanson, E. W. (1960). Effect of rapid growth with fattening of dairy heifers on their lactational ability. J. Dairy Sci. 43: 377–387.
  • Talavera, F., C. S. Park, and G. L. Williams. 1985. Relationships among dietary lipid intake, serum cholesterol and ovarian function in Holstein heifers. J. Anim. Sci. 60:1045–1051
  • Taylor VJ, Beever DE, Bryant MJ, Wathes DC. First lactation ovarian function in dairy heifers in relation to prepubertal metabolic profiles. J Endocrinol 2004;180:63–75.
  • Terré M, Devant M, Bach A. (2006). Performance and nitrogen metabolism of calves fed conventionally or following an enhanced-growth feeding program during the preweaning period. Livestock Sci;105:109–19.
  • Tomlinson, D. L., James, R. E., Bethard, G. L., & McGilliard, M. L. (1997). Influence of undegradability of protein in the diet on intake, daily gain, feed efficiency, and body composition of Holstein heifers. Journal of Dairy Science, 80(5), 943-948.
  • Van Amburgh, M. E., Galton, D. M., Bauman, D. E., Everett, R. W., Fox, D. G., Chase, L. E., & Erb, H. N. (1998). Effects of three prepubertal body growth rates on performance of Holstein heifers during first lactation. Journal of dairy science, 81(2), 527-538.

Effects of Rumen Protected Lysine and Methionine Supplementation on Some Blood Metabolic Parameters in Prepubertal Holstein Heifers

Year 2022, Volume: 15 Issue: 4, 423 - 431, 31.12.2022
https://doi.org/10.30607/kvj.1134756

Abstract

The aim of this study was to investigate the effects of supplemental rumen protected lysine and methionine on some blood metabolic parameters in prepubertal Holstein heifers. Forty, healthy, 9-month-old heifers were divided into two groups as control (C) and treatment (T). C heifers were fed a standard diet which has been prepared according to NRC (2001), whereas T heifers were fed a lysine (7.1% of MP) and methionine (2.4% of MP) enriched (Lysigem and Methipearl, Kemin Ind., Belgium) diet. Blood samples were taken from all heifers at the beginning of the study, on the day of artificial insemination and on the day of pregnancy detection. All blood samples were analyzed for glucose (GLU), beta-hydroxybutyric acid (BHBA), non-esterified fatty acids (NEFA), total cholesterol (TCHOL), triglycerides, total protein (TP) and blood urea nitrogen (BUN). It was determined that the levels of GLU, NEFA and BHBA, which are blood metabolism parameters, changed statistically (p<0.001) in the periods when prepubertal, insemination and pregnancy were detected, while the levels of TKOL, TRIG and BUN did not change significantly. Moreover, increasing lysine and methionine content of the prepubertal diet caused an increase in serum TCHOL concentration (p<0.005) whereas decreased serum TP concentration (p<0.05)

References

  • Anderson, J. L., Kalscheur, K. F., Clapper, J. A., Perry, G. A., Keisler, D. H., Garcia, A. D., & Schingoethe, D. J. (2015). Feeding fat from distillers dried grains with solubles to dairy heifers: II. Effects on metabolic profile. Journal of Dairy Science, 98(8), 5709-5719.
  • Bauman, D. E., and W. B. Currie. 1980. Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis. J. Dairy Sci. 63:1514–1529.
  • Bouyeh, M., & Gevorgyan, O. K. (2011). Influence of excess lysine and methionine on cholesterol, fat and performance of broiler chicks. Journal of Animal and Veterinary Advances, 10(12), 1546-1550.
  • Brickell, J. S., McGowan, M. M., & Wathes, D. C. (2009). Effect of management factors and blood metabolites during the rearing period on growth in dairy heifers on UK farms. Domestic animal endocrinology, 36(2), 67-81.
  • Chelikani PK, Ambrose JD, Keisler DH, Kennelly JJ. (2004) Effect of short-term fasting on plasma concentrations of leptin and other hormones and metabolites in dairy cattle. Domest Anim Endocrinol;26:33–48.
  • Diskin MG and Sreenan JM 2000. Expression and detection of oestrus in cattle. Reproduction Nutrition Development 40, 481–491.
  • Doornenbal, H., Tong, A. K., & Murray, N. L. (1988). Reference values of blood parameters in beef cattle of different ages and stages of lactation. Canadian Journal of Veterinary Research, 52(1), 99.
  • Drackley, J. K., T. R. Overton, and G. N. Douglas. 2001. Adaptations of glucose and long chain fatty acid metabolism in liver of dairy cows during the periparturient period. J. Dairy Sci. 84(E Suppl.):E100–E112.
  • Duffield, T. (2000). Subclinical ketosis in lactating dairy cattle. Veterinary clinics of north america: Food animal practice, 16(2), 231-253.
  • Ettema J. F. and Santos J. E., (2004) Impact of age at calving on lactation, reproduction, health, and income in first-parity Holsteins on commercial farms. J Dairy Sci 2004;87:2730–42.
  • Foldager, J., and K. Sejrsen. (1987). Research in Cattle Production Danish Status and Perspectives. Mammary Gland Development and Milk Production in Dairy Cows in Relation to Feeding and Hormone Manipulation During Rearing. Landhusholdningsselskabets Forlag, Tryk, Denmark.
  • Funston, R. N., J. L. Martin, D. M. Larson, and A. J. Roberts. 2012. Physiology and endocrinology symposium: Nutritional aspects of developing replacement heifers. J. Anim. Sci. 90:1166–1171. Gardner, R. W., J. D. Schum, and L. G. Vargus. (1977). Accelerated growth and early breeding of Holstein heifers. J. Dairy Sci. 60:1941–1948.
  • Giroux, I., Kurowska, E. M., & Carroll, K. K. (1999). Role of dietary lysine, methionine, and arginine in the regulation of hypercholesterolemia in rabbits. The Journal of Nutritional Biochemistry, 10(3), 166-171.
  • Greenwood P, Hunt A, Slepetis R, Finnerty K, Alston C, Beermann D, et al. (2002) Effects of birth weight and postnatal nutrition on neonatal sheep. III. Regulation of energy metabolism. J Anim Sci 2002;80:2850–61.
  • Hossein-Zadeh, N. G.; Ardalan, M., (2011): Estimation of genetic parameters for milk urea nitrogen and its relationship with milk constituents in Iranian Holsteins. Livestock Science 135, 274–281.
  • Hurnik JF, King GJ and Robertson HA 1975. Estrous and related behaviour in postpartum Holstein cows. Applied Animal Ethology 2, 55–68.
  • Keown J. F., Everett R. W. (1986). Effect of days carried calf, days dry, and weight of first calf heifers on yield. J Dairy Sci 1986;69:1891–6.
  • Little, W., and R. M. Kay. (1979). The effects of rapid rearing and early calving on the subsequent performance of dairy heifers. Anim. Prod. 29:131–142
  • National Research Council, Nutrient Requirements of Poultry (9th rev. ed.), National Academy Press, Washington, DC (1994)
  • National Research Council, Nutrient requirements of dairy cattle), National Academy Press, Washington, DC (2001).
  • Ospina, P. A., Nydam, D. V., Stokol, T., & Overton, T. R. (2010). Evaluation of nonesterified fatty acids and β-hydroxybutyrate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseases. Journal of dairy science, 93(2), 546-554.
  • Perry, G. A. 2012. Harnessing basic knowledge of factors controlling puberty to improve synchronization of estrus and fertility in heifers. J. Anim. Sci. 90:1172–1182.
  • Place N. T., Heinrichs A. J., Erb H. N. (1998). The effects of disease, management, and nutrition on average daily gain of dairy heifers from birth to four months. J Dairy Sci 1998;81:1004–9.
  • Reith, S., Pries, M., Verhülsdonk, C., Brandt, H., & Hoy, S. (2014). Influence of estrus on dry matter intake, water intake and BW of dairy cows. Animal, 8(5), 748-753.
  • Roberts, T., Chapinal, N., LeBlanc, S. J., Kelton, D. F., Dubuc, J., & Duffield, T. F. (2012). Metabolic parameters in transition cows as indicators for early-lactation culling risk. Journal of dairy science, 95(6), 3057-3063.
  • Smith JM, Van Amburgh ME, Diaz MC, Lucy MC, Bauman DE. Effect of nutrient intake on the development of the somatotropic axis and its responsiveness to GH in Holstein bull calves. J Anim Sci 2002;80:1528–37.
  • Swali A, Cheng Z, Bourne N,Wathes DC. Metabolic traits affecting growth rates of pre-pubertal calves and their relationship with subsequent survival. Domest Anim Endocrinol 2008;35:300–13.
  • Swanson, E. W. (1960). Effect of rapid growth with fattening of dairy heifers on their lactational ability. J. Dairy Sci. 43: 377–387.
  • Talavera, F., C. S. Park, and G. L. Williams. 1985. Relationships among dietary lipid intake, serum cholesterol and ovarian function in Holstein heifers. J. Anim. Sci. 60:1045–1051
  • Taylor VJ, Beever DE, Bryant MJ, Wathes DC. First lactation ovarian function in dairy heifers in relation to prepubertal metabolic profiles. J Endocrinol 2004;180:63–75.
  • Terré M, Devant M, Bach A. (2006). Performance and nitrogen metabolism of calves fed conventionally or following an enhanced-growth feeding program during the preweaning period. Livestock Sci;105:109–19.
  • Tomlinson, D. L., James, R. E., Bethard, G. L., & McGilliard, M. L. (1997). Influence of undegradability of protein in the diet on intake, daily gain, feed efficiency, and body composition of Holstein heifers. Journal of Dairy Science, 80(5), 943-948.
  • Van Amburgh, M. E., Galton, D. M., Bauman, D. E., Everett, R. W., Fox, D. G., Chase, L. E., & Erb, H. N. (1998). Effects of three prepubertal body growth rates on performance of Holstein heifers during first lactation. Journal of dairy science, 81(2), 527-538.
There are 33 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Surgery
Journal Section RESEARCH ARTICLE
Authors

Oğuzhan Sarıibrahimoğlu 0000-0002-1928-6892

Hande Işıl Akbağ 0000-0002-7325-4453

Cangir Uyarlar 0000-0002-7803-2454

Early Pub Date December 12, 2022
Publication Date December 31, 2022
Acceptance Date November 24, 2022
Published in Issue Year 2022 Volume: 15 Issue: 4

Cite

APA Sarıibrahimoğlu, O., Akbağ, H. I., & Uyarlar, C. (2022). Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri. Kocatepe Veterinary Journal, 15(4), 423-431. https://doi.org/10.30607/kvj.1134756
AMA Sarıibrahimoğlu O, Akbağ HI, Uyarlar C. Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri. kvj. December 2022;15(4):423-431. doi:10.30607/kvj.1134756
Chicago Sarıibrahimoğlu, Oğuzhan, Hande Işıl Akbağ, and Cangir Uyarlar. “Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri”. Kocatepe Veterinary Journal 15, no. 4 (December 2022): 423-31. https://doi.org/10.30607/kvj.1134756.
EndNote Sarıibrahimoğlu O, Akbağ HI, Uyarlar C (December 1, 2022) Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri. Kocatepe Veterinary Journal 15 4 423–431.
IEEE O. Sarıibrahimoğlu, H. I. Akbağ, and C. Uyarlar, “Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri”, kvj, vol. 15, no. 4, pp. 423–431, 2022, doi: 10.30607/kvj.1134756.
ISNAD Sarıibrahimoğlu, Oğuzhan et al. “Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri”. Kocatepe Veterinary Journal 15/4 (December 2022), 423-431. https://doi.org/10.30607/kvj.1134756.
JAMA Sarıibrahimoğlu O, Akbağ HI, Uyarlar C. Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri. kvj. 2022;15:423–431.
MLA Sarıibrahimoğlu, Oğuzhan et al. “Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri”. Kocatepe Veterinary Journal, vol. 15, no. 4, 2022, pp. 423-31, doi:10.30607/kvj.1134756.
Vancouver Sarıibrahimoğlu O, Akbağ HI, Uyarlar C. Holştayn Irkı Düvelerde Pubertas Öncesinde Rasyona Rumen Korumalı Lizin Ve Metiyonin İlavesinin Bazı Kan Metabolizma Parametreleri Üzerine Etkileri. kvj. 2022;15(4):423-31.

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