Abstract
Trazodone is an antidepressent drug and it isn’t get involved in other antidepressent drug such as tricyclic, tetracyclic agent. Trazodone is suggested to some event of insomnia–associated with antidepressent. . When trazodone is taken over dose, cardiac side effect as conduction block, myocardial infarction, life-threatining arrythmia, bradycardia, hipotension and cardiac arrest can seem. Cardiac side effethis events are uncomman and thae ocur dose-dependent. The patient who was taken trazodone ,brought to emergency room following syncope by ambulance service. She has taken first dose of trazodone at last night. Sinüs bradycardia has established on her ECG and she hasn’t any risk factor for bradycardia. In this case we aim of present a patient who had syncope that was induced by trazodone
References
- Reference1 Soldatos C.R., Allaert F.A., Ohta T., et al: How do individuals sleep around the world? Results from a single-day survey in ten countries. Sleep Med 2005; 6: pp. 5-13 Reference2 Mendelson W.B.: A review of the evidence for the efficacy and safety of trazodone in insomnia. J Clin Psychiatry 2005; 66: pp. 469-476 Reference3 Wilson S.J., Nutt D.J., Alford C., et al: British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. J Psychopharmacol 2010; 24: pp. 1577-1601 reference4 Institute of Medicine : Sleep disorders and sleep deprivation: an unmet public health problem. Washington DC. Reference5 Thompson C.: Onset of action of antidepressants: results of different analyses. Hum Psychopharmacol 2002; 17: pp. S27-S32 reference6 Wichniak A., Wierzbicka A., Walecka M., et al: Effects of antidepressants on sleep. Curr Psychiatry Rep 2017; 19: pp. 63 Reference7 Bossini L., Casolaro I., Koukouna D., et al: Off-label uses of trazodone: a review. Expert Opin Pharmacother 2012; 13: pp. 1707-1717 Reference8 Stahl S.M.: Mechanism of action of trazodone: a multifunctional drug. CNS Spectr 2009; 14: pp. 536-546
Abstract
Trazodone is an antidepressent drug and it isn’t get involved in other antidepressent drug such as tricyclic, tetracyclic agent. Trazodone is suggested to some event of insomnia–associated with antidepressent. . When trazodone is taken over dose, cardiac side effect as conduction block, myocardial infarction, life-threatining arrythmia, bradycardia, hipotension and cardiac arrest can seem. Cardiac side effethis events are uncomman and thae ocur dose-dependent. The patient who was taken trazodone ,brought to emergency room following syncope by ambulance service. She has taken first dose of trazodone at last night. Sinüs bradycardia has established on her ECG and she hasn’t any risk factor for bradycardia. In this case we aim of present a patient who had syncope that was induced by trazodone
References
- Reference1 Soldatos C.R., Allaert F.A., Ohta T., et al: How do individuals sleep around the world? Results from a single-day survey in ten countries. Sleep Med 2005; 6: pp. 5-13 Reference2 Mendelson W.B.: A review of the evidence for the efficacy and safety of trazodone in insomnia. J Clin Psychiatry 2005; 66: pp. 469-476 Reference3 Wilson S.J., Nutt D.J., Alford C., et al: British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. J Psychopharmacol 2010; 24: pp. 1577-1601 reference4 Institute of Medicine : Sleep disorders and sleep deprivation: an unmet public health problem. Washington DC. Reference5 Thompson C.: Onset of action of antidepressants: results of different analyses. Hum Psychopharmacol 2002; 17: pp. S27-S32 reference6 Wichniak A., Wierzbicka A., Walecka M., et al: Effects of antidepressants on sleep. Curr Psychiatry Rep 2017; 19: pp. 63 Reference7 Bossini L., Casolaro I., Koukouna D., et al: Off-label uses of trazodone: a review. Expert Opin Pharmacother 2012; 13: pp. 1707-1717 Reference8 Stahl S.M.: Mechanism of action of trazodone: a multifunctional drug. CNS Spectr 2009; 14: pp. 536-546
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Case Report |
| Authors | |
| Publication Date | April 30, 2020 |
| Submission Date | December 22, 2019 |
| Published in Issue | Year 2020 |