Signet-Ring Cell Adenocarcinoma Of Urinary Bladder Having Primary Gastric Origine: Case Report

Year 2018, Volume: 10 Issue: 1, 42 - 44, 01.04.2018

Oğuzhan Parlakkılıç Egemen Avcı Fatih Kurtuluş Orhun Sinanoğlu

https://doi.org/10.1155/2015/127516

Abstract

Primary bladder tumor is a frequent urological malignancy, whereas the incidence of metastatic bladder tumor from a distant organ is quite rare. Metastatic bladder tumors are responsible for less than 2 % of all bladder tumors and originate most commonly from a melanoma, breast cancer, and gastric cancer. Signet ring cell cancer is a rare type of bladder malignancy, accounting for approximately 0,24% of all urinary bladder malignancy. We report a case of a 68 years-old woman who underwent total gastrectomy and left pneumonectomy 2 years ago. On routine control, thickening of bladder wall with bilateral grade 1-2 hydronephrosis was detected on ultrasonography and computerized tomography scan. A bladder tumor was detected and resected with transuretral resection. The histopathological examination revealed secondary Signet ring cell adenocarcinoma of the urinary bladder.

Keywords

Signet ring cell adenocarcinoma, bladder tumor, stomach carcinoma

Gastrik Primeri Olan Mesane Yüzük Hücreli Adenokarsinom: Olgu Sunumu

Abstract

Primer mesane tümörleri sık görülen ürolojik kanserlerdir. Uzak bir organ kaynaklı metastatik mesane tümörleri ise oldukça nadirdir. Metastatik mesane tümörleri tüm mesane tümörlerinin % 2’sinden az görülür ve genellikle melanom, meme kanseri, gastrik kanser kaynaklıdır. Yüzük hücreli mesane kanseri oldukça nadir görülür ve tüm mesane kanserlerinin yaklaşık % 2,4’ünü oluşturur. Biz bu yazımızda 2 yıl önce primer mide kanseri nedeniyle total gastrektomi ve sol pnömonektomi operasyonları geçiren 68 yaşındaki bir hastayı sunduk. Hastamızda, rutin kontroller sırasında, ultrasonografi ve Bilgisayarlı Tomografi BT tetkiklerinde bilateral grade 1-2 hidronefroz ile birlikte mesane duvar kalınlaşması tespit edildi. Mesane tümörü tespit edilip transüretral rezeksiyon yapıldı. Histopatolojik değerlendirme sonucu yüzük hücreli mesane adenokarsinomu geldi.

Keywords

Yüzük hücreli adenokarsinom, mesane tümörü, mide karsinomu

References

• 1. Kerem Okutur, Orhan Ender Eren, Gokhan Demir. Metastasis of Gastric Signet-Ring Cell Carcinoma to the Urinary Bladder: A case report and Review of the literature. Case reports in Oncological Medicine, 2015 Article ID 127516 http://dx.doi. org/10.1155/2015/127516
• 2. J. Michels, S.Barbour, D. Cavers and K.N. Chi.’ Metastatic signet ring cell cancer of the bladder responding to chemotherapy with capacitabine: case report and review of the literature. Can Urol Assoc J. 2010; 4(2): 55–57
• 3. W.Song, S.J, Wu, Y.L.He et al. ‘ Clinicopathological features and survival of patients with colorectal mucinous, signet-ring cell or non mucinous adenocarcinoma Chinese Medical Journal, 2009;1(3): 122-125
• 4. J Singh, V. Zherebitskiy, D.Grynspan, PM Czaykowski Metastatic signet ring cell adenocarcinoma of the bladder: responsive to treatment Journal of Canadian Urological Association 2012; 6: 15-19
• 5. Wagner AD, Grothe W, Haerting J, Kleber G, Grothey A, Fleig WE. Chemotherapy in advanced gastric cancer: A systemic review and meta-analysis based on aggregate data J Clin Oncol. 2006; 24:2093-2099
• 6. Van Cutsem E, Mosieyenko VM, Tjulandin S, et al V325 Study Group. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group. J Clin Oncol. 2006;1;24(31):4991-4997.
• 7. Bang YJ, Van Cutsem E, Feyereislova A, et al. ToGA Trial Investigators. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastrooesophageal junction cancer (ToGA): a phase 3, openlabel, randomised controlled trial. Lancet. 2010 Aug 28;376(9742):687-697.