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A Case of Systemic Lupus Erythematosus Presenting with High Serum Ca 125 Level

Year 2016, Volume: 8 Issue: 2, 1 - 3, 01.08.2016

Abstract

Objectives: A 31 years old woman who has had pain of knee, wrist, ankle from time to time for 2 years together with high fever and night sweating for the last 6 months presented to hospital. Her radiological examinations were revealed bilateral pleural fluid, pericardial effusion and ascites. Pancytopenia and proteinuria were present. Based on clinical, laboratory and serological findings, the patient was diagnosed SLE. The level of serum Ca 125 was measured 192 U/I. Clinical improvement with steroid treatment was achieved. Control of serum Ca 125 level was found 18 U/L.

References

  • Kılıç L, Aykan F. Onkoloji ve tümör belirteçleri. Klinik Gelişim 2011; 24: 1-3.
  • Daoud E, Bodor G. Ca-125 concentrations in malignant and nonmalignant disease. Clin Chem 1991; 37: 1968-1974.
  • Yilmaz A, Ece F, Bayramgurler B, Akkaya E, Baran R. The value of Ca 125 in the evaluation of tuberculosis activity. Respir Med 2001; 95: 666-669.
  • Yang Z, Liang Y, Zhong Y. Serum Ca125 eleva- tion is independently associated with serositis in SLE patients. Clin Exp Rheumatol 2012; 30: 93-98.
  • Moncayo R, Moncayo H. Serum levels of CA 125 are elevated in patients with active systemic lupus erythematosus. Obstet Gynecol. 1991; 77:932-934.
  • Tan NS, Hwang SW. Severe edema and elevated CA 125 in a 56-year-old woman. CMAJ 2012; 184: 671-673.
  • Iacconi C, Bulleri A, Tavoni A, ıacconi P, Bom- bardieri S, Caramella D. Patient with Systemic Lupus Erythematosus (SLE), complex adnexal masses and ascites. Volume 4, Number 2.
  • Petri M, Orbai AM, Alarcon GS et al. Derivation and validation of the Systemic Lupus Interna- tional Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum 2012; 64: 2677-2686.
  • Şen NS, Yılmaz A, Akkaya E, Bayramgürler B, Akçiçek F, Baran R. Tüberküloz plörezinin değer- lendirilmesinde Ca 125’in değeri. Akciğer Arşivi 2001; 2: 59-63.
  • Öcal PA, Akşahin A, Çetin T, Yıldırım İS. Cancer antijen 125 levels in patients with ascites. Turk J Gastroenterol 2003; 14: 257-261

Yüksek Serum Ca 125 Düzeyi ile Seyreden Sistemik Lupus Eritematozis Olgusu

Year 2016, Volume: 8 Issue: 2, 1 - 3, 01.08.2016

Abstract

Amaç: Otuz bir yaşında, kadın hasta 2 yıldır zaman zaman olan diz, el bileği ve ayak bileğinde ağrı son 6 ayda buna eklenen gece terlemesi ve ateş yüksekliği yakınmaları ile hastaneye başvurdu. Radyolojik incelemelerinde bilateral plevral sıvı, perikardiyal sıvı ve asit saptandı. Hastada pansitopeni ve proteinüri mevcuttu. Hastaya klinik, laboratuvar ve serolojik bulgulara dayanılarak Sistemik Lupus Eritematozis tanısı konuldu. Serum Ca 125 düzeyi 192 U/L olarak ölçüldü. Steroid tedavi ile klinik düzelme sağlandı. Kontrolünde serum Ca 125 düzeyi 18 U/L olarak bulundu.

References

  • Kılıç L, Aykan F. Onkoloji ve tümör belirteçleri. Klinik Gelişim 2011; 24: 1-3.
  • Daoud E, Bodor G. Ca-125 concentrations in malignant and nonmalignant disease. Clin Chem 1991; 37: 1968-1974.
  • Yilmaz A, Ece F, Bayramgurler B, Akkaya E, Baran R. The value of Ca 125 in the evaluation of tuberculosis activity. Respir Med 2001; 95: 666-669.
  • Yang Z, Liang Y, Zhong Y. Serum Ca125 eleva- tion is independently associated with serositis in SLE patients. Clin Exp Rheumatol 2012; 30: 93-98.
  • Moncayo R, Moncayo H. Serum levels of CA 125 are elevated in patients with active systemic lupus erythematosus. Obstet Gynecol. 1991; 77:932-934.
  • Tan NS, Hwang SW. Severe edema and elevated CA 125 in a 56-year-old woman. CMAJ 2012; 184: 671-673.
  • Iacconi C, Bulleri A, Tavoni A, ıacconi P, Bom- bardieri S, Caramella D. Patient with Systemic Lupus Erythematosus (SLE), complex adnexal masses and ascites. Volume 4, Number 2.
  • Petri M, Orbai AM, Alarcon GS et al. Derivation and validation of the Systemic Lupus Interna- tional Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum 2012; 64: 2677-2686.
  • Şen NS, Yılmaz A, Akkaya E, Bayramgürler B, Akçiçek F, Baran R. Tüberküloz plörezinin değer- lendirilmesinde Ca 125’in değeri. Akciğer Arşivi 2001; 2: 59-63.
  • Öcal PA, Akşahin A, Çetin T, Yıldırım İS. Cancer antijen 125 levels in patients with ascites. Turk J Gastroenterol 2003; 14: 257-261
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Arzu Cennet Işık This is me

Musa Temel This is me

Esra Ataoğlu This is me

Mesut Ayer This is me

Gülbanu Horzum Ekinci This is me

Publication Date August 1, 2016
Published in Issue Year 2016 Volume: 8 Issue: 2

Cite

Vancouver Işık AC, Temel M, Ataoğlu E, Ayer M, Horzum Ekinci G. Yüksek Serum Ca 125 Düzeyi ile Seyreden Sistemik Lupus Eritematozis Olgusu. Maltepe tıp derg. 2016;8(2):1-3.