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Rocuronium-induced allergic reaction during anesthesia induction in open heart surgery

Year 2014, Volume: 6 Issue: 3, 1 - 2, 01.12.2014

Abstract

In this article, we present a case of allergic reaction due to rocuronium during induction of anesthesia for coronary bypass surgery. Widespread erythematous and bullous eruptions occurred on the skin of the patient immediately after induction of anesthesia following application of rocuronium, propofol and fentanyl, respectively. The patient was intubated and mechanical ventilation was started immediately. The patient's hemodynamic parameters and peripheral oxygen saturation values did not change. IV corticosteroid administered to the patient. The operation was continued. Follow-up and treatment was continued in the ICU intensive care unit .In conclusion, successful cardiopulmonary resuscitation and intensive care is very important against allergic reactions induced by rocuronium

References

  • Heier T, Guttormsen A. Anaphylactic reactions during induction of anaesthesia using rocuro- nium for muscle relaxation: a report including 3 cases. Acta Anaesthesiol Scand 2000; 44: 775-781.
  • Mertes P, Aimone-Gastin I, Guéant-Rodriguez R, et al. Hypersensitivity reactions to neuro- muscular blocking agents. Curr Pharm Des 2008; 14: 2809-2825.
  • Matthey P, Wang P, Finegan BA, Donnelly M. Rocuronium anaphylaxis and multiple neu- romuscular blocking drug sensitivities. Can J Anaesth 2000; 47: 890-893.
  • Mertes PM, Laxenaire MC, Alla F, des Réactions Anaphylactoïdes GE. Anaphylactic and ana- phylactoid reactions occurring during anes- thesia in France in 1999–2000. Anesthesiology 2003; 99: 536.
  • Martyn JJA, Standaert FG: Neuromuscular physiology and pharmacology, In: Miller RD, Eriksson LI, Fleisher LA: Miller’s Anesthesia. 5th edition, Churchill Livings-tone, New York, USA 2000: 735-751.
  • Galletly D, Treuren B. Anaphylactoid reactions during anaesthesia. Anaesthesia 1985; 40: 329-333.

Açık kalp ameliyatında anestezi indüksiyonu sırasında roküronyum'a bağlı gelişen alerjik reaksiyon

Year 2014, Volume: 6 Issue: 3, 1 - 2, 01.12.2014

Abstract

Bu makalede; koroner bypass ameliyatı planlanan, anestezi indüksiyonu sırasında roküronyum'a bağlı alerjik reaksiyon gelişen olguyu ve tedavisini sunmayı amaçladık.Anestezi indüksiyonunda sırasıyla propofol, rokuronyum ve fentanil uygulamasının hemen ardından hastanın cildinde yaygın erimatöz ve büllöz döküntüler gelişti. Hasta hemen entübe edilerek mekanik ventilasyona başlandı. Hastanın hemodinamik paremetrelerinde ve periferik satürasyon değerinde bir değişiklik olmadı. Hastaya iv. olarak kortikosteroid yapıldı. Operasyona devam edildi. YBÜ'de takip ve tedavisine devam edildi.Sonuç olarak rokuronyum'a bağlı olarak gelişen alerjik reaksiyonlarda başarılı kardiyopulmoner resüsitasyon ve yoğun bakım takibinin çok önemli olduğu kanısındayız.

References

  • Heier T, Guttormsen A. Anaphylactic reactions during induction of anaesthesia using rocuro- nium for muscle relaxation: a report including 3 cases. Acta Anaesthesiol Scand 2000; 44: 775-781.
  • Mertes P, Aimone-Gastin I, Guéant-Rodriguez R, et al. Hypersensitivity reactions to neuro- muscular blocking agents. Curr Pharm Des 2008; 14: 2809-2825.
  • Matthey P, Wang P, Finegan BA, Donnelly M. Rocuronium anaphylaxis and multiple neu- romuscular blocking drug sensitivities. Can J Anaesth 2000; 47: 890-893.
  • Mertes PM, Laxenaire MC, Alla F, des Réactions Anaphylactoïdes GE. Anaphylactic and ana- phylactoid reactions occurring during anes- thesia in France in 1999–2000. Anesthesiology 2003; 99: 536.
  • Martyn JJA, Standaert FG: Neuromuscular physiology and pharmacology, In: Miller RD, Eriksson LI, Fleisher LA: Miller’s Anesthesia. 5th edition, Churchill Livings-tone, New York, USA 2000: 735-751.
  • Galletly D, Treuren B. Anaphylactoid reactions during anaesthesia. Anaesthesia 1985; 40: 329-333.
There are 6 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Tülay Örki This is me

Halide Oğuş This is me

Rezzan Yaltırık This is me

Atakan Erkılınç This is me

Deniz Avan This is me

Yücel Özen This is me

Tuncer Koçak This is me

Davut Çekmecelioğlu This is me

Publication Date December 1, 2014
Published in Issue Year 2014 Volume: 6 Issue: 3

Cite

Vancouver Örki T, Oğuş H, Yaltırık R, Erkılınç A, Avan D, Özen Y, Koçak T, Çekmecelioğlu D. Açık kalp ameliyatında anestezi indüksiyonu sırasında roküronyum’a bağlı gelişen alerjik reaksiyon. Maltepe tıp derg. 2014;6(3):1-2.