Surgical verification and false positivity in sarcoma

Year 2013, Volume: 5 Issue: 2, 38 - 41, 01.08.2013

Uğur Temel Aslı Gül Akgül Mustafa Faik Seçkin

Abstract

Surgical resection of pulmonary metastases is now considered a standard therapeutic procedure in properly selected cases and is routinely performed in many departments of thoracic surgery. Complete surgical excision of all pulmonary deposits is often technically feasible with low morbidity and mortality. It is widely accepted that surgical resection is the first-line therapy for isolated pulmonary metastases if the primary site of tumor is under control. Lung metastases are found in up to 30% of patients with osteosarcoma. Survival rates up to 45% are possible in interdisciplinary concepts with aggressive surgical approach and chemotherapy. Pulmonary metastasectomy is mandatory for long-term survival in patients with pulmonary metastases in osteosarcoma. This depends usually on complete surgical resection which is the main prognostic factor for survival, more than the metastatic stage. Herein we report a case of osteogenic sarcoma, operated because of a lung tumor diagnosed as malignant at PET-CT and tranthoracic biopsy in whom the final diagnosis was not metastasis, was a benign lung pathology.

Keywords

sarcoma, false positive imaging, surgery

Sarkomda cerrahi doğrulama ve yalancı pozitiflik

Abstract

Akciğer metastazlarında cerrahi rezeksiyon günümüzde standart tedavi yöntemi olarak kabul görmekte ve pek çok göğüs cerrahisi kliniğince rutin şekilde uygulanmaktadır. Komplet cerrahi eksizyon düşük mortalite ve morbidite ile sıklıkla teknik olarak uygun olmaktadır ve eğer primer tümör kontrol altında ise ilk basamak tedavi olarak kabul edilmektedir. Osteosarkomda akciğer metastazı yaklaşık %30 oranında gözlenmektedir. Agresif cerrahi yaklaşım ve kemoterapiyi içeren tedavi disiplinleri ile sağ kalım %45'lere kadar çıkabilmektedir. Akciğer metastazı olan osteosarkom vakalarında uzun dönem sağ kalım için metastatik evreden çok komplet cerrahi önem taşımaktadır. Burada osteosarkom tanılı, takiplerinde akciğer lezyonu tespit edilen ve PET-BT ile transtorasik biyopsi sonucu maligniteyi işaret eden, rezeksiyon sonrası patolojisi ise benign olarak öğrenilen vakamızı sunduk.

Keywords

sarkom, yanlış pozitif görüntüleme, cerrahi

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