New isolates of Streptomyces from Issyk-Kul region soils for biopharmacology.

Year 2010, Volume: 2 Issue: 11, 0 - 0, 01.01.2010

T.d Doolotkeldieva C. T. Bobusheva M. W. Konurbaeva

Abstract

3889 colony forming units of actynomyces have been screened through E.coli cultures containing the resistant to known antibiotics plasmids used in medical practice. 54 isolates of Streptomyces producing potentially new antibiotic compounds have been screened. New PKS genes in soils of Issuk-Kul region have been found as a result of molecular screening by polyketide synthetase primers. The cosmid libraries of PKS genes have been created from soils sampled from Issuk-Kul region

Keywords

soil, Streptomyces isolates, screening for antibiotic substances, PCR analysis, PKS genes

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