Zehirli Mantarların Potansiyel Kardiyojenik Etkileri

Abstract

İnsanlık tarihinin her aşamasında doğal kaynaklar insaların kurtarıcısı olmuştur. Mantarlar özellikle yagmur mevsimlerinde yoğun olarak bulunan oldukça değerli gıda kaynaklarıdır. Mantarlar beslenme durumlarına göre zehirli, yenir veya yenmez olarak gruplandırılabilir. Bu grupların olumlu veya olumsuz etkileri vardır. Bazı mantar türleri yapılarındaki biyoaktif bileşikler sayesinde farklı tıbbi özelliklere sahiptir. Özellikle insan tüketimi için mantar türlerini kullanmadan önce, bazı yenilebilir türlerde bile toksik maddeler tanımlandığı için toksikolojik profillerini karakterize etmek gerekir. Mantar zehirlenmesi (MP) olarak bilinen mycetism, uluslararası bir sağlık sorunudur. Mantarlar içerisnde ölümcül zehirlenmelere neden olanlar ve zehirlenme semptomları sınırlı olanlar vardır. Zehirli mantarlar türlerine veya neden oldukları semptomlara göre sitotoksik, nörotoksik, miyotoksik, gastroirritan mantarlar olarak birçok sınıfa ayrılır. Mantar zehirlenmesinin karaciğer, böbrekler ve merkezi sinir sistemi üzerinde ciddi toksisiteye neden olabileceği bilinmektedir. Ancak bunun kalp fonksiyonları üzerindeki etkisi henüz belirlenmemiştir. Yapılan bu araştırmada zehirli mantarlar ve görülen kardiyolojik etkileri üzerinde durulmuştur.

Keywords

• Kardiyojenik etkiler
• zehirli mantarlar
• sendromlar
• yabani mantar

Potential Cardiogenic Effects of Poisonous Mushrooms

Abstract

Natural resources have been the savior of people at every stage of human history. Mushrooms are very valuable food sources, especially in the rainy seasons. They can be grouped as poisonous, edible or inedible, depending on their nutritional status. These groups have positive or negative effects. Some types of mushrooms have different medicinal properties thanks to their bioactive compounds. It is necessary to characterize their toxicological profiles, especially before using mushroom species for human consumption, as toxic substances are identified even in some edible species. Mycetism, known as mushroom poisoning, is an international health problem. There are those that cause deadly poisoning and limited symptoms of poisoning in mushrooms. Poisonous mushrooms are divided into many classes as cytotoxic, neurotoxic, myotoxic, gastroirritan mushrooms according to their types or symptoms they cause. It is known that mushroom poisoning can cause serious toxicity on the liver, kidneys and central nervous system. However, its effect on heart function has not been determined yet. This study focused on poisonous mushrooms and their cardiological effects.

Keywords

• Cardiogenic effects
• poisonous mushrooms
• syndromes
• wild mushroom

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