Investigating the impact of endometrial compaction on clinical pregnancy rate in artificial frozen-thawed embryo transfer cycles

Abstract

Objective: The aim of our study was to evaluate sonographic endometrial thickness succeeding the estrogen-only stage and on the day when embryo transfer (ET) occurred in artificial frozen embryo transfer (FET) cycles to delve into the effect of endometrial compaction (EC) on clinical pregnancy rate (CPR). Patients and Methods: In the first group endometrial thickness diminished when ET occurred when compared to the end of the estrogen-only phase (n:37). Endometrial thickness increased/did not alter for the second group (n:70). Demographic characteristics were recorded and the following were studied: in vitro fertilization (IVF) treatment indications, hormone levels, total antral follicle count, duration of infertility, embryo quality, embryo-fundus distance, endometrial thickness at the end of estrogen-only phase and on ET day, luteal support, CPR. Results: No significant difference occurred in CPRs (n:107). ET, on day 5 was higher in the first group (p<0.05). Regression analysis revealed EC was 8.000 times higher in those with ET day 5 than those with 3. Conclusion: Endometrial compaction is non-relevant to the rate of clinical pregnancy. The day of ET affected the presence of EC.

Keywords

• Endometrial compaction
• Artificial frozen embryo transfer cycles
• Clinical pregnancy rate
• Day of embryo transfer

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