Complete response with alternative combination chemotherapy in endodermal sinus tumor case of the ovary
Abstract
A 20 year old female with endodermal sinus tumor of the ovary, Stage III, underwent cytoreductive surgery and combination chemotherapy at Ankara Maternity Hospital, Ankara, Turkey. The patient was initially treated with Vincristine, Actinomycin and cyclophosphamide. The patient was followed by Alpha-feto- Protein which demonstrated a rise in titer which was then managed by Vinblastine, Bleomycin and CIS- platinum. The patient was documented to be in complete clinical and surgical remission by a "second- look" laparotomy. This is the first patient with an advanced germ cell tumor treated by aggresive surgery and multi-agent chemotherapy in Turkey.
Keywords
References
- Disaia PJ, Creasman WT. Clinical Gynecologic Oncology. Third Edition. CV Mosby Company. 1989; 423.
Details
Primary Language
English
Subjects
Clinical Sciences
Journal Section
Research Article
Publication Date
January 1, 1992
Submission Date
October 13, 2016
Acceptance Date
October 1, 1991
Published in Issue
Year 1992 Volume: 5 Number: 1