Acute asthmatic exacerbation and hospital admission may be
associated with severe influenza infection. It has been reported
that immunization with inactivated influenza vaccine in patients
with persistent asthma decreased respiratory illnesses and asthmarelated
events. Evidence from more recently published randomized
trials indicated that there is no significant increase in asthma
exacerbations immediately after influenza vaccination. Similarly,
inactivated influenza vaccine in chronic obstructive pulmonary disease
(COPD) patients resulted in a significant reduction in the total number
of exacerbations when compared with placebo. The highest incidence
of invasive pneumococcal disease occurs in children <5 years of age,
immunocompromised persons such as HIV, and those ≥65 years of
age. Therefore, pneumococcal vaccine has been recommended for
all adults ≥65 years of age and in younger patients who have a
condition that increases the risk of invasive pneumococcal disease
or pneumococcal pneumonia. The development of pneumococcal
conjugate vaccines represents a major advance, and the use of such
vaccine has reduced the incidence of pneumococcal disease and
acute exacerbation in COPD patients. There are limited data about
the effect of pneumococcal vaccine on asthmatic patients.
Subjects | Clinical Sciences |
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Journal Section | Review Makaleler |
Authors | |
Publication Date | November 27, 2016 |
Published in Issue | Year 2016 |