Diffusion-weighted MRI: In differential diagnosis of liver masses
Abstract
Objectives: The purpose of our study was to determine apparent
diffusion coefficients (ADCs) of focal liver lesions on the basis of
respiratory triggered diffusion-weighted single-shot echo-planar
MR imaging (DWI-SS-EPI) sequence and to evaluate whether
ADC measurements can be used to characterize lesions.
Patients and Methods: One hundred and eighteen patients with
134 focal liver lesions [35 cysts, 48 hemangiomas, 4 focal noduler
hyperplasias (FNH), 31 metastases, 14 hepatocellular carsinomas
(HCCs), 1 fibrolamellar carsinoma, 1 cholangiocellular carcinoma;
mean size 18.4 mm; range 10-140 mm] were examined on a 1.5-T
system using respiratory triggered DWI-SS-EPI (b-values: 50, 400,
800 s/mm2).
Results: Results were correlated with characteristic MRI
findings, histopathologic data and follow-up imagings. The
ADCs of different lesion types were compared and lesion
differentiation using optimal thresholds for ADCs was evaluated.
Mean ADCs (x10-3 mm2/s) were 2.15, 1.57, 1.16, 1.08, 1.03 for
cysts, hemangiomas, FNHs, metastases and HCCs, respectively.
Mean ADCs differed significantly for all lesion types except
metastases, HCCs and FNHs. Overall, 88.5% of lesions were
correctly classified as benign or malignant using a treshold value
of 1.20x10-3mm2/s.
Keywords
References
- Koyama T, Tamaki K,Togashi K. Current status of body MR imagings: Fast MR imaging and diffusion-weighted imaging. Int J Clin Oncol 2006; 11: 278-85. doi: 10.1007/s10147-006-0605-2
Details
Primary Language
English
Subjects
Clinical Sciences
Journal Section
Research Article
Authors
Rabia Ergelen
This is me
Türkiye
Cennet Sahın
This is me
Türkiye
Hacer Bal
This is me
Türkiye
Davut Tuney
This is me
Türkiye
Publication Date
October 15, 2016
Submission Date
December 26, 2016
Acceptance Date
July 17, 2016
Published in Issue
Year 2016 Volume: 29 Number: 3
Cited By
Hepatoselüler Karsinom ve Diğer Karaciğer Tümörlerinin Ayrımında Difüzyon Ağırlıklı Manyetik Rezonans Görüntülemenin Etkinliği
Dicle Tıp Dergisi
https://doi.org/10.5798/dicletip.661288