Research Article

Diffusion-weighted MRI: In differential diagnosis of liver masses

Volume: 29 Number: 3 October 15, 2016
  • Rabia Ergelen
  • Cennet Sahın
  • Hacer Bal
  • Davut Tuney
EN TR

Diffusion-weighted MRI: In differential diagnosis of liver masses

Abstract

Objectives: The purpose of our study was to determine apparent

diffusion coefficients (ADCs) of focal liver lesions on the basis of

respiratory triggered diffusion-weighted single-shot echo-planar

MR imaging (DWI-SS-EPI) sequence and to evaluate whether

ADC measurements can be used to characterize lesions.

Patients and Methods: One hundred and eighteen patients with

134 focal liver lesions [35 cysts, 48 hemangiomas, 4 focal noduler

hyperplasias (FNH), 31 metastases, 14 hepatocellular carsinomas

(HCCs), 1 fibrolamellar carsinoma, 1 cholangiocellular carcinoma;

mean size 18.4 mm; range 10-140 mm] were examined on a 1.5-T

system using respiratory triggered DWI-SS-EPI (b-values: 50, 400,

800 s/mm2).

Results: Results were correlated with characteristic MRI

findings, histopathologic data and follow-up imagings. The

ADCs of different lesion types were compared and lesion

differentiation using optimal thresholds for ADCs was evaluated.

Mean ADCs (x10-3 mm2/s) were 2.15, 1.57, 1.16, 1.08, 1.03 for

cysts, hemangiomas, FNHs, metastases and HCCs, respectively.

Mean ADCs differed significantly for all lesion types except

metastases, HCCs and FNHs. Overall, 88.5% of lesions were

correctly classified as benign or malignant using a treshold value

of 1.20x10-3mm2/s.

Keywords

References

  1. Koyama T, Tamaki K,Togashi K. Current status of body MR imagings: Fast MR imaging and diffusion-weighted imaging. Int J Clin Oncol 2006; 11: 278-85. doi: 10.1007/s10147-006-0605-2

Details

Primary Language

English

Subjects

Clinical Sciences

Journal Section

Research Article

Authors

Rabia Ergelen This is me
Türkiye

Cennet Sahın This is me
Türkiye

Hacer Bal This is me
Türkiye

Davut Tuney This is me
Türkiye

Publication Date

October 15, 2016

Submission Date

December 26, 2016

Acceptance Date

July 17, 2016

Published in Issue

Year 2016 Volume: 29 Number: 3

APA
Ergelen, R., Sahın, C., Bal, H., & Tuney, D. (2016). Diffusion-weighted MRI: In differential diagnosis of liver masses. Marmara Medical Journal, 29(3), 145-151. https://doi.org/10.5472/MMJoa.2903.02
AMA
1.Ergelen R, Sahın C, Bal H, Tuney D. Diffusion-weighted MRI: In differential diagnosis of liver masses. Marmara Med J. 2016;29(3):145-151. doi:10.5472/MMJoa.2903.02
Chicago
Ergelen, Rabia, Cennet Sahın, Hacer Bal, and Davut Tuney. 2016. “Diffusion-Weighted MRI: In Differential Diagnosis of Liver Masses”. Marmara Medical Journal 29 (3): 145-51. https://doi.org/10.5472/MMJoa.2903.02.
EndNote
Ergelen R, Sahın C, Bal H, Tuney D (October 1, 2016) Diffusion-weighted MRI: In differential diagnosis of liver masses. Marmara Medical Journal 29 3 145–151.
IEEE
[1]R. Ergelen, C. Sahın, H. Bal, and D. Tuney, “Diffusion-weighted MRI: In differential diagnosis of liver masses”, Marmara Med J, vol. 29, no. 3, pp. 145–151, Oct. 2016, doi: 10.5472/MMJoa.2903.02.
ISNAD
Ergelen, Rabia - Sahın, Cennet - Bal, Hacer - Tuney, Davut. “Diffusion-Weighted MRI: In Differential Diagnosis of Liver Masses”. Marmara Medical Journal 29/3 (October 1, 2016): 145-151. https://doi.org/10.5472/MMJoa.2903.02.
JAMA
1.Ergelen R, Sahın C, Bal H, Tuney D. Diffusion-weighted MRI: In differential diagnosis of liver masses. Marmara Med J. 2016;29:145–151.
MLA
Ergelen, Rabia, et al. “Diffusion-Weighted MRI: In Differential Diagnosis of Liver Masses”. Marmara Medical Journal, vol. 29, no. 3, Oct. 2016, pp. 145-51, doi:10.5472/MMJoa.2903.02.
Vancouver
1.Rabia Ergelen, Cennet Sahın, Hacer Bal, Davut Tuney. Diffusion-weighted MRI: In differential diagnosis of liver masses. Marmara Med J. 2016 Oct. 1;29(3):145-51. doi:10.5472/MMJoa.2903.02

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