Neonatal outcomes of preterm infants born to preeclamptic mothers

Abstract

Objectives: Preeclampsia is a major cause of maternal, fetal

and neonatal morbidity and mortality. The aim of this study was

to determine neonatal outcomes of premature infants born to

preeclamptic mothers.

Patients and Methods: Preterm infants ≤36 gestational age

who were born to preeclamptic mothers and normotensive mothers

were included in this study. Infant’s data including demographic

characteristics, neonatal morbidities and mortalities were evaluated

retrospectively.

Results: Hundred and forty infants born to preeclamptic

mothers (study group) and 144 infants born to normotensive

mothers (control group) were included. No statistical difference

was found between mean gestational age, birth weight, Apgar

scores at 1 and 5 minutes, and in terms of sex ratio. Cesarean

delivery, small gestational age and neutropenia rates were found

significantly higher in the study group. Other neonatal morbidities

such as necrotising enterocolitis and sepsis were also found

higher in the study group but it was not statistically significant.

Hospitalization and mortality rates were similar in both groups.

Conclusions: Preeclampsia was associated with increased

cesarean delivery, small gestational age and neutropenia. There

were no significant differences between other morbidities and

mortality of two groups. We think that prematurity is the main risk

factor of morbidity and mortality regardless of concomitant.

Keywords

• Preeclampsia,Premature infant,Neonatal mortality,Morbidity

References

1. Tavassoli F, Ghasemi M, Ghomian N, Ghorbani A, Tavassoli
2. S. Maternal and perinatal outcome in nulliparous women
3. complicated with pregnancy hypertension. J Pak Med Assoc
4. 2010; 60:707-10.