Laparoskopik kolesistektomi uygulanan olgularda safra kesesinin histopatolojik profili

Abstract

Amaç: Laparoskopik kolesistektomi uygulanan olgularda safra kesesi hastalıklarının dağılımını belirlemek amaçlanmıştır.

Hastalar ve Yöntem: Laparoskopik kolesistektomi uygulanan toplam 404 olguya ait kolesistektomi spesimeninin patolojik özellikleri tekrar gözden geçirildi. Olgulara ait lamlar ve patoloji raporları yeniden değerlendirildi.

Bulgular: Üçyüz iki olgu (%74,75) kadın, 102 olgu (%25,25) ise erkekti. Olguların yaş aralığı 16-80, yaş ortalaması 47,68±12,93 idi. En çok rastlanan hastalıklar 393 olguda görülen kolelitiazis ve 363 olguda görülen kronik kolesistitti. Ksantogranulomatöz kolesistitli tek olgumuzda safra kesesi intraoperatif olarak malignite açısından kuşkulu bulunmuştur. Kırk altı olguda metaplazi, dört olguda displazi ve sadece bir olguda insidental olarak adenokarsinom belirlendi.

Sonuç: Laparoskopik kolesistektomi uygulanan olgularda safra kesesinde malign tumor insidansı çok düşüktü (%0,24). Klinik olarak bulgu göstermeyen malignitelerin saptanabilmesi veya ksantogranulomatöz kolesistit gibi malignite kuşkusu oluşturan bulguların ekarte edilmesi için kolesistektomi spesimenlerinin rutin olarak, yeterli sayıda örneklerin histopatolojik incelemeye alınması gerektiği görüşündeyiz.

Keywords

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References

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