Bir ergende Takayasu arteritinin atipik presentasyonu

Year 2015, , 157 - 160, 28.11.2015

Kıymet Binnetoğlu Elif Karakoç Aydıner Safa Barış Ahmet Özen Ayşe Zöhre Feyyaz Baltacıoğlu Haner Direskeneli İşıl Barlan

https://doi.org/10.5472/MMJcr.2803.01

Cited By: 1

Abstract

Takayasu arteriti çocuklarda nadir görülen bir hastalıktır. Klinik
bulgular özgün değildir ve tanısal bir laboratuvar test mevcut
değildir. Burada, atipik bir klinikle başvuran bir ergende Takayasu
arteriti sunulmaktadır. Onbeş yaşında kız çocuk kliniğimize 2
aydır süren kilo kaybı, ateş, halsizlik ve sırt ağrısı ile başvurdu.
Fizik muayenede büyüme gelişmesi normal olan hastada
patolojik bulguya rastlanmadı. Laboratuvar testlerinde akut faz
reaktanları yüksek bulundu. Manyetik resonans ile anjiografik
görüntülemelerde aorta duvarında düzensizlik ve daralmalar
saptandı. Sonuç olarak, çocuklarda Takayasu arteritinde nonspesifik
bulgular görülmektedir. Laboratuvar testleri tanısal
olmamakla beraber radyolojik bulgular oldukça özgündür.
Tedavide sistemik steroidler ve immusupresanlar kullanılmakta
ancak çocuklarda seyir erişkinlerden daha ağır olmaktadır

Keywords

Ergen, HLAB51, Takayasu arteriti, Vaskülit

Atypical presentation of Takayasu’s arteritis in an adolescent

Abstract

Takayasu`s arteritis is rarely seen in childhood. In addition,
symptoms are nonspecific and diagnostic laboratory marker is
unavailable. We hereby described an adolescent with an atypical
presentation of Takayasu`s arteritis. A 15-year-old girl was admitted
to our clinic with the symptoms of weight loss, fever, back pain, and
malaise since 2 months. Physical examination ended with normal
vital signs, centiles and no other pathological findings. Laboratory
findings showed increased acute phase reactants. Irregularities
in the aortic wall and luminal narrowing of aorta were detected
in magnetic resonance angiography. In conclusion, children with
Takayasu`s arteritis present with nonspecific symptoms. No
laboratory test is diagnostic, whereas abnormalities in large vessels
in radiology are specific for the disease. Mainstay of treatment is
systemic steroids and immunosuppressants and outcome is worse
in children than in adults.

Keywords

Adolescent, HLAB51, Takayasu`s arteritis, Vasculitis

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