Research Article
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Year 2019, , 58 - 61, 31.05.2019
https://doi.org/10.5472/marumj.570904

Abstract

References

  • 1. Marshall K. Therapeutic applications of whey proteins. Altern Med Rev 2004; 9:136-56.
  • 2. Yalçın AS. Emerging therapeutic potential of whey proteins and peptides. Curr Pharm Des 2006; 12:1637 – 43. doi: 10.2174/138.161.206776843296
  • 3. Sies H. Oxidative stress: a concept in redox biology and medicine. Redox Biol 2015; 4:180-3. doi: 10.1016/j. redox.2015.01.002
  • 4. Meister A. Glutathione metabolism. Meth Enzymol 1995; 251:3-7. doi: 10.1016/0076-6879(95)51106-7
  • 5. Morcillo EJ, Estrela J, Cortijo J. Oxidative stress and pulmonary inflammation: pharmacological intervention with antioxidants. Pharmacol Res 1999; 40:393-404. doi: 10.3168/jds.S0022-0302(98)75613-9
  • 6. Grey V, Mohammed SR, Smountas AA, Bahlool R, Lands LC. Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein. J Cyst Fibrosis 2003; 2:195-8. doi: 10.1016/S1569-1993(03)00097-3
  • 7. Micke P, Beeh KM, Schlaak JF, Buhl R. Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients. Eur J Clin Invest 2001; 31:171-8. doi: 10.1046/j.1365-2362.2001.00781.x
  • 8. Ali A, Lee SJ, Rutherfurd-Markwick KJ. Sports and exercise supplements. In: Deeth HC, Bansal N, eds. Whey Protein from Milk to Medicine. London: Elsevier, 2019: 579, 635. doi: 10.1016/B978-0-12-812124-5.00017-5
  • 9. Assaf AM, Abbassi RA, Al-Binni M. Academic stressinduced changes in Th1 – and Th2-cytokine response. Saudi Pharm J 2017; 25:1237-47. doi: 10.1016/j.jsps.2017.09.009
  • 10. Goebel MU, Mills PJ, Irwin MR, Ziegler MG. Interleukin-6 and tumor necrosis factor-[alpha] production after acute psychological stress, exercise, and infused isoproterenol: differential effects and pathways. Psychosom Med 2000; 62:591-8.
  • 11. Apak R, Güçlü K, Özyürek M, Bektaşoğlu B, Bener M. Cupric ion reducing antioxidant capacity assay for antioxidants in human serum and for hydroxyl radical scavengers. Meth Mol Biol 2010; 594:215-39. doi: 10.1007/978-1-60761-411-1_15
  • 12. Laton M, Roper D. Investigation of the hereditary haemolytic anaemias: Membrane and enzyme abnormalities In: Bain BJ, Bates I, Laffan MA, eds. Dacie and Levis Practical Haematology. London: Elsevier, 2017: 228, 253. doi: 10.1016/B978-0-7020-6696-2.00012-6
  • 13. Kerasioti E, Kiskini A, Veskoukis A, et al. Effect of a special carbohydrate protein cake on oxidative stress markers after exhaustive cycling in humans. Food Chem Toxicol 2012; 50:2805-10. doi: 10.1016/j.fct.2012.04.015
  • 14. Kerasioti E, Stagos D, Priftis A, et al. Antioxidant effects of whey protein on muscle C2C12 cells. Food Chem 2014; 155:271-8. doi:10.1016/j.foodchem.2014.01.066
  • 15. Lands LC, Grey VL, Smountas AA. Effect of supplementation with a cysteine donor on muscular performance. J Appl Physiol 1999; 87:1381-5. doi:10.1152/jappl.1999.87.4.1381
  • 16. Sheikholeslami-Vatani D, Ahmadi-Kani Golzar F. Changes in antioxidant status and cardiovascular risk factors of overweight young men after six weeks supplementation of whey protein isolate and resistance training. Appetite 2012; 59:673-8. doi:10.1016/j.appet.2012.08.005
  • 17. Kang DH, Coe CL, McCarty DO. Academic examinations significantly impact immune responses, but not lung function, in healthy and well-managed asthmatic adolescents. Brain Behav Immun 1996; 10:164-81. doi: 10.1006/brbi.1996.0015
  • 18. Maes M, Song C, Lin A. et al. The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety. Cytokine 1998; 10:313-8. doi: 10.1006/cyto.1997.0290
  • 19. Glaser R, Kiecolt-Glaser JK. Stress-induced immune dysfunction: implications for health. Nat Rev Immunol 2005; 5:243-51. doi: 10.1038/nri1571
  • 20. Rojas IG, Padgett DA, Sheridan JF, Marucha PT. Stressinduced susceptibility to bacterial infection during cutaneous wound healing. Brain Behav Immunol 2002; 16:74-84. doi: 10.1006/brbi.2000.0619

Effect of casein and whey proteins on examination stress

Year 2019, , 58 - 61, 31.05.2019
https://doi.org/10.5472/marumj.570904

Abstract

Objective: In this study we aimed to evaluate the effects of
casein and whey protein supplementation on examination
stress. We have investigated different parameters of oxidative
stress and immune function.
Materials and Methods: The participants were divided
into three groups: control, casein and whey. Casein and whey
groups were supplemented with either casein or whey protein
for 15 days. Blood samples were obtained at the beginning of
the study (Day 0), on the examination day (Day 16) and five
days after the examination (Day 21). Antioxidant capacity,
glutathione, cortisol and cytokine levels (TNF-a, IL-6, IL-12)
were measured.
Results: An increase in antioxidant capacity and glutathione
levels of the participants using whey protein was observed.
Whey protein supplementation did not affect cortisol levels, but
participants taking whey protein showed an increase in serum
TNF-a and IL-6 levels.
Conclusion: It is suggested that the use of whey protein
strengthens the response to oxidative stress by increasing
antioxidant capacity and glutathione levels, while supporting
the immune system via cytokine release.

References

  • 1. Marshall K. Therapeutic applications of whey proteins. Altern Med Rev 2004; 9:136-56.
  • 2. Yalçın AS. Emerging therapeutic potential of whey proteins and peptides. Curr Pharm Des 2006; 12:1637 – 43. doi: 10.2174/138.161.206776843296
  • 3. Sies H. Oxidative stress: a concept in redox biology and medicine. Redox Biol 2015; 4:180-3. doi: 10.1016/j. redox.2015.01.002
  • 4. Meister A. Glutathione metabolism. Meth Enzymol 1995; 251:3-7. doi: 10.1016/0076-6879(95)51106-7
  • 5. Morcillo EJ, Estrela J, Cortijo J. Oxidative stress and pulmonary inflammation: pharmacological intervention with antioxidants. Pharmacol Res 1999; 40:393-404. doi: 10.3168/jds.S0022-0302(98)75613-9
  • 6. Grey V, Mohammed SR, Smountas AA, Bahlool R, Lands LC. Improved glutathione status in young adult patients with cystic fibrosis supplemented with whey protein. J Cyst Fibrosis 2003; 2:195-8. doi: 10.1016/S1569-1993(03)00097-3
  • 7. Micke P, Beeh KM, Schlaak JF, Buhl R. Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients. Eur J Clin Invest 2001; 31:171-8. doi: 10.1046/j.1365-2362.2001.00781.x
  • 8. Ali A, Lee SJ, Rutherfurd-Markwick KJ. Sports and exercise supplements. In: Deeth HC, Bansal N, eds. Whey Protein from Milk to Medicine. London: Elsevier, 2019: 579, 635. doi: 10.1016/B978-0-12-812124-5.00017-5
  • 9. Assaf AM, Abbassi RA, Al-Binni M. Academic stressinduced changes in Th1 – and Th2-cytokine response. Saudi Pharm J 2017; 25:1237-47. doi: 10.1016/j.jsps.2017.09.009
  • 10. Goebel MU, Mills PJ, Irwin MR, Ziegler MG. Interleukin-6 and tumor necrosis factor-[alpha] production after acute psychological stress, exercise, and infused isoproterenol: differential effects and pathways. Psychosom Med 2000; 62:591-8.
  • 11. Apak R, Güçlü K, Özyürek M, Bektaşoğlu B, Bener M. Cupric ion reducing antioxidant capacity assay for antioxidants in human serum and for hydroxyl radical scavengers. Meth Mol Biol 2010; 594:215-39. doi: 10.1007/978-1-60761-411-1_15
  • 12. Laton M, Roper D. Investigation of the hereditary haemolytic anaemias: Membrane and enzyme abnormalities In: Bain BJ, Bates I, Laffan MA, eds. Dacie and Levis Practical Haematology. London: Elsevier, 2017: 228, 253. doi: 10.1016/B978-0-7020-6696-2.00012-6
  • 13. Kerasioti E, Kiskini A, Veskoukis A, et al. Effect of a special carbohydrate protein cake on oxidative stress markers after exhaustive cycling in humans. Food Chem Toxicol 2012; 50:2805-10. doi: 10.1016/j.fct.2012.04.015
  • 14. Kerasioti E, Stagos D, Priftis A, et al. Antioxidant effects of whey protein on muscle C2C12 cells. Food Chem 2014; 155:271-8. doi:10.1016/j.foodchem.2014.01.066
  • 15. Lands LC, Grey VL, Smountas AA. Effect of supplementation with a cysteine donor on muscular performance. J Appl Physiol 1999; 87:1381-5. doi:10.1152/jappl.1999.87.4.1381
  • 16. Sheikholeslami-Vatani D, Ahmadi-Kani Golzar F. Changes in antioxidant status and cardiovascular risk factors of overweight young men after six weeks supplementation of whey protein isolate and resistance training. Appetite 2012; 59:673-8. doi:10.1016/j.appet.2012.08.005
  • 17. Kang DH, Coe CL, McCarty DO. Academic examinations significantly impact immune responses, but not lung function, in healthy and well-managed asthmatic adolescents. Brain Behav Immun 1996; 10:164-81. doi: 10.1006/brbi.1996.0015
  • 18. Maes M, Song C, Lin A. et al. The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety. Cytokine 1998; 10:313-8. doi: 10.1006/cyto.1997.0290
  • 19. Glaser R, Kiecolt-Glaser JK. Stress-induced immune dysfunction: implications for health. Nat Rev Immunol 2005; 5:243-51. doi: 10.1038/nri1571
  • 20. Rojas IG, Padgett DA, Sheridan JF, Marucha PT. Stressinduced susceptibility to bacterial infection during cutaneous wound healing. Brain Behav Immunol 2002; 16:74-84. doi: 10.1006/brbi.2000.0619
There are 20 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Original Research
Authors

Ramazan Celık This is me

Mahmut Sami Kaymakcı This is me

Deniz Akalın This is me

Enes Karademır This is me

Behlul Tuncer This is me

Gokhan Bıcım This is me

Ayse Mine Yılmaz This is me

A. Suha Yalcın

Publication Date May 31, 2019
Published in Issue Year 2019

Cite

APA Celık, R., Kaymakcı, M. S., Akalın, D., Karademır, E., et al. (2019). Effect of casein and whey proteins on examination stress. Marmara Medical Journal, 32(2), 58-61. https://doi.org/10.5472/marumj.570904
AMA Celık R, Kaymakcı MS, Akalın D, Karademır E, Tuncer B, Bıcım G, Yılmaz AM, Yalcın AS. Effect of casein and whey proteins on examination stress. Marmara Med J. May 2019;32(2):58-61. doi:10.5472/marumj.570904
Chicago Celık, Ramazan, Mahmut Sami Kaymakcı, Deniz Akalın, Enes Karademır, Behlul Tuncer, Gokhan Bıcım, Ayse Mine Yılmaz, and A. Suha Yalcın. “Effect of Casein and Whey Proteins on Examination Stress”. Marmara Medical Journal 32, no. 2 (May 2019): 58-61. https://doi.org/10.5472/marumj.570904.
EndNote Celık R, Kaymakcı MS, Akalın D, Karademır E, Tuncer B, Bıcım G, Yılmaz AM, Yalcın AS (May 1, 2019) Effect of casein and whey proteins on examination stress. Marmara Medical Journal 32 2 58–61.
IEEE R. Celık, M. S. Kaymakcı, D. Akalın, E. Karademır, B. Tuncer, G. Bıcım, A. M. Yılmaz, and A. S. Yalcın, “Effect of casein and whey proteins on examination stress”, Marmara Med J, vol. 32, no. 2, pp. 58–61, 2019, doi: 10.5472/marumj.570904.
ISNAD Celık, Ramazan et al. “Effect of Casein and Whey Proteins on Examination Stress”. Marmara Medical Journal 32/2 (May 2019), 58-61. https://doi.org/10.5472/marumj.570904.
JAMA Celık R, Kaymakcı MS, Akalın D, Karademır E, Tuncer B, Bıcım G, Yılmaz AM, Yalcın AS. Effect of casein and whey proteins on examination stress. Marmara Med J. 2019;32:58–61.
MLA Celık, Ramazan et al. “Effect of Casein and Whey Proteins on Examination Stress”. Marmara Medical Journal, vol. 32, no. 2, 2019, pp. 58-61, doi:10.5472/marumj.570904.
Vancouver Celık R, Kaymakcı MS, Akalın D, Karademır E, Tuncer B, Bıcım G, Yılmaz AM, Yalcın AS. Effect of casein and whey proteins on examination stress. Marmara Med J. 2019;32(2):58-61.