Diagnostic accuracy of noncompacted-to-compacted wall ratio criteria on CMRI for the diagnosis of left ventricular noncompaction

Year 2019, , 124 - 129, 31.10.2019

Deniz Alıs Ahmet Anil Sahın Arda Guler Ozan Asmakutlu

https://doi.org/10.5472/marumj.637581

Abstract

Objectives: To investigate the diagnostic accuracy of the current criterion, noncompacted-to-compacted (NC/C) wall ratio > 2.3 on

cardiac magnetic resonance imaging (CMRI) for the diagnosis of left ventricular noncompaction (LVNC).

Materials and Methods: We retrospectively enrolled 37 patients as an LVNC group and a total of 97 participants with ischemic,

hypertrophic, and dilated cardiomyopathy and healthy controls as a control group. The NC/C ratio was measured perpendicularly

on short-axis cine images for segments 1-16 and four-chamber cine images for the apex during the end-diastole. The sensitivity,

specificity, and diagnostic accuracy of NC/C ratio > 2.3 for the diagnosis of LVNC were calculated.

Results: LVNC patients comprised 24 males (64.8%) and 13 females (35.2%) with the mean age of 29.24 ± 11.79 years. The NC/C ratio

> 2.3 detected in all but one of the LVNC patients (97.3%). On the other hand, the specificity of NC/C ratio > 2.3 was 79.4% for the

diagnosis of the LVNC patients. Using NC/C ratio > 2.66 and > 2.8 yielded 91.9% sensitivity and 97% specificity, and 81% sensitivity

and 100% specificity, respectively.

Conclusion: NC/C ratio > 2.3 might lead to overdiagnosis of LVNC. We suggest using higher NC/C cut-off value in individuals

without high clinical suspicion of LVNC.

Keywords

Accuracy, Cardiomyopathy, CMR, Cut-off, Noncompaction

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