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Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant system ın parkınson’s dısease patıents

Year 1988, Volume: 1 Issue: 1 - Marmara Medical Journal, 6 - 8, 01.01.1988

A. Kilinç A.S. Yalgn Y. Taga K. Emerk D. Yalçin

Abstract

It has been suggested that among the factors that lead to neuron loss in substantia nigra in Parkinson's disease are stimulation of lipid peroxidation and deficiency of glutathione and glutathione peroxidase. In this study, the effect of neurodegenerative changes on plasma and erythrocytes were investigated in Parkinson's disease. The results were compared with age-matched controls. Increase in plasma lipid peroxide levels and erythrocyte susceptibility to lipid peroxidation were observed in patients with Parkinson's disease. Erythrocyte catalase activities were not changed whereas glutathione levels and glutathione peroxidase activities were decreased.

Our results suggest that erythrocyte membrane integrity is impaired in Parkinson's disease. We are carrying out more detailed studies to determine whether this is related to neurodegenerative changes observed in Parkinson’s disease and whether parkinsonians will benefit from antioxidant treatment.

Keywords

Antioxidant system Plasma Erythrocyte Lipid peroxidation Parkinson’s disease

Year 1988, Volume: 1 Issue: 1 - Marmara Medical Journal, 6 - 8, 01.01.1988

A. Kilinç A.S. Yalgn Y. Taga K. Emerk D. Yalçin

Abstract

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Details

Subjects Clinical Sciences
Journal Section Articles
Authors

A. Kilinç This is me

A.S. Yalgn This is me

Y. Taga This is me

K. Emerk This is me

D. Yalçin This is me

Publication Date January 1, 1988
Published in Issue Year 1988 Volume: 1 Issue: 1 - Marmara Medical Journal

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APA Kilinç, A., Yalgn, A., Taga, Y., Emerk, K., et al. (1988). Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant system ın parkınson’s dısease patıents. Marmara Medical Journal, 1(1), 6-8.
AMA Kilinç A, Yalgn A, Taga Y, Emerk K, Yalçin D. Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant system ın parkınson’s dısease patıents. Marmara Med J. January 1988;1(1):6-8.
Chicago Kilinç, A., A.S. Yalgn, Y. Taga, K. Emerk, and D. Yalçin. “Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant System ın parkınson’s dısease patıents”. Marmara Medical Journal 1, no. 1 (January 1988): 6-8.
EndNote Kilinç A, Yalgn A, Taga Y, Emerk K, Yalçin D (January 1, 1988) Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant system ın parkınson’s dısease patıents. Marmara Medical Journal 1 1 6–8.
IEEE A. Kilinç, A. Yalgn, Y. Taga, K. Emerk, and D. Yalçin, “Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant system ın parkınson’s dısease patıents”, Marmara Med J, vol. 1, no. 1, pp. 6–8, 1988.
ISNAD Kilinç, A. et al. “Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant System ın parkınson’s dısease patıents”. Marmara Medical Journal 1/1 (January 1988), 6-8.
JAMA Kilinç A, Yalgn A, Taga Y, Emerk K, Yalçin D. Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant system ın parkınson’s dısease patıents. Marmara Med J. 1988;1:6–8.
MLA Kilinç, A. et al. “Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant System ın parkınson’s dısease patıents”. Marmara Medical Journal, vol. 1, no. 1, 1988, pp. 6-8.
Vancouver Kilinç A, Yalgn A, Taga Y, Emerk K, Yalçin D. Erythrocyte susceptıbılıty to lıpıd peroxıdatıon and antıoxıdant system ın parkınson’s dısease patıents. Marmara Med J. 1988;1(1):6-8.