Two ribosomal kinase fractions have been partially purified from reticulocyte lysates by DEAE-cellulose and phosphocellulose column chromatography. These fractions autophosphorylated the majority of the bands and phosphorylated EF-1 and elF-2|3. Addition of GSSG (oxidized glutathione) produced a general decrease in phosphorylation. However, phosphorylation of elF-2|3 was enhanced in the presence of GSSG.
Subjects | Clinical Sciences |
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Journal Section | Review Makaleler |
Authors | |
Publication Date | December 1, 1993 |
Published in Issue | Year 1993 Volume: 6 Issue: 4 |