The effects of starvation and cold-restraint stress on
the rat stomach mucosa were investigated. Mucosal
damage was evaluated using light, transmission
(TEM) and scanning (SEM) electronmicroscopy. Light
microscopy revealed hemorrhagic areas as well as
cellular damage in the mucosa. At TEM level, severe
degenerative changes were especially observed at
parietal cells and chief cells of the fundic mucosa.
SEM demonstrated a totally necrotic appearance of
the mucosa at the ulcer region with widened gastric
pits devoid of lining epithelium. We conclude that
experimental stress conditions produce severe
gastric mocosal damage.
Subjects | Clinical Sciences |
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Journal Section | Review Makaleler |
Authors | |
Publication Date | November 1, 1994 |
Published in Issue | Year 1994 Volume: 7 Issue: 4 |